Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EEC-Directive 92/69 B.3
GLP compliance:
yes
Limit test:
yes

Test animals

Species:
other: rat / Wistar Crl:(WI)BR

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
other: 1% Aqueous carboxymethyl cellulose
Duration of exposure:
24 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
Signs of toxicity related to dose levels:
No treatment-related effects were found.
Gross pathology:
Effects on organs:
No treatment related findings in body weight or macroscopic
examination.
Other findings:
Signs of toxicity (local):
Red staining of the snout was observed on days 1 and/or 2
(2M). Brown or yellow staining by the test substance was
observed in the treated skin area in all animals during the
observation period.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU