Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Deichmann, W.B
Year:
1969
Bibliographic source:
Toxicology of Drugs and Chemicals, Academic Press, Inc., Volume 390

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: No guidline known
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Bromochloromethane
EC Number:
200-826-3
EC Name:
Bromochloromethane
Cas Number:
74-97-5
Molecular formula:
CH2BrCl
IUPAC Name:
bromo(chloro)methane
Constituent 2
Reference substance name:
2008263
IUPAC Name:
2008263

Test animals

Species:
rat
Strain:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Doses:
5 gr/kg

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
5 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Conclusions:
The LD50 of the test substance Bromochloromethane when administered by the oral route was greater than 5000 mg/kg bw.
Executive summary:

An acute oral study was performed and published in "Toxicology of Drugs and Chemicals" Deichmann, Academic Press and resulted in LD50 of the test substance Bromochloromethane of 5000 mg/kg bw.