Pregna-1,4-diene-3,20-dione, 9-bromo-6-fluoro-11-hydroxy-16-methyl-21-[(1-oxopentyl)oxy]-, (6.alpha.,11.beta.,16.alpha.)-

Flammability

Link to relevant study record(s)

Reference

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

14 Jan 2016 to 06 Jan 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Deviations:

no

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Remarks:

The substance in its delivery state was measured. The test substance melted when approached by the ignition flame. The flame extinguished within the start segment.

Validity criteria for the measurement of the flammability:

Target condition according to UN Manual N.1:	Actual condition according to the study:	Validity criteria met:
The report shall include the results of the tests (steps 1, 2, 3 and 4) and the chemical identity of gas evolved.	The results of the steps are stated. No gas evolution occured.	Yes
The rate of evolution of gas if step 4 is performed shall be stated.	No gas evolution occured.	Yes

 

Interpretation of results:

not classified based on GHS criteria

Conclusions:

Bromhydrin-valerat is classified as a not readily combustible solid when tested according to UNMTC Procedure N.1.

Executive summary:

The test was performed as stipulated in UN test procedure ‘Recommendations on the Transport of Dangerous Goods - Manual of Tests and Criteria’ (UN-MTC), Part III, sub-section 33.2.1.4.1, Test N.1 ‘Test method for readily combustible solids’. The substance was formed into a powder train about 250 mm long by 20 mm wide by 10 mm high on a non-combustible, non-porous and low heat-conducting base plate. 30 – 40 mm beyond the 100 mm timing zone, 1 mL of a wetting solution was added to the pile. A hot flame from a gas burner was applied to one end of the powder train until the powder ignites or for a maximum of 2 minutes. A preliminary screening test was performed to determine if propagation by burning with flame or smoldering occurs without wetted zone. The substance in its delivery state was measured. The test substance melted when approached by the ignition flame. The flame extinguished within the start segment. No further testing was required. Bromhydrin-valerat is classified as a not readily combustible solid when tested according to UNMTC Procedure N.1.

Description of key information

Flammability: Bromhydrin-valerat melted when approached by the ignition flame. The flame extinguished within the start segment. No further testing was required.

Self-heating properties: The study does not need to be conducted because Bromhydrin-valerat is completely molten at 160 °C.

Pyrophoric properties: The substance did not deliver indications of pyrophoric properties during the realization of other tests. The determination according to UN-MTC Procedure N.2 is not necessary.

Contact with water: Experience in production or handling shows that bromhydrin-valerat does not react with water.

Key value for chemical safety assessment

Flammability:

not classified

Justification for classification or non-classification

As a conclusion to the results listed above Bromhydrin-valerat does not have to be classified as flammable.