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EC number: 617-901-5
CAS number: 866607-35-4
The toxicity of T003066 to green algae Pseudokirchneriella subcapitata
was determined in a 72-h growth inhibition test according to the OECD
guideline 201 (GLP conditions). Due to the very low solubility of
JNJ-39453349-AAA (T003066) in test medium, concentration levels that
might be toxic for algae could not be reached. The 72h-NOEC for
inhibition of both growth rate and yield was at the concentration
obtained in 100% of a saturated solution prepared at a loading rate of
100 mg/L. This concentration was considered to be the maximum solubility
of the test item in test medium and was below the limit of detection.
The 72h-EC50 for both growth rate inhibition (ERC50) and yield
inhibition (EYC50) was beyond the range tested, i.e. exceeded the
maximum solubility of test item in test medium.
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