Registration Dossier

Physical & Chemical properties

Partition coefficient

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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
13 November - 2 December, 2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Principles of method if other than guideline:
The test was not feasible to complete
GLP compliance:
no
Remarks:
not mandatory
Type of method:
other: no method was suitable
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid

Study design

Analytical method:
not specified

Results and discussion

Partition coefficient
Key result
Type:
Pow
Remarks on result:
not determinable
Details on results:
Therefore it was not possible to determine de Pow.

Any other information on results incl. tables

The partition coefficient of the test item has been assessed with regard to A8 Partition Coefficient of EC 440/2008. The standard methods were considered not applicable for following reasons:

- the test item is a UVCB

- the solubility of test item in several reverse phase solvents (methanol, acetone, acetonitrile) was insoluble or only soluble in small amounts

- due to low solubility in water and n-octanol an estimation of partition coefficient based on these solubilities would be inaccurate

- there is no defined structure, therefore an estimation based on QSAR calculation is no possible

Applicant's summary and conclusion

Conclusions:
The log Pow was not determinable.
Executive summary:

The log Pow was not determinable due to intrinsic properties of the test item. The test item is a UVCB and the standard methods are not applicable to complex mixtures. The solubility of test item in several reverse phase solvents (methanol, acetone, acetonitrile) was insoluble or only soluble in small amounts. There is no defined structure, therefore an estimation based on QSAR calculation is no possible.