Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 243-378-4 | CAS number: 19856-23-6
Additional ecotoxological information
Administrative data
- Endpoint:
- additional ecotoxicological information
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Justification for type of information:
- Justification for Read Across is given in Section 13 of IUCLID.
Data source
Reference
- Reference Type:
- publication
- Title:
- Ecotoxicity studies of the levulinate ester series
- Author:
- Lomba L, Muñiz, S., Pino M., Navarro, E. and Giner, B.
- Year:
- 2 014
- Bibliographic source:
- Ecotoxicology (2014) 23:1484–1493
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: UNE-EN-ISO 11348-3 (2007) Water quality: determination of the inhibitory effect of water samples on the light emission of Vibrio fischeri (Luminescent bacteria test)
- Type of study / information:
- Determination of the inhibitory effect of water samples on the light emission of Vibrio fischeri (Luminescent bacteria test).
Test material
- Reference substance name:
- Similar substance 01
- Molecular formula:
- n.a
- IUPAC Name:
- Similar substance 01
Constituent 1
Results and discussion
Any other information on results incl. tables
EC50 = 5687±1325 mg/l.
Applicant's summary and conclusion
- Conclusions:
- EC50 (30 min) = 5687±1325 mg/l.
- Executive summary:
The inhibition of bioluminescence of Vibrio fischeri bacteria was assessed according to the UNE-EN-ISO 11348-3. The lyophilized V. fischeri were exposed to several dilutions for each of the chemical were prepared using a 2 % NaCl stock solution. The different concentrations ranges assessed for this bioassay were 0–20000 mg/l.
The solution equilibrated for 10 min at 15 °C, and subsequently, the first measurements were taken to obtain the initial luminescence; then 0.5 ml of each dilution to be tested was added to the cuvette. The inhibition of luminescence was measured after 30 min.
EC50 (30 min) = 5687±1325 mg/l.
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