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EC number: 947-313-7
CAS number: -
In an acute oral toxicity study performed
according to the OECD Guideline 423 and in compliance with GLP, a single
dose of 2000 mg/kg bw of the test substance solubilized in olive oil and
heated during 5 minutes at ca. 50°C was given by oral gavage to a group
of 6 female Sprague Dawley rats. Animals were then observed for
mortality, clinical signs and body weight changes for 14 days, and were
all sacrificed for macroscopic examinations.
No mortality occurred during the study. No
clinical signs related to the administration of the test item were
observed during the study The body weight evolution of the animals
remained normal throughout the study. The macroscopic examination of the
animals at the end of the study did not reveal treatment related
Rat Oral LD50 >2000 mg/kg bw.
Under the test conditions, the oral LD50 of
the test substance is >2000 mg/kg bw in rats. In accordance with OECD
Guideline 423, the LD50 cut-off of the test substance may be considered
to be higher than 5000 mg/kg bw by oral route in the rat. Therefore it
is not classified according to the Regulation (EC) No. 1272/2008 (CLP)
and according to the Globally Harmonised System of classification and
labelling of chemicals (GHS).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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