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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

No acute toxicity test data were available for exposure of tripropylene glycol n-butyl ether highers (TPnB-H) to aquatic invertebrates.  Therefore, 
a read across approach was used for short-term toxicity to aquatic invertebrates based on test results for tripropylene glycol n-butyl ether (TPnB)
and SYNALOX* 100-20B ( dipropyleneglycol n-butylether initiated alkoxylate, Mw = 750).

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
1 000 mg/L

Additional information

The 48 hr NOEC value for Daphnia magna exposed to TPnB was 1000 mg/L, while the 48 hr EL50 value in a study with SYNALOX*100 -20B was report as >100 mg/L, which was the highest concentration tested. The molecular weights for these two read across substances ranges from 248 (TPnB) to 750 for SYNALOX*100 -20B. The chemical structure and molecular weight of TPnB highers is closer to TPnB, therefore the TPnB toxicity endpoint was considered to be more accurate for read across.