Hyoscine

Acute Toxicity: inhalation

Administrative data

Endpoint:

acute toxicity: inhalation

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

other:

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Name:

Scopolamine (Hyoscine) - self classification

Implementation:

other: self classification

Related composition:

Hyoscine (Scopolamine)

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data lacking

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data lacking

Reason for no classification:

data lacking

Reason for no classification:

data lacking

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data lacking

Reason for no classification:

data lacking

Hazard category:

Acute Tox. 2

Hazard statement:

H300: Fatal if swallowed.

Hazard category:

Acute Tox. 1

Hazard statement:

H310: Fatal in contact with skin.

Hazard category:

Acute Tox. 2

Hazard statement:

H330: Fatal if inhaled.

Reason for no classification:

data lacking

Hazard category:

Eye Damage 1

Hazard statement:

H318: Causes serious eye damage.

Reason for no classification:

data lacking

Hazard category:

Skin Sens. 1A

Hazard statement:

H317: May cause an allergic skin reaction.

Reason for no classification:

data lacking

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data lacking

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data lacking

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

data conclusive but not sufficient for classification

Signal word:

Danger

Code:

GHS06: skull and crossbones

Code:

GHS05: corrosion

Code:

GHS07: exclamation mark

Hazard statement:

H300: Fatal if swallowed.

Hazard statement:

H310: Fatal in contact with skin.

Hazard statement:

H330: Fatal if inhaled.

Hazard statement:

H318: Causes serious eye damage.

Hazard statement:

H317: May cause an allergic skin reaction.

Precautionary statement:

P260: Do not breathe dust/fume/gas/mist/vapours/spray.

Precautionary statement:

P262: Do not get in eyes, on skin, or on clothing.

Precautionary statement:

P272: Contaminated work clothing should not be allowed out of the workplace.

Precautionary statement:

P280: Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

Precautionary statement:

P301+P310: IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

Precautionary statement:

P330: Rinse mouth.

Precautionary statement:

P302+P352: IF ON SKIN: Wash with plenty of water/…

Precautionary statement:

P310: Immediately call a POISON CENTER/doctor/…

Precautionary statement:

P361+P364: Take off immediately all contaminated clothing and wash it before reuse.

Precautionary statement:

P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Precautionary statement:

P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Precautionary statement:

P333+P313: If skin irritation or rash occurs: Get medical advice/attention.

Precautionary statement:

P403+P233: Store in a well-ventilated place. Keep container tightly closed.

Precautionary statement:

P501: Dispose of contents/container to ...

Materials and methods

Test material

Test material information

Constituent 1

Reference substance name:

Scopolamine

IUPAC Name:

Scopolamine

Constituent 2

Reference substance name:

Hyoscine

EC Number:

200-090-3

EC Name:

Hyoscine

Cas Number:

51-34-3

Molecular formula:

C17H21NO4

IUPAC Name:

(1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate