Registration Dossier
Registration Dossier
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EC number: 200-090-3 | CAS number: 51-34-3
Density
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015-08-27 to 2015-08-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Version / remarks:
- 2012
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- pycnometer method
- Type:
- density
- Density:
- 1.28 g/cm³
- Temp.:
- 19.99 °C
- Remarks on result:
- other: mean (two samples)
- Key result
- Type:
- relative density
- Density:
- 1.28 other: dimensionless
- Temp.:
- 20 °C
- Conclusions:
- The relative density was determined to be pSubstance (at 20°C)/pWater (compared to water at 4°C) = 1.2802 according to OECD Test Guidelines 109 (2012) and Regulation EC No. 440/2008 Part A. Method A.3.
Reference
The relative density of two independent samples has been determined with an absolute deviation of 0.0009.
Table 1: Calibration check of the pycnometer
Calibration sphere |
Volume nominal [cm^3] |
Volume determined [cm^3] |
Deviation from nominal Vol [%] |
Identification No.: 302, Diameter 41.275 |
36.81708 |
36.84320 |
0.07 |
Table 2: Weight of Scopolamine
Weight No. |
Vessel empty [g] |
Vessel + test item [g] |
Weight test item [g] |
1 |
16.417 |
28.731 |
12.314 |
2 |
16.418 |
28.656 |
12.238 |
Table 3: Density of Scopolamine
Weight No. |
Determined sample volume [cm^3] |
Weight test item [g] |
Temperature [°C] |
Density [g/cm^3] |
Relative Density [-] |
1 |
9.61564 |
12.314 |
19.99 |
1.2806 |
1.2806 |
2 |
9.56306 |
12.238 |
19.99 |
1.2797 |
1.2797 |
|
|
mean: |
19.99 |
1.2802 |
1.2802 |
|
|
absolute deviation |
0.0 |
0.0009 |
0.0009 |
|
|
Relative deviation [%] |
0.0 |
0.07 |
0.07 |
Description of key information
The relative density of p substance (20°C)/p water (4°C) = 1.2802 was determined ( According to OECD Test Guidelines 109 (2012) and Regulation EC No. 440/2008 Part A. Method A.3).
Key value for chemical safety assessment
- Relative density at 20C:
- 1.28
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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