Registration Dossier
Registration Dossier
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EC number: 201-368-7 | CAS number: 81-64-1
Endpoint summary
Administrative data
Description of key information
A GPMT (Guinea Pig Maximisation Test) is available. Twenty male albino guinea pigs were used to test the sensitizing potential of 1,4-dihydroxyanthraquinone.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Only two of the 20 guinea pigs tested reacted when given the challenge injection. The mean score for each of the two guinea pigs indicates a severe response.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
In a guinea pig maximization test on 20 animals only 2 animals showed a positive reaction.
Justification for classification or non-classification
In a guinea pig maximization test on 20 animals only 2 animals showed a positive reaction.
According to CLP classification criteria (Regulation (EC) No 1272/2008) a classification is therefore not justified.
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