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EC number: 630-473-4
CAS number: 14595-54-1
7.10.4/1: Repeated Insult Patch Study
= No reaction
? = Minimal
or doubtful response, slightly different from surrounding normal skin
All Enrolled Subjects (n=110)
panel of 110 male and female human volunteers participated in a repeat
insult patch test in which a 10 % solution of test material in Diethyl
Phthalate (DEP) was applied to the infrascapular area of the back of the
subjects under occlusive patches. 106 subjects completed the study.
During the induction phase nine patches were applied, separated by a 48
h interval. The patches were removed 24 h after application. Following a
10-13 days rest period, a challenge patch was applied and the sites
scored 48 and 72 hours after application.
no significant skin reactivity observed during the course of the study.
Test material did not induce significant skin irritation nor show any
evidence of induced allergic contact dermatitis in human subjects.
the conditions employed in this study, there was no evidence of
sensitisation to the test material at 10 %.
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