Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic / sediment

From authorative database HSDB The BCF of oil pink i.e 1-[(2-methoxyphenyl)azo]-2-naphthol in aquatic organisms was reported as 290000 using a measured log Kow of 7.5 and a recommended regression-derived equation. This BCF value indicates that bioconcentration in aquatic organisms will be an important fate process i.e chemical have concern for bioaccumulation in aquatic environment.

Additional information

Bioaccumulation: aquatic / sediment

Two results including predicted data from authorative database and validated models for bioaccumulation (BCF) endpoint of target chemical 1-[(2-methoxyphenyl)azo]-2-naphthol (Cas no. 1229-55-6) were summarized as follows:

 

First study from authorative database HSDB; 2017 suggest The BCF of oil pink i.e 1-[(2-methoxyphenyl)azo]-2-naphthol in aquatic organisms was reported as 290000 using a measured log Kow of 7.5 and a recommended regression-derived equation. This BCF value indicates that bioconcentration in aquatic organisms will be an important fate process i.e chemical have concern for bioaccumulation in aquatic environment.

Above result assist by prediction done using Bio-concentration Factor (v12.1.0.50374) module from ACD (Advanced Chemistry Development)/I-Lab to determine Bio-concentration Factor over the entire pH scale 1-14 of the test substance 1-[(2-methoxyphenyl)azo]-2-naphthol.BCF  estimated to be in the range 1066 to 3662 (dimentionless). This value indicates that the test substance 1-[(2-methoxyphenyl)azo]-2-naphthol was likely to be Bioaccumulative in aquatic organisms. 

Thus based on the above information for bioaccumulation endpoint, it can be concluded that the test substance 1-[(2-methoxyphenyl)azo]-2-naphthol (Cas no. 1229-55-6)is expected to be Bioaccumulative in aquatic environment as both studies indicate the chemical 1-[(2-methoxyphenyl)azo]-2-naphthol exceed the BCF threshold of 2000.