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EC number: 500-213-3 | CAS number: 68439-50-9 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 JAN - 14 FEB 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge : activated sludge from the aeration tank of a municipal biological waste water treatment plant (ARA Werdhölzi, Zürich), not adapted, not pre-conditioned
- Pretreatment: no
- Pretreatment: prior to the test the sludge was washed twice with tap water.
- Concentration of sludge: 30 mg/L dry matter in the final mixture - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- ThOD/L
- Initial conc.:
- 50.5 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Aerobic mineral salts medium
- Test temperature: 22 +/- 0.5 °C
- pH: 7.3 - 7.4
- Continuous darkness: yes, Thermostat cabinet in the dark
- Suspended solids concentration: 30 mg/L
TEST SYSTEM
- Culturing apparatus: 500 mL glass bottles (tightly closed with manometric BOD measuring devices) containing a total volume of test solution of 200 mL.
- Number of culture flasks/concentration: 2
- Measuring equipment: O2 update was measured by a manometric BOD measuring device,
SAMPLING
- Sampling frequency: daily
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2 replicates
- Reference control: 1 replicate
- Abiotic sterile control: no
- Toxicity control: no - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 50.0 mg/L (83.3 mgThOD/L)
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 95
- Sampling time:
- 28 d
- Results with reference substance:
- Sodium benzoate reached 95% biodegradation after 14 days.
- Validity criteria fulfilled:
- yes
- Remarks:
- Please refer to table 1 at "Any other information on results incl. tables"
- Interpretation of results:
- readily biodegradable
Reference
Validity criteria OECD 301F
Criterion from the guideline |
Outcome |
Validity criterion fulfilled |
Difference of extremes of replicate values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d window, as appropriate, is less than 20%. |
<14% |
yes |
Percentage degradation of the reference compound reached the pass level by day 14 (≥ 60%). |
95% after 14 days. |
yes |
The toxicity control should degrade to at least 35% (based on DOC) or at least 25% (based on ThOD or ThCO2) within 14 d. |
n.a. |
n.a. |
The oxygen uptake of the inoculum blank is normally 20-30 mg O2/L and should not be greater than 60 mg/L in 28 days. |
22 mg/L |
yes |
Description of key information
Readily biodegradable: 95% after 28 d (OECD 301F)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
The ready biodegradability of Alcohols, C12 -14 ethoxylated was assessed in six reliable studies. All studies were conducted according or equivalent to OECD-, ISO- or EU-guidelines.
A study conducted according to OECD 301 F was assessed as key study (Kolb, 2008). The O2 consumption of non-adapted activated sludge at a test material concentration of 50.5 mg/L was followed for 28 days. A degradation rate of 95% was reached after 28 days and the ten-day window criterion was met.
In a second study conducted according to OECD 301 F, performed with a test substance concentration of 100 mg/L, a degradation rate of 64% after 28 days was determined. The ten-day window criterion was not met (Kolb, 2004). Two supporting studies following ISO guideline 14593 determined degradation rates of 125% and >60% based on CO2 evolution (Huntsman, 2006a/b). The tests were conducted with non-adapted activated sludge as inoculum and test substance concentrations of 13.5 mg/L and 27 mg/L respectively. In two supporting studies set up according to EU method C.4-D degradation rates of 78.6% and 71.2% based on O2 consumption were recorded (Rokita, 2005 and 2007). The test substance concentration in both tests was 100 mg/L.
In addition a short abstract on a study conducted according to EU method C.4-D a biodegradation rate of 79% after 28 days is reported based on O2 –consumption (BASF, 1998).
Based on the results of the available studies Alcohols, C12 -14 ethoxylated is assessed as readily biodegradable according to OECD criteria.
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