Registration Dossier
Registration Dossier
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EC number: 206-991-8 | CAS number: 409-21-2
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vitro / ex vivo
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Executive summary:
Silicon carbide (crude and grains) is an inert chemical and is likely to cause mechanical eye irritation due to large particle size and shape. Mechanical eye irritation produced by silicon carbide would camouflage any chemical irritation that might be caused by the substance. For this reason and due to the unethical aspect of in vivo eye irritation testing of a mechanical irritant, it was not considered reasonable to perform an eye irritation study.
In addition, documented occupational experience with the handling and use of silicon carbide (crude and grains) has revealed no cases of eye or dermal corrosion (i.e. irreversible damage to the skin or to the eye).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
