Registration Dossier
Registration Dossier
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EC number: 203-632-7 | CAS number: 108-95-2
Endpoint summary
Administrative data
Description of key information
Additional information
Bioaccumulation
Ten reports on bioaccumulation of phenol in 6 fish species are available. Nine studies are based on measured values, however, only 5 studies are regarded reliable. One study calculated the BCF using an equation derived from studies with 30 chemicals and Pimephales promelas (Veith et al. 1979). This equation is also given in the Technical Guidance Document. Only the study of Butte et al. (1985) was conducted according to OECD guideline 305E under flow-through conditions using Danio rerio. The BCF was calculated from kinetic parameters (accumulation-/clearance phase). The BCF for total fish was calculated to be 17.5. The depuration half-life (DT50) was calculated to be 0.83 hours and the DT90 was 2.75 hours.
As a conclusion from the available test results it can be stated that phenol has only a low bioaccumulation potential. This is also supported by the log Kow of 1.47. According to the equation of Veith et al. (1979) given in the TGD a BCFfish of 3.5 can be calculated from this value. For the further assessment the BCF of 17.5 found by Butte et al. (1985) is used.
Two reliable studies on bioaccumulation of phenol in green algae are also available with BCF values between 1.08 and 6.55 (max. BCF based on dry weight) confirming the low bioaccumulation potential of phenol.
Regarding bioaccumulation in terrestrial environment, no reliable studies are available. Due to the low log Pow and the insignificant bioaacumulation potential in aquatic species, an experimental study does not seem justified
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