Registration Dossier
Registration Dossier
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EC number: 939-227-3 | CAS number: -
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
The two sesquiterpene hydrocarbon constituents, Alpha-guaiene and Alpha-bulnesene, were found to have LC50 of 766mg/kg and 420mg/kg respectively following 14-day exposure to earthworms.
Key value for chemical safety assessment
Additional information
Alpha-guaiene is a constituent of the registration substance, patchouli oil, and represents the hydrocarbon fraction (with lower boiling point) that has the potential to adsorb to organic matter. The acute earthworm LC50 is 766mg/kg after 14 days exposure to alpha-guaiene fraction of patchouli oil. The LOEC is 1000mg/kg and the NOEC is 560mg/kg.
Alpha-bulnesene is a constituent of the registration substance, Patchouli ext., and represents the hydrocarbon fraction (with higher boiling boint) that has the potential to adsorb to organic matter. The acute toxicity of the Alpha-bulnesene, to earthworm Eisenia fetida, in an artificial soil test has been investigated and gave a 14 Day LC50 value of 420 mg/kg with 95% confidence limits of 320-560 mg/kg. The Lowest Observed Effect Concentration was considered to be 560 mg/kg. The No Observed Effect Concentration was 180 mg/kg.
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