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EC number: 905-588-0
CAS number: -
The lowest result is a 24 hour EC50 of 1 mg/L for o-xylene.
Data are available on the acute toxicity of
each of the xylene isomers and ethylbenzene to aquatic invertebrates.
The study by Galassi et al (1988) follows OECD 202 and uses Daphnia
magna, whilst Holcombe et al (1987) used a flow through system to
expose different species (including Daphnia magna)
simultaneously. Niederlehner et al (1998) used Ceriodaphnia dubia as
the test organism. All studies included analytical confirmation of the
The lowest result listed in the EU RAR (ECB
2007) and the Draft Screening Assessment Report (Environment Canada
2014) for acute toxicity of ethylbenzene to invertebrates is a 48 hour
EC50 of 1.8 mg/L (Vigano 1993). The ECB report that the study
investigated the toxicity of ethylbenzene to Daphnia magna in
completely filled, closed bottles, with results based on mean measured
concentrations. The results were taken from a larger study on the
effects of different food rations on juvenile Daphnia. Although
lower results are reported by Benville and Korn (1977) are reported in
the EU RAR, the test result is not considered valid as it is not known
how the mean exposure concentration over the whole test duration was
calculated and no attempt was made to supplement the toxicant.
The 24 and 48 hour EC50 results reported from
these studies for the xylene isomers and ethylbenzene are very similar,
with a range of 1 - 4.7 mg/L. In the study by Niederlehner et al (1998),
the highest concentration tested did not result in effects on mortality,
so the EC50 is > 3.4 mg/L. The lowest result will be used in the risk
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