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EC number: 905-588-0
CAS number: -
Acute aquatic ecotoxicity data are not
available for any of the streams in this category. However, complete
acute datasets are available for each of the xylene isomers and
ethylbenzene. Data from a chronic fish study are available for mixed
xylenes. Data from chronic invertebrate and algal studies are available
for m and p xylene and ethylbenzene. We believe that it is appropriate
to read across the data from the components to the streams in this
Ethylbenzene and the xylene isomers are
structurally similar substances, consisting of a benzene ring with one
and two methyl functional groups attached respectively; the different
xylene isomers having the two methyl functional groups attached at
different locations. The presence and position of the second methyl
functional group on the benzene ring is not expected to change the
ecotoxicity properties of the substance significantly. The similarities
in the physico-chemical properties of the components of the stream
indicate that the ecotoxicity of the components is likely to be similar.
All of the components are relatively soluble in water, with limited
potential partition coefficients. The water solubility (Yalkowsky and He
2003) and log partition coefficient (Hansch et al. 1995) of
ethylbenzene, m-, o- and p-xylene are 190.7 mg/L and 3.15, 146 mg/L and
3.2, 170.5 mg/L and 3.12, and 156 mg/L and 3.15 respectively.
The data on the xylene isomers has been taken
from proprietary studies or published journal articles, for which the
original sources have been reviewed. A literature search was undertaken
and data were evaluated for relevance and reliability using the Klimisch
scoring system. Sufficient reliable data were identified for completion
of the ecotoxicity sections of the REACH registration dossiers for the
individual xylene isomers and the data has been used for the hazard
assessment of the streams.
A data search on ethylbenzene identified
published studies and regulatory review documents. As ethylbenzene is
used as a marker substance for the streams in this category, it was
considered suitable to use the review documents as reliable secondary
sources for inclusion as additional evidence, without evaluating the
The European Risk Assessment Report (ECB
2007) was prepared by the German Competent Authority and interested
companies following the methods set out in Commission Regulation (EC)
1488/94 and the associated Technical Guidance Document. The document has
been peer-reviewed by the Scientific Committee on Health and
Environmental Risks (SCHER) and therefore the report is considered to be
a reliable source of information. Only studies which addressed the
volatility of ethylbenzene (using flow through or closed systems with
analytical measurement) were considered for inclusion in the review of
the aquatic ecotoxicity data.
The Draft Screening Assessment Report
(Environment Canada 2014) was prepared by the Existing Substances
programs at Health Canada and Environment Canada and has undergone
external written scientific peer review/consultation. Data were taken
from recent literature searches (up to December 2009 for ecological
sections) and review and assessment documents. When available and
relevant, information presented in hazard assessments from other
jurisdictions was considered. The key studies were critically evaluated,
with the screening assessment presenting the most critical studies and
lines of evidence pertinent to the conclusion.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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