4-methylmorpholine

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising liquids

Type of information:

other: Expert statement

Adequacy of study:

key study

Study period:

2011

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Statement prepared under GLP conditions.

Qualifier:

according to guideline

Guideline:

EU Method A.21 (Oxidising Properties (Liquids))

Version / remarks:

(Expert statement)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

- Name of test material (as cited in study report): Jeffcat NMM
- Physical state: Liquid
- Analytical purity: 99.54%
- Purity test date: 01-06-2007
- Lot/batch No.: LL077604

Key result

Sample tested:

other: Based on expert statement

Parameter:

other: chemical structure; groups associated with oxidising properties, eletronegative atoms bound to high proportions bound to high oxidation state and electonegative atoms bonded to electronegative elements

Remarks on result:

other: The structural formula does not contain any of the parameters mentioned above. The substance is not expected to exhibit oxidising properties

Examining the structural formula, the following observations can be made:

- The molecule does not contain any functional groups such as organic nitro compounds, N-Halogen Compounds (N-X), Oxohalogen compounds, Interhalogen compounds

- According to the two criteria quoted, oxidising properties can exist when:

- the electronegative atoms which are present constitute a high proportion of the molecule and are bound to elements in a high oxidation state -> In the case of Jeffcat NMM the proportion of electronegative atoms of the molecule is low (1 oxygen atom out of an overall atom count of 18). The oxygen atom is bound to carbon atoms.

- the electronegative atoms are bonded to each other or to other electronegative elements such as iodine, nitrogen, sulphur or phosphorus -> in the case of Jeffcat NMM, the electronegative atoms are not bound to one another, nor to any other electronegative elements.

- Assessment against these two criteria indicates strongly that the molecule will not have oxidising properties

In every respect of the oxidising liquids exemption procedure, Jeffcat NMM does not show any evidence of possessing oxidising properties.

On the basis of this exercise, the material should be considered as not oxidising and should not be subjected to experimental testing.

Interpretation of results:

GHS criteria not met

Conclusions:

The substance is concluded not to have oxidising properties. The substance meets all criteria for exemption from testing and has a structure not at all conducive with that required to exhibit oxidising tendencies.

Description of key information

The test substance was concluded not to have oxidising properties following a theoretical assessment of the chemical structure, under GLP (Younis, 2011).

Key value for chemical safety assessment

Oxidising properties:

non oxidising

Justification for classification or non-classification

The test substance does not need to be classified as an oxidising substance as based on the chemical structure the substance does not contain any chemical groups indicating oxidising properties.