Registration Dossier

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test was conducted according to OECD 209 and compliant with GLP.

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1990

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
not specified
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test organisms

Test organisms (species):
activated sludge

Study design

Test type:
other: aerobic
Total exposure duration:
0.5 h

Results and discussion

Effect concentrations
Duration:
30 min
Dose descriptor:
IC50
Effect conc.:
> 5.9 mg/L
Conc. based on:
test mat.

Any other information on results incl. tables

NOEC (mg/L): 30 minutes: supersaturated solution of the substance was generated using 50 mg in 500 ml. This is well in excess of solubility and would have resulted in a maximum dissolved concentration of 5.9 mg/L (but is likely to have been considerably lower by comparison with the concentrations achieved in the other tests carried out on the substance). No effects were seen on respiration of the sludge at the maximum attainable concentration.

Applicant's summary and conclusion