Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test was conducted according to Directive 84/449/EEC, C.1 and compliant with GLP.

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1991

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Directive 84/449/EEC, C.1
Deviations:
not specified
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: 25 ml standard solution containing 3 g test substance and 80 mg alkylphenol-polyglycol ether in N-methylpyrrolidone.

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
semi-static
Total exposure duration:
96 h

Test conditions

Hardness:
175 mg CaCO3/L

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
0.47 mg/L
Basis for effect:
mortality
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
0.46 mg/L
Basis for effect:
mortality
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
0.46 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
0.46 mg/L
Basis for effect:
mortality
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
0.3 mg/L
Details on results:
% Concentration loss over test: 82 to 95

Applicant's summary and conclusion

Conclusions:
The substance is very toxic to aquatic life (both short term and long term).