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Toxicological information

Carcinogenicity

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Description of key information

Although Column 2 of REACH Annex X requires a carcinogenicity study (required in Section 8.9.1) if the substance has a wide dispersive use, the weight of evidence across the category suggests that Undecanol linear and branched is not carcinogenic. This is based on a large set of various types of repeated dose studies across the category which do not offer any evidence of treatment-related induction of hyperplasia / pre-neoplastic lesions for Reaction mass of 2-butylheptan-1-ol and 2-ethylnonan-1-ol and 2-methyldecan-1-ol and 2-propyloctan-1-ol, or structurally related alcohols (though reporting is limited in many cases). In addition, Reaction mass of 2-butylheptan-1-ol and 2-ethylnonan-1-ol and 2-methyldecan-1-ol and 2-propyloctan-1-ol does not have any genotoxic effects.

Key value for chemical safety assessment

Additional information

Justification for classification or non-classification

Based on the weight of evidence, the data is waived as testing is not a scientifically necessary option for this endpoint.