Registration Dossier
Registration Dossier
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EC number: 443-940-0 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The adsorption coefficient (log Koc) of the test substance was determined to be <1 using HPLC method.
Key value for chemical safety assessment
- Koc at 20 °C:
- 1
Additional information
A study was performed to determine the adsorption coefficient (log Koc) of the test substance according to EU Method C.19. and OECD Guideline 121.
Test was conducted using HPLC method. The dead time was determined by using a "dead time marker". For calibration the retention times of a series of substances with known adsorption coefficients were measured and a calibration graph was established. The adsorption coefficient of the test substance was derived from its retention time and the calibration graph.
The retention time of the test substance had approximately the retention time of the dead time marker. The difference of the retention time between two measurements is low. Due to this fact it is only possible to give a log Koc value for the test substance that is lower than the first calibration standard.
The first calibration standard is benzamide and the log Koc value is 1.
The dead time was determined to be 3.52 min and log Koc of the test substance at four measurements was <1.
The adsorption coefficient (log Koc) of the test substance was determined to be >1 (Schminke A, 2002).
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