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EC number: 248-096-5 | CAS number: 26896-48-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
TCD Alcohol DM was determined to be not readily biodegradable.
In a surface water simulation test (OECD TG 309) with river water (SPM 13 mg DW/L), TCD Alcohol DM was first rapidly oxidized to an isomeric mixture of TCD Monoacids (apparent first order DT50 0.121 d - 0.235 d at 20 µg/L initial concentration), followed by a rapid further oxidation to the TCD Diacids under steady decrease of the TCD Monoacids. The concentration of the TCD Diacids remained in a plateau to the end of the study.
Additional information
In the reliable key study, octahydro-4,7-methano-1H-indenedimethanol (TDC-Alcohol DM) was assessed for ready biodegradability in the CO2 -evolution test according to OECD 301B (LAUS, 2015). No degradation was observed within 28 days (0% within both replicates). Therefore, the test item must be considered to be not readily biodegradable, and no indication for inherent biodegradability is given by these results. No inoculum toxicity was observed at a concentration of 29.0 mg/L.
This is supported by a MITI (I)-Test with TCD-Alcohol DM, following OECD TG 301 C. No relevant degradation (1 %) was observed and the compound assessed to be not biodegradable (NITE, 2004).
The simulation degradation testing (OECD TG 309; Noack, 2021) with river water (SPM 13 mg DW/L) performed at 12 °C over 65 days on cold test item TCD Alcohol DM had the following results: Transformation of TCD Alcohol DM started directly after application. Already after two days, the detected concentration was < 10 % of the applied concentration.
The TCD Alcohol DM isomers 1, 2 and 3 were first oxidized to an isomeric mixture of TCD Monoacids followed by further oxidation to the TCD Diacids under steady decrease of the TCD Monoacids. The concentration of the TCD Diacids remained in a plateau to the end of the study.
Apparent first order DT50 for TCD Alcohol DM: 0.121 d - 0.235 d (20 µg/L initial conc.); 0.585 d - 0.669 d (100 µg/L initial conc.).
A study on sediment simulation testing is scientifically not necessary: TCD Alcohol DM does not have a high potential for adsorption (log Kow < 3 IUCLID Sect. 4.7, low estimated Koc of 16.8, IUCLID Sect. 5.4.1). Based on the valid simulation test on degradation in surface water (OECD TG 309; Noack, 2021), TCD Alcohol DM is rapidly transformed to the dicarboxylic acid derivative. Any losses due to adsorption could reliably be excluded based on a mass balance of ca. 100 %. No relevant further information could be expected from additional simulation testing with sediment.
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