Registration Dossier
Registration Dossier
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EC number: 203-537-0 | CAS number: 107-96-0
Developmental toxicity / teratogenicity
Administrative data
- Endpoint:
- developmental toxicity
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Irrelevant route of exposure
Data source
Reference
- Reference Type:
- publication
- Title:
- Cleft palate by picrotoxin or 3-MPA and palatal shelf elevation in GABA-deficient mice.
- Author:
- Ding, R. Tscunekawa, N. and K. Obata.
- Year:
- 2 004
- Bibliographic source:
- Neuroltoxicol. Teratol. 26(4):587-592. July-August.
Materials and methods
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-mercaptopropionic acid
- EC Number:
- 203-537-0
- EC Name:
- 3-mercaptopropionic acid
- Cas Number:
- 107-96-0
- Molecular formula:
- C3H6O2S
- IUPAC Name:
- 3-sulfanylpropanoic acid
- Details on test material:
- IUCLID4 Test substance: as prescribed by 1.1 - 1.4
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
Administration / exposure
- Route of administration:
- other: subcutaneous injection or continuous infusion
- Details on study design:
- Sex: female
Results and discussion
Results (fetuses)
Fetal abnormalities
- Abnormalities:
- not specified
Overall developmental toxicity
- Developmental effects observed:
- not specified
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
