Registration Dossier
Registration Dossier
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EC number: 203-537-0 | CAS number: 107-96-0
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 17 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 170 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 1.7 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 3.933 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.347 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.035 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.06 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The influence of the test item 3-mercaptopropionic acid on aquatic organisms representing three different trophic levels was investigated in three acute studies in accordance with OECD guidelines and GLP principles. The acute toxicity determined was as follows: Brachydanio rerio 96 h-LC50 = 270 mg/L, Daphnia magna 48 h-EC50 = 17 mg/L, and Selenastrum capricornutum 72 h-ErC50 = 32.6 mg/L. In conclusion, the aquatic invertebrate Daphnia magna was the most sensitive organism tested with a 48 h-EC50 of 17 mg/L.
Furthermore, inhibitory effects on the respiration of activated sludge were also tested in an OECD guideline study under GLP. The study resulted in a 3 h-EC50 of 393.3 mg/L. The 3 h-EC10 was determined to be 32.1 mg/L.
Conclusion on classification
Potential threats of 3-mercaptopropionic acid to the aquatic environment were determined in different ecotoxicological studies using different test species. All studies are conclusive and the results do not lead to a classification.
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