Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 209-984-8 | CAS number: 600-14-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
- Category name:
- Penta-2,3-dione acute toxicity category
Justifications and discussions
- Category definition:
- Scenario 6, “Different compounds have the same type of effect(s)”
- Category rationale:
- 1. CATEGORY HYPOTHESIS
This read-across hypothesis is based on a category approach. Within the category, it is hypothesised that, based on structural similarity, the physico-chemical and toxicological properties are likely to be similar or follow a regular pattern in category members. Of the category approaches detailed in the RAAF guidance document, Scenario 6, “Different compounds have the same type of effect(s)” is considered the most appropriate hypothesis for this read-across. Scenario 6 is further defined such that “No relevant variations in properties observed among source substances and the same strength predicted for the target substance”. AEs specific to Scenario 6 in the RAAF document are considered in the read-across document.
2. CATEGORY JUSTIFICATION
The structural similarities between the target and the source substances presented in the document supporting the category approach. Adequate, reliable data indicate that the target and source substances have similar physico-chemical and toxicity profiles that support the application of the category approach as an appropriate read-across method. The target substance is of comparable molecular weight to the majority of the source substances, and the only source substance that is larger than the target substance would be expected to dissociate into isomers of the target substance. These isomers would be of equal molecular weight. Consequently, it is considered that any toxicity observed with any of the source substances presented in this category will be similar to the toxicity of the target.
3. APPLICABILITY DOMAIN OF THE CATEGORY
The structural similarities between the target and the source substances presented in the document supporting the category approach. The target substance is of comparable molecular weight to the majority of the source substances.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.