Registration Dossier
Registration Dossier
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EC number: 619-946-6 | CAS number: 890707-29-6
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- June 2009 - September 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7370 (Dissociation constants in water)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-Amino-5-cyano-N,3-dimethylbenzamide
- Cas Number:
- 890707-29-6
- Molecular formula:
- C10H11N3O
- IUPAC Name:
- 2-Amino-5-cyano-N,3-dimethylbenzamide
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
- Dissociating properties:
- no
Applicant's summary and conclusion
- Conclusions:
- The test substance was non dissociative under the test condition.
- Executive summary:
The present study was conducted to determine the dissociation constant of the test substance using a potentiometric titration method following OECD Guideline 112 and OPPTS 830.7370.
The dissociation constant was determined using a potentiometer to measure the change in potential after incremental additions of an alkali solution and an acid solution to an aqueous solution of the test substance at 20 ± 0.5°C.The data showed no dissociation under the test condition.
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