Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.014 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.001 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
4.7 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
26.1 mg/kg sediment dw
Assessment factor:
1
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.521 mg/kg soil dw
Assessment factor:
1
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential to cause toxic effects if accumulated (in higher organisms) via the food chain

Additional information

Conclusion on classification

In accordance with Regulation (EC) No. 1272/2008 (CLP), a substance should be classified as an acute aquatic hazard if the 96-hr LC50 for fish, the 72- or 96-hr EC50 for algae, or the 48-hr EC50 for crustaceans is 1 mg/L or less. The reliable short-term toxicity (LC50/EC50) of tetraammineplatinum(II) hydrogen carbonate to aquatic invertebrates (Daphnia magna) is 28 mg/L (Lebertz, 1997) while the short-term toxicity of the related substance tetraammineplatinum(II) diacetate to aquatic species for the remaining trophic levels ranges from 52 mg/L to > 100 mg/L (Migchielsen, 2006a; 2006b). Therefore tetraammineplatinum(II) hydrogen carbonate does not require classification as an acute aquatic hazard under CLP.

 

Under CLP, a substance may be classified as a chronic aquatic hazard if adequate chronic toxicity data (chronic NOEC or EC value) are available for at least one trophic level (and with a consideration of biodegradability). Biodegradation is not considered to be a relevant endpoint for tetraammineplatinum(II) hydrogen carbonate. Nevertheless, based on the ‘chronic’ NOEC of 1.0 mg/L (0.47 mg Pt/L) identified in the 72-hr algal growth inhibition study on the related substance tetraammineplatinum(II) diacetate (Migchielsen, 2006b) and considering that tetraammineplatinum(II) hydrogen carbonate has a harmonised classification for aquatic chronic toxicity (category 3) according to Annex VI of the CLP regulation, as such this classification is adopted here.