Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 223-358-1 | CAS number: 3852-09-3
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Study period:
- 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Proposed criterion (USEPA 2004) for an overall YES or NO Ready Biodegradability prediction are as
follows: If Biowin3 (ultimate survey model) result is “weeks” or faster (e.g. days or days
to weeks) ≥2.75 AND Biowin5 (MITI linear model) ≥0.5, then the prediction is YES
(readily biodegradable). If this condition is not satisfied, the prediction is NO (not readily
biodegradable). - Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6 May 2008
- Principles of method if other than guideline:
- BIOWIN 3
- Parameter:
- other: BIOWIN 3
- Value:
- 3.07
- Remarks on result:
- other: result corresponds to "Weeks"
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Study period:
- 2016
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- Proposed criterion (USEPA 2004) for an overall YES or NO Ready Biodegradability prediction are as
follows: If Biowin3 (ultimate survey model) result is “weeks” or faster (e.g. days or days
to weeks) ≥2.75 AND Biowin5 (MITI linear model) ≥0.5, then the prediction is YES
(readily biodegradable). If this condition is not satisfied, the prediction is NO (not readily
biodegradable). - Guideline:
- other: REACH Guidance on QSARs R.6, May 2008
- Parameter:
- other: BIOWIN 5
- Value:
- 0.806
- Remarks on result:
- other: Result corresponds to "Biodegrades Fast"
Referenceopen allclose all
Description of key information
The biodegradability of methyl 3 -methoxypropionate is estimated by Biowin.
Criteria for the YES or NO Ready Biodegradability prediction: If the Biowin3 (ultimate survey model) result is "weeks" or faster (i.e. "days", "days to weeks", or "weeks" AND the Biowin5 (MITI linear model) probability is >= 0.5, then the prediction is YES (readily biodegradable). If this condition is not satisfied, the prediction is NO (not readily biodegradable).
Methyl 3 -methoxypropionate results for Biowin3 in weeks and results for Biowin5 in 0.8. Therefore, methyl 3 -methoxypropionate is predicted to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
