Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 212-782-2 | CAS number: 868-77-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is found to be readily biodegradable and the applied test concentrations are in the range of concentrations that can be expected in the influent of a sewage treatment plant
Reference
Description of key information
Toxicity to microorganisms testing is waived for 2-hydroxyethyl methacrylate since it is classified as readily biodegradable at an application concentration (100 mg/L) which is greater than the predicted environmental concentration (PEC) in the influent of the sewage treatment plant (STP).
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
The substance (2-hydroxyethyl methacrylate) was readily biodegradable in an OECD 301 C (MITI-test) at an application concentration (100 mg/L) which is greater than the predicted environmental concentration (PEC) in the influent of the sewage treatment plant (STP). According to Column 2 of REACH Annex VIII requirements, toxicity to microorganisms testing does not need to be conducted if the substance is readily biodegradable and the applied test concentrations are in the range of concentrations that can be expected in the influent of a sewage treatment plant. Hence, toxicity to microorganisms testing can be waived for 2-hydroxyethyl methacrylate. The PNEC STP was derived from the available ready biodegradation test data (MITI, OECD 301C).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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