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EC number: 202-708-7 | CAS number: 98-86-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Additional information on environmental fate and behaviour
Administrative data
- Endpoint:
- additional information on environmental fate and behaviour
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: study documented in sufficient detail
Data source
Reference
- Reference Type:
- publication
- Title:
- Molecular probe techniques for the identification of reductants in sediments: Evidence for reduction of 2-chloroacetophenone by hydride transfer.
- Author:
- Smolen JM, Weber EJ, and Tratnyek PG
- Year:
- 1 999
- Bibliographic source:
- Environ Sci Technol 33, 440-445
Materials and methods
- Principles of method if other than guideline:
- The reduction of 2-chloroacetophenone was examined in anoxic sediment slurries from both freshwater and marine sources.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Acetophenone
- EC Number:
- 202-708-7
- EC Name:
- Acetophenone
- Cas Number:
- 98-86-2
- Molecular formula:
- C8H8O
- IUPAC Name:
- 1-phenylethanone
- Details on test material:
- - Name of test material (as cited in study report): acetophenone
- Substance type: aromatic ketone
- Physical state: liquid (mp: ca. 20°C)
- Analytical purity: >97%
- Impurities (identity and concentrations): not reported
Constituent 1
Results and discussion
Any other information on results incl. tables
The reduction of 2-chloroacetophenone (2 -CAP) was examined in anoxic sediment slurries from both freshwater and marine sources. Two reduction pathways of 2 -CAP were assumed:
a. hydride transfer to produce 2 -chloro-1 -phenyl ethanol and
b. electron transfer to produce acetophenone and subsequently sec.-phenylethyl alcohol.
Using freshwater sediment, 50% (fresh water pond, Cherokee Park) and 20% (Rock Creek) acetophenone was produced from 2 -CAP. In both marine sediments a 20% conversion each (Young's Bay and Institute Marsh) of 2 -CAP to acetophenone was observed. Acetophenone itself was further transformed by electron transfer to sec.-phenylethyl alcohol. Based on the observations made during temperature studies (conversion increased with increasing temperature), the authors concluded that the transformation of 2 -CAP to acetophenone and sec.-phenylethyl alcohol occurred mainly via abiotic reactions (metallocoenzyms).
Applicant's summary and conclusion
- Conclusions:
- In tests conducted using freshwater and marine sediments and anaerobic conditions, 2-CAP was transformed via electron transfer to acetophenone and subsequently to sec.-phenylethyl alcohol as could be determined via HPLC and GC/MS. Based on the temperature studies, the conversion of 2-CAP to acetophenone and subsequently sec.-phenylethyl alcohol occured via abiotic reactions (metallocoenzyms).
- Executive summary:
The reduction of 2-chloroacetophenone (2 -CAP) was examined in anoxic sediment slurries from both freshwater and marine sources. Two reduction pathways of 2 -CAP were assumed:
a. hydride transfer to produce 2 -chloro-1 -phenyl ethanol and
b. electron transfer to produce acetophenone and subsequently sec.-phenylethyl alcohol.
Using freshwater sediment, 50% (fresh water pond, Cherokee Park) and 20% (Rock Creek) acetophenone was produced from 2 -CAP. In both marine sediments a 20% conversion each (Young's Bay and Institute Marsh) of 2 -CAP to acetophenone was observed. Acetophenone itself was further transformed by electron transfer to sec.-phenylethyl alcohol. Based on the observations made during temperature studies (conversion increased with increasing temperature), the authors concluded that the transformation of 2 -CAP to acetophenone and sec.-phenylethyl alcohol occurred mainly via abiotic reactions (metallocoenzyms).
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