Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-708-7 | CAS number: 98-86-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Information on aerobic and anaerobic degradation of acetophenone are available. In the study conducted according to OECD Guideline 301C, acetophenone proved to be readily biodegradable and fulfilling the 14 d window criterion (64.7% biodegradation after 14 d). A number of supportive studies confirm this result obtained at the well-known stringent conditions of the MITI Test (very high ratio substance/inoculum). Under anaerobic conditions, acetophenone was biodegraded neither in the standard test nor in the low concentration test in appreciable amounts (general: 30% biodegradation after 28 d; in the low concentration test: 15% degradation after 28 d, value taken from a figure). Benzoic acid (reference substance) was biodegraded by more than 78% after 14 d.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The aerobic biodegradation was investigated in a study conducted according to OECD Guideline 301C ' Ready biodegradability: Modified MITI Test (I)' and judged as valid with restrictions due to some missing information. The study on the anaerobic biodegradation of acetophenone was judged as reliable with restrictions as the study is documented in sufficient detail and the methods applied meet generally accepted scientific principles.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
