Registration Dossier
Registration Dossier
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EC number: 202-996-4 | CAS number: 102-01-2
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Acetoacetanilide
- EC Number:
- 202-996-4
- EC Name:
- Acetoacetanilide
- Cas Number:
- 102-01-2
- Molecular formula:
- C10H11NO2
- IUPAC Name:
- 3-oxo-N-phenylbutanamide
- Details on test material:
- Acetessiganilid TTR Chargen-Nr.: C 332
Constituent 1
Study design
- Analytical monitoring:
- yes
- Buffers:
- KCl/HCl-Buffer at pH 1.5
- Details on test conditions:
- Methanol as vehicle is used for preparation of stock solution
Duration of test
- Duration:
- 167.5 h
- pH:
- 1.5
- Temp.:
- 37 °C
- Initial conc. measured:
- 209.3 mg/L
Results and discussion
- Transformation products:
- yes
Identity of transformation products
- No.:
- #1
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- aniline
- Inventory number:
- InventoryMultipleMappingImpl [inventoryEntryValue=EC 200-539-3]
- CAS number:
- 62-53-3
- Identity:
- Benzenamine
- Molecular formula:
- C6H7N
- Molecular weight:
- 93.126
- SMILES notation:
- Nc1ccccc1
- InChl:
- InChI=1/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
Total recovery of test substance (in %)open allclose all
- % Recovery:
- ca. 99.33
- pH:
- 1.5
- Temp.:
- 37 °C
- Duration:
- ca. 95.5 h
- % Recovery:
- ca. 96.46
- pH:
- 1.5
- Temp.:
- 37 °C
- Duration:
- ca. 167.5 h
Dissipation DT50 of parent compoundopen allclose all
- pH:
- 1.5
- Temp.:
- 37 °C
- DT50:
- ca. 160.8 d
- Remarks on result:
- other: linear regression
- pH:
- 1.5
- Temp.:
- 37 °C
- DT50:
- ca. 131.4 d
- Remarks on result:
- other: linear regression
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The substance is very stable in water
- Executive summary:
The substance is very stable in water and undergoes hydrolysis only very slowly.
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