Registration Dossier
Registration Dossier
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EC number: 260-828-5 | CAS number: 57583-34-3
Stability in organic solvents and identity of relevant degradation products
Administrative data
Link to relevant study record(s)
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: 98/8/EC IIIA, III 2
- Deviations:
- no
- GLP compliance:
- yes
- Test substance stable:
- yes
- Transformation products:
- not measured
- Conclusions:
- The test material is stable as a nominal 10 g/l solution in Diethyl Ether for at least 32 days at 25 ± 2 °C. The test material undergoes an approximately 10 % reduction in concentration during the first 14 days of storage at 25 ± 2 °C as a 10 g/l solution in Tetrahydrofuran with no further significant change in concentration for the next 18 days of storage at 25 ± 2 °C. As the results indicate that the test material reached a stable concentration during the storage period, the approximate 10% reduction is not regarded as significant.
- Executive summary:
The stability of the test material has been determined in two organic solvents in accordance with Council Directive 98/8/EC, Annex III. The test material is stable as a nominal 10 g/l solution in Diethyl Ether for at least 32 days at 25 ± 2 °C.
The test material undergoes an approximately 10 % reduction in concentration during the first 14 days of storage at 25 ± 2 °C as a 10 g/l solution in Tetrahydrofuran with no further significant change in concentration for the next 18 days of storage at 25 ± 2 °C. As the results indicate that the test material reached a stable concentration during the storage period, the approximately 10 % reduction is not regarded as significant.
Reference
Description of key information
Stability in organic solvents: Results indicate that the test material reached a stable concentration during the storage period.
Additional information
The stability of the test material has been determined in two organic solvents in accordance with Council Directive 98/8/EC, Annex III. The test material is stable as a nominal 10 g/L solution in Diethyl Ether for at least 32 days at 25 ± 2 °C.
The test material undergoes an approximately 10 % reduction in concentration during the first 14 days of storage at 25 ± 2 °C as a 10 g/l solution in Tetrahydrofuran with no further significant change in concentration for the next 18 days of storage at 25 ± 2 °C. As the results indicate that the test material reached a stable concentration during the storage period, the approximately 10 % reduction is not regarded as significant.
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