Registration Dossier
Registration Dossier
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EC number: 203-941-7 | CAS number: 112-16-3
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound lauroyl chloride and hydrolysis product lauric acid: Adsorption to solid soil phase is expected at pH <= 7. Adsorption tosolid soil phase is not expected at pH > 7.
Key value for chemical safety assessment
Additional information
A study is not required for this tonnage band.
Parent compound lauroyl chloride:
The adsorption potential of lauroyl chloride (CAS 112 -16 -3) was calculated using EPI Suite v.4.10. The estimates for the uncharged molecule using the MCI and the Kow method of the KOCWIN v2.00 module from SRC EPI Suite v4.10 are listed below.
Lauroyl chloride (CAS 112 -16 -3) rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and lauric acid (CAS 143 -07 -7).
Therefore, the model calculation may be of low relevance.
Uncharged molecule:
- MCI method: Koc = 335; log Koc = 2.5
- Kow method: Koc = 1418; log Koc = 3.2
Based on the MCI method of the uncharged molecule, adsorption to solid soil phase is not expected.
Hydrolysis compound lauric acid:
The adsorption potential was estimated for lauric acid (143 -07 -7) using the MCI and the Kow methods of the KOCWIN v2.00 module from SRC EPI Suite v4.10. These estimates are representative for uncharged molecules. The substance ionises in aqueous solutions, therefore the adsorption coefficient was calculated according to Franco & Trapp (2008) as well as according to the REACH Guidance (2008) to correct for the charged molecule at pH 5, 7, 8 and 9. The Koc values are listed below.
Uncharged molecule:
- MCI method: Koc = 319; log Koc = 2.5
- Kow method: Koc = 501; log Koc = 2.7
Charged molecule:
- Franco & Trapp, 2008:
pH 5: Koc = 4501; log Koc = 3.65
pH 7: Koc = 4501; log Koc = 3.65
pH 8: Koc = 137; log Koc = 2.14
pH 9: Koc = 124; log Koc = 2.09
Based on the corrections for the charged molecule according to Franco & Trapp (2008), adsorption to the solid soil phase is expected at pH 7 and lower. At pH values above 7, adsorption to solid soil phase is not expected. Moreover, lauric acid is considered to be readily biodegradable.
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