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Diss Factsheets

Physical & Chemical properties

Density

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from may 19, 2011 to july 12, 2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
2010-12-15
Type of method:
air comparison pycnometer (for solids)
Key result
Type:
relative density
Density:
1.307
Temp.:
20.6 °C

Assay No. 1

 

Test item sample weight

4.3989

 g

Reference volume (VA)

 

79.330

 cm3

Volume of sample cell holder

33.071

 cm3

Temperature during the assay

20.6

 °C

 

Data

P2 (PSIG)

P3 (PSIG)

VP (cm3)

Mean density (g/cm3)

Mean relative density

Run No. 1

17.022

4.638

3.3607

1.3089

1.308

 

0.001

Run No. 2

17.039

4.642

3.3662

1.3068

±

Run No. 4

17.035

4.641

3.3655

1.3071

 

Remark: The run No. 3 was not taken into account, it was not complying the quality criteria.

 

Assay No. 2

 

Test item sample weight

4.2985

 g

Reference volume (VA)

 

79.330

 cm3

Volume of sample cell holder

33.071

 cm3

Temperature during the assay

20.5

 °C

 

Data

P2 (PSIG)

P3 (PSIG)

VP (cm3)

Mean density (g/cm3)

Mean relative density

Run No. 1

17.035

4.649

3.295

1.3045

1.305

 

0.001

Run No. 2

17.046

4.652

3.295

1.3045

±

Run No. 4

17.037

4.650

3.291

1.3061

 

Remark: The run No. 3 was not taken into account, it was not complying the quality criteria.

Conclusions:
The relative density mean value of the test item using the gas comparison method with the stereopycnometer was D (20.6°C / 4°C) = 1.307 ± 0.002
Executive summary:

In a GLP study (Défitraces, 2011), the relative density of Ethylvanillin was determined using the gas comparison pycnometer, according to the OECD 109 guideline.

The relative density mean value of the test item was D (20.6°C / 4°C) = 1.307 ± 0.002.

Description of key information

The determined density was 1.307

Key value for chemical safety assessment

Relative density at 20C:
1.307

Additional information

Only one GLP study, OECD 109 compliant, was available and was selected as key study. It was quoted with reliability 1 according to Klimisch scale.