Registration Dossier
Registration Dossier
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EC number: 231-842-9 | CAS number: 7758-89-6
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, GLP.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Reference Type:
- secondary source
- Title:
- SIDS Copper Monochloride CAS: 7758-89-6, final Oct 2006
- Author:
- OECD
- Year:
- 2 006
- Bibliographic source:
- UNEP Publications
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Copper monochloride
- IUPAC Name:
- Copper monochloride
- Reference substance name:
- Copper chloride
- EC Number:
- 231-842-9
- EC Name:
- Copper chloride
- Cas Number:
- 7758-89-6
- Molecular formula:
- Cl Cu
- IUPAC Name:
- λ¹-copper(1+) chloride
- Details on test material:
- Analytical purity: 97 %
Sigma-Aldrich Corporation, Lot. No. 17119BO
Constituent 1
Constituent 2
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): DMSO
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea
- Strain: not stated
- Source: GSF Institute of Ecological Chemistry, Germany
- Age at study initiation: Juveniles within 24 hours old
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 243 mg/L as CaCO3
- Test temperature:
- 20.1 ± 0.4 °C
- pH:
- 7.85 - 8.02
- Dissolved oxygen:
- 8.7 - 9.4 mg/L (96 - 103 %)
- Nominal and measured concentrations:
- Nominal concentration: control, solvent control, 0.2, 0.3, 0.6, 1.0, 1.7, and 2.8 mg/L.
Mean measured concentration: control, solvent control, 0.09, 0.18, 0.42, 0.74, 1.29, and 1.98 mg/L - Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 3
- No. of vessels per control (replicates): 3
- No. of vessels per vehicle control (replicates): 3
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: OECD M4 medium
OTHER TEST CONDITIONS
- Photoperiod: 16/8 (light/dark)
- Light intensity: 598 - 632 Lux
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.25 mg/L
- Nominal / measured:
- meas. (not specified)
- Basis for effect:
- mobility
Any other information on results incl. tables
Exposure time 24 hrs 48 hrs
------------------------------------------------
EC50 0.33 0.25
LC0 - -
LC100 0.74 0.74
NOEC - -
------------------------------------------------
Applicant's summary and conclusion
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