Registration Dossier
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EC number: 263-005-9 | CAS number: 61788-78-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In a reliable guideline study, the 21day NOEC was 6.8 and 99.1 μg a.i./L ( i.e., 0.0068 and 0.0991 mg a.i./L) in Southwest well and river water, respectively for the read-across substance C16-C18 and C18 unsat., TMAC.
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater invertebrates:
- 0.007 mg/L
Additional information
In an OECD 211 study, the effect of the read-across substance C16-C18 and C18 unsat TMAC on the short term (21-day) toxicity and reproduction of Daphnia magna was evaluated. Daphnia magna were exposed to six concentrations of the test substance in a 21-day static-daily renewal test in three different water types (i.e., laboratory blended water, Southwest well water and river water). Analytical determination of the test substance was performed. Measured concentrations (μg/L; values represent the geometric mean of the 0- and 24-h concentration analyses) were: Southwest well water: 1.6, 3.1, 6.8, 14.6, 30.6 and 60.8 μg a.i./LRiver water: 35.7, 53.4, 68.3, 99.1, 122.3 and 309.3 μg a.i./L. The test in blended water was discontinued after 14 days due to inadequate reproduction by control organisms. The mortality was monitored daily and the number of young produced in each beaker was recorded. Test substance concentrations were verified by analysis and represent the geometric mean of the 0 and 24-hour concentration. Under the test conditions, the 21-day NOEC of the test substance was found to be 6.8 and 99.1 μg/L (i.e., equivalent to 0.0068 and 0.099 mg a.i./L) in Southwest well and river water, respectively. The number of days until the first reproduction was similar across all groups within the Southwest well water group and river water group (i.e., 11 days and 8 - 9 days, respectively) (Valentine and Bishop, 1992).
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