Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name:
  • IUPAC name: 2-(2-{[2-(oxiran-2-ylmethoxy)phenyl]methyl}phenoxymethyl)oxirane; 2-(2-{[4-(oxiran-2-ylmethoxy)phenyl]methyl}phenoxymethyl)oxirane; 2-(4-{[4-(oxiran-2-ylmethoxy)phenyl]methyl}phenoxymethyl)oxirane
  • Substance names and other identifiers
EC / List no.:
500-006-8
CAS no.:
9003-36-5
Index number:
Molecular formula:
C57H60O12
SMILES:
C(OC1=CC=C(CC2=CC=C(OCC3CO3)C=C2)C=C1)C1CO1.C(OC1=CC=C(CC2=C(OCC3CO3)C=CC=C2)C=C1)C1CO1.C(OC1=CC=CC=C1CC1=CC=CC=C1OCC1CO1)C1CO1
InChI:
InChI=1/3C19H20O4/c1-5-16(20-10-18-12-22-18)6-2-14(1)9-15-3-7-17(8-4-15)21-11-19-13-23-19;1-3-7-18(22-12-16-10-20-16)14(5-1)9-15-6-2-4-8-19(15)23-13-17-11-21-17;1-2-4-19(23-13-18-12-22-18)15(3-1)9-14-5-7-16(8-6-14)20-10-17-11-21-17/h1-8,18-19H,9-13H2;1-8,16-17H,9-13H2;1-8,17-18H,9-13H2
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
2
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
NLP (No-Longer Polymers) List

Hazard classification & labelling

Warning! According to the classification provided by companies to ECHA in CLP notifications this substance is toxic to aquatic life with long lasting effects, causes serious eye irritation, causes skin irritation and may cause an allergic skin reaction.

Breakdown of all 806 C&L notifications submitted to ECHA

Aquatic Chronic 2 H411
Skin Irrit. 2 H315
Skin Sens. 1 H317
Eye Irrit. 2 H319
Aquatic Chronic 4 H413
Not Classified
Acute Tox. 3 H311
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (84.89% of CLP notifications).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 1 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100+ tonnes per year.

This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

This substance is used in the following products: coating products and fillers, putties, plasters, modelling clay.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: formulation of mixtures and/or re-packaging and building & construction work. This substance is used for the manufacture of: plastic products, mineral products (e.g. plasters, cement), fabricated metal products, electrical, electronic and optical equipment and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals at non-dedicated facilities, closed, continuous processes with occasional controlled exposure, roller or brushing applications, non-industrial spraying and hand mixing with intimate contact only with personal protective equipment available.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: mixing in open batch processes and transfer of chemicals at dedicated facilities.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: chemicals, plastic products, fabricated metal products, electrical, electronic and optical equipment and machinery and vehicles.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, transfer of substance into small containers, mixing in open batch processes, closed, continuous processes with occasional controlled exposure, calendering operations and industrial spraying.

Release to the environment of this substance can occur from industrial use: in the production of articles.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Harke Services GmbH-OR3, Xantener Str.1 45479 Mülheim an der Ruhr Germany
  • Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7 2260 Westerlo Belgium

Substance names and other identifiers

Formaldehyde, oligomeric reaction products with 1-chloro-2,3-epoxypropane and phenol
EC Inventory, Substance Evaluation - CoRAP, REACH pre-registration
Formaldehyde, polymer with 2-(chloromethyl)oxirane and phenol
Other
2-(2-{[2-(oxiran-2-ylmethoxy)phenyl]methyl}phenoxymethyl)oxirane; 2-(2-{[4-(oxiran-2-ylmethoxy)phenyl]methyl}phenoxymethyl)oxirane; 2-(4-{[4-(oxiran-2-ylmethoxy)phenyl]methyl}phenoxymethyl)oxirane
C&L Inventory, Other
2-(chloromethyl)oxirane; formaldehyde; phenol
C&L Inventory
Bisphenol F-Epoxidharz
C&L Inventory
bisphenol-F-epichlorohydrin resin, MM=<700
C&L Inventory
Bisphenol-F-Epoxidharz
C&L Inventory
Epichlorohydrin formaldehyde-phenol polymer; epoxy resin
C&L Inventory
Epoxy Phenol Novolac Resin
C&L Inventory
epoxy phenol novolak resin: Phenol, polymer with formaldehyde, glycidyl ether or Epichlorohydrin-formaldehyde-phenol copolymer OR Formaldehyde, oligomeric reaction products with 1-chloro-2,3-epoxypropane and phenol
C&L Inventory
EPOXY RESIN
C&L Inventory
Formaldehyde
C&L Inventory
Formaldehyde, olgomeric reaction products with 1-chloro-2,3epoxypropane and phenol
C&L Inventory
FORMALDEHYDE, OLIGOMERIC REACTION PRODUCTS WITH 1-CHLORO-2,3- EPOXYPROPANE AND PHENOL
C&L Inventory
Formaldehyde, Oligomeric reaction products with 1-chloro2,3-epoxypropane and phenol
C&L Inventory
Formaldehyde, polymer with (chloromethyl)oxirane and phenol
C&L Inventory
Formaldehyde, polymer with (chloromethyl)oxirane and phenol;
C&L Inventory
formaldehyde,oligomeric reaction products with 1-chloro-2,3-epoxypropane and phenol
C&L Inventory
Phenol condensation products, with 1-chloro-2,3-epoxypropane and
C&L Inventory
Phenol condensation products, with 1-chloro-2,3-epoxypropane and formaldehyde
Registration dossier
Phenol, polymer with formaldehyde, glycidyl ether
C&L Inventory
Reaction mass of 2,2'-[methylenebis(p-phenyleneoxymethylene)]bisoxirane and 2,2'-[methylenebis(o-phenyleneoxymethylene)]bisoxirane and [[2-[p-(oxiranylmethoxy)benzyl]phenoxy]methyl]oxirane
C&L Inventory
Resina epossidica a base bisfenolo
C&L Inventory
18EN
C&L Inventory
Araldite GY 282; 100% Active Matter; active substance
C&L Inventory
Araldite GY 285
C&L Inventory
Bakelite EPR 600 X 80; 80:20
C&L Inventory
Bakelite EPR 600; MG≤700
C&L Inventory
Epichlorohydrin-formaldehyde-phenol copolymer
C&L Inventory
Epichlorohydrin-formaldehyde-phenol polymer
C&L Inventory
Epichlorohydrin-phenol-formaldehyde epoxy novolak resin
C&L Inventory
Epichlorohydrin-phenol-formaldehyde polymer
C&L Inventory
Epichlorohydrin-phenolformaldehyde resin
C&L Inventory
Epiclon EXA 830 CRP; MG≤700; 100% Active Matter; active substance
C&L Inventory
Epikote 806 L
C&L Inventory
EPOTEC YDF 170
Registration dossier
EPOTEC YDF 170 LC
Registration dossier
EPOTEC YDF 171
Registration dossier
EPOTEC YDF 173
Registration dossier
ERRE 0100
C&L Inventory
Formaldehyde-phenol-epichlorohydrin copolymer
C&L Inventory
Oxirane, (chloromethyl)-, polymer with formaldehyde and phenol
C&L Inventory
Phenol, polymer with (chloromethyl)oxirane and formaldehyde
C&L Inventory
Propane, 1-chloro-2,3-epoxy-, polymer with formaldehyde and phenol
C&L Inventory
RE 304 S
C&L Inventory
RE 403 S
C&L Inventory
RE 404 S; 100% Active Matter; active substance
C&L Inventory
RUETAPOX 0300; MG≤700
C&L Inventory
Rütapox 0300 X 80; 80:20
C&L Inventory
Rütapox 300; MG≤700
C&L Inventory
XD 7230
C&L Inventory
XD 7855
C&L Inventory
Formaldehyde, polymer with (Chloromethyl) Oxirane and phenol.
REACH pre-registration
1332896-14-6
Deleted CAS number
Other
39342-30-8
Deleted CAS number
Other
86159-38-8
Deleted CAS number
Other
9003-36-5
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Registration dossier, REACH pre-registration, Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Data not provided by the registrant

Melting/freezing point

Data not provided by the registrant

Boiling point

Data not provided by the registrant

Density

Data not provided by the registrant

Vapour pressure

Data not provided by the registrant

Partition coefficient

Data not provided by the registrant

Water solubility

Data not provided by the registrant

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Data not provided by the registrant

Flash point

Data not provided by the registrant

Auto flammability

Data not provided by the registrant

Flammability

Data not provided by the registrant

Explosiveness

Data not provided by the registrant

Oxidising

Data not provided by the registrant

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Data not provided by the registrant

Viscosity

Data not provided by the registrant

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Data not provided by the registrant

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Data not provided by the registrant

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Data not provided by the registrant

Bioaccumulation: aquatic / sediment

Data not provided by the registrant

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Data not provided by the registrant

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

Data not provided by the registrant

Short–term toxicity to fish

Data not provided by the registrant

Long–term toxicity to fish

Data not provided by the registrant

Short–term toxicity to aquatic invertebrates

Data not provided by the registrant

Long–term toxicity to aquatic invertebrates

Data not provided by the registrant

Toxicity to aquatic algae and cyanobacteria

Data not provided by the registrant

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Data not provided by the registrant

Sediment toxicity

Data not provided by the registrant

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Data not provided by the registrant

Toxicity to terrestrial arthropods

Data not provided by the registrant

Toxicity to terrestrial plants

Data not provided by the registrant

Toxicity to soil microorganisms

Data not provided by the registrant

Toxicity to birds

Data not provided by the registrant

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

Data not provided by the registrant

Toxicokinetics, metabolism, and distribution

Data not provided by the registrant

Acute toxicity

Data not provided by the registrant

Irritation / corrosion

Data not provided by the registrant

Sensitisation

Data not provided by the registrant

Repeated dose toxicity

Data not provided by the registrant

Genetic toxicity

Data not provided by the registrant

Carcinogenicity

Data not provided by the registrant

Toxicity to reproduction

Data not provided by the registrant

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant