Registration Dossier
Registration Dossier
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EC number: 219-754-9 | CAS number: 2524-03-0
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: other: No data
- Type of information:
- other: Article
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- IUCLID Dataset
- Author:
- European Commission; European chemicals Bureau
- Year:
- 2 000
- Bibliographic source:
- European Commission; European chemicals Bureau
- Report date:
- 2000
Materials and methods
- Principles of method if other than guideline:
- No data given
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- O,O-dimethyl phosphorochloridothioate
- EC Number:
- 219-754-9
- EC Name:
- O,O-dimethyl phosphorochloridothioate
- Cas Number:
- 2524-03-0
- Molecular formula:
- C2H6ClO2PS
- IUPAC Name:
- O,O-dimethyl chlorophosphonothioate
Constituent 1
Method
- Target gene:
- No data
Species / strain
- Species / strain / cell type:
- S. typhimurium, other: no further info
- Additional strain / cell type characteristics:
- not specified
- Metabolic activation:
- not specified
- Test concentrations with justification for top dose:
- 0.014-50 ul/plate
Results and discussion
Test results
- Species / strain:
- S. typhimurium, other: no further info
- Metabolic activation:
- with and without
Any other information on results incl. tables
Result: negative
No information on: genotoxicity and cytotoxicity.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
There is weight of evidence that the substance is non-toxic towards genes
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