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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 November 2019 to 30 March 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
2009
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
2006
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Specific details on test material used for the study:
Purity: 94.5 %
Storage Condition: Ambient temperature, cool and dry conditions, DEFITRACES.
Key result
Test no.:
#1
Temp.:
ca. 20 °C
Vapour pressure:
ca. 0.002 Pa

The mass of sample weighed for each assay was reported in the table below. The sample was placed in a Knudsen effusion cell. Then the cell was placed in the apparatus.

Assay

No.

Test temperature

t (°C)

Mass of test item

(mg)

Knudsen

effusion cell

aperture size

(μm)

Result used

1

43

14.34

279.9

Yes

2

38

14.34

279.9

Yes

3

30

14.34

279.9

Yes

4

25

14.34

279.9

Yes

No degradation of the test item was observed.

 

Conclusions:
3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole is a solid at 20°C with a vapour pressure of 1.845 x 10-3 Pa at 20 °C.
Executive summary:

By dynamic effusion method with a micro-balance vapour pressure for 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole was evaluated according to OECD guideline 104 (2006) and EC A.4 (2009).

The vapour pressure (P) of the test item extrapolated is 1.845 x 10-3 Pa at 20 °C.

The volatility (H) of the test item calculated at 20 °C is 5.549 x 10-4 Pa.m3.mol-1.

Description of key information

In compliance with Regulation (EC) No. 1907/2006, Council Regulation (EC) No. 761/2009, EC A.4. method (2009) and OECD Guideline No. 104 (2006), the vapour pressure (P) of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole extrapolated is 1.845 x 10-3 Pa at 20 °C.

The volatility (H) of 3-Bromo-1-(3-Chloro-2-Pyridyl)-5-Methyl-1H-Pyrazole calculated at 20 °C is 5.549 x 10-4 Pa.m3.mol-1.

Key value for chemical safety assessment

Vapour pressure:
0.002 Pa
at the temperature of:
20 °C

Additional information