Mecoprop

Boiling point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

15 April 1999 to 23 June 1999

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method according to Siwoloboff

Key result

Atm. press.:

1 017 mBar

Decomposition:

yes

Decomp. temp.:

> 260 °C

- Barometric pressure: 1017 mbar
- As the temperature increased, the sample was observed to darken at 260 °C and then turn an amber colour, indicating decomposition.

Conclusions:

Under the conditions of the study, the boiling point of the test material was not determinable, as the test material decomposed at temperatures above 260 °C without boiling.

Executive summary:

The boiling point of the test material was investigated in accordance with the standardised guideline OECD 103, under GLP conditions.

A boiling tube (3.2 mm diameter) was filled with the sample and heated until liquid. A boiling capillary was then immersed, open end first. Observations were then recorded as the temperature of the sample was raised.

Under the conditions of the study, the boiling point of the test material was not determinable, as the test material decomposed at temperatures above 260 °C without boiling.

Reference 2

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

24 January 1991 to 29 April 1991

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

GLP compliance:

yes (incl. QA statement)

Type of method:

other: Capillary Tube method

Boiling pt.:

ca. 266.9 °C

Atm. press.:

ca. 760 mm Hg

Decomposition:

no

The results of duplicate boiling point determinations on the test material, at an atmospheric pressure of 772.50 mm Hg, were as follows:

 

Test Material Results

	Temperature (°C)
	Run I	Run II
T’	265	267
Tp	264.2	266.2
Tp’	265.9	267.9

Where Tp' is the measured boiling point corrected for pressure (at 760 mm Hg) and then inserted into the linear regression.

 

Thus, the boiling point of the test material is 266.9 °C (539.9 K) (mean of 265.9 and 267.9 °C).

Conclusions:

Under the conditions of this study, the boiling point of the test material was determined to be 266.9 °C .

Executive summary:

The boiling point of the test material was investigated in accordance with the standardised guidelines OECD 103 and EU Method A2, under GLP conditions.

The boiling point determination was attempted by a capillary tube method using a Buchi 530 melting/boiling point apparatus to provide heating. The boiling points of several reference materials were determined to calibrate the apparatus and provide a correction to the measured boiling temperatures by inserting the measured values into the linear regression.

The results of duplicate boiling point determinations on the test material, at an atmospheric pressure of 772.50 mm Hg, were corrected for pressure (at 760 mm Hg) to give 265.9 and 267.9°C, resulting in a mean boiling point of 266.9°C.

Under the conditions of this study, the boiling point of the test material was determined to be 266.9 °C.

Description of key information

Key Study: Comb (2000)

Under the conditions of the study, the boiling point of the test material was not determinable, as the test material decomposed at temperatures above 260 °C without boiling.

Supporting Study: Cowlyn (1993)

Under the conditions of this study, the boiling point of the test material was determined to be 266.9 °C.

Key value for chemical safety assessment

Temperature of decomposition (state purity):

260 °C

Additional information

Key Study: Comb (2000)

The boiling point of the test material was investigated in accordance with the standardised guideline OECD 103, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

A boiling tube (3.2 mm diameter) was filled with the sample and heated until liquid. A boiling capillary was then immersed, open end first. Observations were then recorded as the temperature of the sample was raised.

Under the conditions of the study, the boiling point of the test material was not determinable, as the test material decomposed at temperatures above 260 °C without boiling.

 

Supporting Study: Cowlyn (1993)

The boiling point of the test material was investigated in accordance with the standardised guidelines OECD 103 and EU Method A2, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

The boiling point determination was attempted by a capillary tube method using a Buchi 530 melting/boiling point apparatus to provide heating. The boiling points of several reference materials were determined to calibrate the apparatus and provide a correction to the measured boiling temperatures by inserting the measured values into the linear regression.

The results of duplicate boiling point determinations on the test material, at an atmospheric pressure of 772.50 mm Hg, were corrected for pressure (at 760 mm Hg) to give 265.9 and 267.9°C, resulting in a mean boiling point of 266.9°C.

Under the conditions of this study, the boiling point of the test material was determined to be 266.9 °C.