Registration Dossier
Registration Dossier
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EC number: 204-706-1 | CAS number: 124-63-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Skin irritation
A limited study performed with the “mouse tail method” indicate that methanesulfonyl chloride is corrosive (Latven, 1976).
Eye irritation
0.1 ml of methanesulfonyl chloride (purity unknown) was placed in the conjunctival sac of one of each of 3 rabbits (Latven, 1977). The resulting reactions were scored for 7 days.All animals screamed in pain following instillation. Opacification of the cornea completely obscured the iris and the conjunctivae became necrotic white (dead) without chemosis. These effects appeared promptly and remained unaltered thereafter.
Effects on skin irritation/corrosion: corrosive
Effects on eye irritation: corrosive
Justification for classification or non-classification
Self-classification according to:
- Directive 67/548/EEC
R34 Causes burns.
- Regulation (EC) No 1272/2008
Skin corrosion/irritation, category 1B
serious eye damage/eye irritation, category 1
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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