Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-924-4 | CAS number: 111-96-6
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The long-term toxicity test to invertebrates revealed a NOEC of 320 mg/L for D. magna. In addition, the US EPA ECOSAr QSAR predicts for Diglyme a LC 50, 96 h, fish of ca. 15787 mg/L. Assuming that the chronic fish toxicity would be by a factor of 10 lower than the LC 50, 96 h this would lead to a chronic NOEC fish for Diglyme of 1579 mg/L. It is supported by US EPA ECOSAR estimation of the chronic NOEC fish of ca. 1392 mg/L which is regarded to be non-toxic. Based on the results of the long-term invertebrate study and the chronic QSAR result, a chronic fish test is not justified because of animal welfare reasons.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
