Registration Dossier
Registration Dossier
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EC number: 217-775-8 | CAS number: 1951-97-9
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is PBT / vPvB
- Justification:
Classification of piperazine, compound with phosphoric acid for effects in the environment
In determining the classification appropriate topiperazine, compound with phosphoric acid, it is necessary to consider all available evidence concerning its persistence, potential to accumulate and predicted or observed environmental fate and behaviour that may present a long-term and/or delayed danger to the structure and/or functioning of aquatic ecosystems. These points are considered below.
Persistence
Data is available to demonstrate thatpiperazine, compound with phosphoric acidis not persistent in the aquatic environment. However, it is persistent in the sediment environment but with no diffusion (0%) in the sediment compartment by virtue of which its persistence in the sediment environment can be considered to be non-critical. It is not persistent in the soil compartment based upon its half life and hence it has been concluded thatpiperazine, compound with phosphoric acidis not persistent in nature.
Thus,piperazine, compound with phosphoric acidis not classified as a persistent (P) chemical.
Potential to accumulate
The log Kow values forpiperazine, compound with phosphoric acidis less than 4 (Log Kow = -0.5316). The potential forpiperazine, compound with phosphoric acidto bioaccumulate in the tissues of organisms that inhabit aquatic or terrestrial matrices is negligible as the BCF factor for the substance is less than 1000.
The estimated BCF ofpiperazine, compound with phosphoric acidis highest 3.2 dimensionless and below the threshold of 2000.
Thus,piperazine, compound with phosphoric aciddoes not satisfy the criterion for classification as bioaccumulative (B).
The toxicity values of fish, invertebrates and algae are LC50 = 1000 mg/L, EC50 = 21 mg/L and EC50 =479.618 mg/L, respectively. The read across value of the parent chemical piperazine is suggesting classification in the Aquatic Chronic Category 3. Moreover, this chemical has a harmoinized classification in the Aquatic Chronic Category 3.
So,piperazine, compound with phosphoric acid satisfies the environmental effects criterion for classification as toxic (T).
Thus it can be inferred that piperazine, compound with phosphoric acidis not a P B but toxic chemical.
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