Registration Dossier
Registration Dossier
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EC number: 252-200-4 | CAS number: 34762-90-8
Endpoint summary
Administrative data
Description of key information
The estimated half-lives of the test substance at 25 °C was found to be 10.4, 10.3 and 10.4 for pH 4,7 and 9 respectively.
Additional information
AA study was conducted to evaluate the rate of hydrolysis of the test substance, trichloro(N,N dimethyloctylamine)boron according to the OECD Guideline 111 and EU Method C.7 in compliance with GLP. The study was conducted under dark conditions using three buffer solutions (Potassium hydrogen phthalate) Ph 4, (Disodium hydrogen orthophosphate) (anhydrous) pH 7, Disodium tetraborate Sodium chloride (pH 9). The three sample solutions were prepared in stoppered glass flasks at a nominal concentration of 3.0 x 10E-4 g/L in the corresponding three diluted buffer solutions. 1% v/v acetonitrile was used as co-solvent to aid solubility. The concentration of each solution did not exceed the lesser of 0.01 mol/L or half the estimated water solubility. The test solutions were split into individual vessels for each data point. The kinetics of the study have been determined to be consistent with that of a pseudo-first order reaction as the graphs of log10 concentration versus time are straight lines. It has been observed that the rate of hydrolysis does not change significantly within the pH range tested, i.e., from pH 4 to pH 9. Under study conditions, the estimated half-lives of the test substance at 25 °C was found to be 10.4, 10.3 and 10.4 for pH 4,7 and 9 respectively (Harlan, 2015).
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