Registration Dossier
Registration Dossier
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EC number: 205-451-9 | CAS number: 141-05-9
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only a table with results of the fish test is stated in this publication.
Data source
Reference
- Reference Type:
- publication
- Title:
- Fate of pesticides in the enviroment - a progress report
- Author:
- Billy Ray Wilson
- Year:
- 1 966
- Bibliographic source:
- Bureau of Conservation and Enviromental Science, Rutgers University, New Brunswick, N.J., Division of Enviromental Science
Materials and methods
Test guideline
- Deviations:
- not specified
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Diethyl maleate
- EC Number:
- 205-451-9
- EC Name:
- Diethyl maleate
- Cas Number:
- 141-05-9
- Molecular formula:
- C8H12O4
- IUPAC Name:
- diethyl (Z)-but-2-enedioate
- Details on test material:
- Compound: Dietyl maleate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test organisms
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- no data
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Post exposure observation period:
- no data
Test conditions
- Hardness:
- no data
- Test temperature:
- no data
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- not applicable
- Nominal and measured concentrations:
- no data
- Details on test conditions:
- no data
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- other: TLm
- Effect conc.:
- 41 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 41 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: The endpoint stated in the publication is a 96 hour TLm (median tolerance limit) which is the concentration resulting in 50 % survival after 96 hours exposure. This value corresponds to the more recent used 96 hours LC50 value.
- Details on results:
- no data
- Results with reference substance (positive control):
- no data
- Reported statistics and error estimates:
- no data
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 96 hour TLm (median tolerance limit = the concentration resulting in 50 % survival after 96 hours exposure) of Diethylmaleate was found to be 41 mg/L. The 96 hours TLm value corresponds to the more recent used 96 hours LC50 value. The fish species used was Pimephales promelas.
- Executive summary:
The 96 hour TLm (median tolerance limit = the concentration resulting in 50 % survival after 96 hours exposure) of Diethylmaleate was found to be 41 mg/L. The 96 hours TLm value corresponds to the more recent used 96 hours LC50 value. The fish species used was Pimephales promelas.
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