Brief Profile
Brief Profile
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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Brief Profile
The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.
Calcium dihydroxide
Brief Profile - Last updated: 21/08/2024 Print
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Sub. description
Substance description
Substance description
The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. By summarising this information in a single page, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards.
Data from all dossiers registered and the Classifications and Labelling Inventory (C&L) for the same substance are used to generate the Brief Profile. The information provided in the free-text fields is not published in the Brief Profiles.
The Brief Profile is automatically generated; information requirements under different legislative frameworks may, therefore, not be up-to-date or complete. For accuracy reasons, substance manufacturers and importers are responsible for consulting official sources. This Brief Profile is covered by the ECHA Legal Disclaimer.
Generating the Brief Profiles
The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility.
Due to the quantity of information and the number of chemicals, the Brief Profile is automatically generated based on the information available and is not manually verified. For sections such as substance use, chemical properties and the classification and labelling of substances, the quantity and quality of the information is the responsibility of manufacturers and importers. While the Agency tries to aggregate the information on chemicals in the best possible way, ECHA cannot check whether all the information provided by industry is free of errors.
Updates
Brief Profiles are updated regularly and new information is added when available. Since the source data can be updated at any time while the Brief Profiles are updated at intervals, a slight delay in the publication of information may occur.
The date of the last update corresponds to the publication date of the Brief Profile and not necessarily to the date in which the update occurred in the source data (registered dossiers, the C&L Inventory or a regulatory process).
Furthermore, updates in the source data may not always result in an update of the Brief Profile. For example, an update in a section of a dossier that is not displayed in the Brief Profile will not result in an update of the Brief Profile.
Dealing with Brief Profile errors
If you have any comments or suggestions, please contact ECHA using our contact form.
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Sci. properties
Scientific properties
Scientific properties
The ‘Scientific properties’ section gives an overview of summarised scientific data from registered dossiers. By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards.
All the source data on which the summaries on this page are based, is provided by industry and stored in the ECHA databases. Data from all dossiers registered for the same substance is used in the summarisation and aggregation process, as it is presumed that all data submitted by the registrants is relevant for the substance being registered. If the test material used is different from the substance being registered an indication will be provided. Please note that the information provided in the free-text fields is not published in the brief profiles.
Information in the ‘Scientific properties’ section is structured by substance properties, further broken down into endpoints. Each endpoint includes three information blocks:
- Study results – this information is collected from those endpoint study records provided by registrants of REACH dossiers which are flagged as Key or Weight of Evidence studies, and which have an indicated reliability (i.e. Klimisch score) of 1 or 2. Other types of studies are not processed for the Brief Profiles.
- Type of study provided – Provides an overview of the type of study records behind the presented results and data–waving justifications (e.g. key experimental study, Supporting QSAR study, etc.)
- Summary data – this information is collected from the endpoint summaries provided by registrants of REACH dossiers.
Note: Information presented in this section is generated as part of an automatic process, i.e. there is no manual verification or assessment of the correctness of the data. If no data is available in the registered substance dossiers, this will be indicated by a notification stating ‘Data not provided by the registrant’.
Summarisation and prioritisation of data
There are four methods to aggregate and summarise data, depending on the available data and endpoint. An icon is displayed to indicate the type of aggregation and summarisation performed:
- [R] Range of values – Range of results values (min-max) and range values of experimental condition(s) (min-max).
- [C] Concatenate distinct – Value types are ranked from most to least commonly provided, with a % attributed based on the count of total values provided.
- [M/C] Most conservative - Most conservative of all the data values provided, applying a precautionary principle (e.g. the lowest threshold or most hazardous statement)
- [P] Prioritisation – The result to be displayed is based on a set of criteria. For example, for endpoints related to (eco)toxicology four main types of criteria exist to prioritise the display of information: test species, dose descriptor, duration and measurement units. For Toxicology endpoint summaries two other criteria can be applied: Test type (Chronic, subchronic and subacute) and endpoint conclusion.
The precise data summarisation methods are specified per endpoint summary/study.
When more than one numerical result is available per endpoint the count is displayed between square brackets.
Units and data are normalised when possible and therefore the unit of measure/order of magnitude in the Brief Profile data may not correspond exactly to the one in the registered dossier. For temperature for example, data is standardised and displayed in Celsius (°C). For other data an order of magnitude logic might apply; e.g. 1 000 g will be displayed as 1 kg.
Processed studies and data-waiving
Due to the number of the substances and the associated information, substance data is processed and aggregated in an automatic process. Therefore, data has to fit the format and aggregation logic that is used for the Brief Profile.
Though the Agency aims to include as many studies as possible in the Brief Profile endpoint study results/summaries, those studies which do not fit the format or miss crucial information (such as measurement conditions) cannot be processed and therefore will not be included on this page. These study results can however be consulted when opening the source data.
The number of studies provided is indicated by ‘[x] studies submitted’, while the actual number of studies processed for the endpoint is indicated by ‘[x] studies processed’.
Data waiving
If only waived data is available for the substance, following justifications for data-waiving can be displayed in the Brief Profile:
- Study technically not feasible
- Study scientifically unjustified
- Exposure considerations
- Other justification
Excluded endpoints
Some endpoints are not included in the Brief Profile due to the use of free text and/or complex field(s) in the reporting of information, which cannot be easily summarised by an automatic algorithm. Please see the registered dossiers for substance information for the following endpoints:
- Particle size distribution
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- Additional physical-chemical information
- Mode of degradation in actual use
- Other distribution data
- Environmental data (monitoring data/field studies)
- Additional information on environmental fate and behaviour
- Toxicity to other aquatic organisms
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxicological information
- Skin irritation/corrosion (study results)
- Eye irritation (study results)
- Skin sensitisation (study results)
- Respiratory sensitisation (study results)
- Repeating dose toxicity oral/inhalation/dermal/other routes (study results)
- Toxicity to reproduction (study results)
- Developmental toxicity (study results)
- Toxicity to reproduction: other studies
- Specific investigations: other studies
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological information
Substance Description
Substance identity
The ’Substance identity’ section links substance identification information from all databases that are maintained by ECHA. The substance identifiers – if available and not claimed confidential – displayed in the ’Substance identity’ section of the Brief Profile are:
- EC name/number
- IUPAC name/number
- CAS number
- Index number
- Molecular formula
- Smiles
- InChI
In addition, information on the type of substance, origin, number and type of registered compositions and other places where the substance is listed are displayed in this section.
EC (European Community) name/number
The EC name and number are the official identifiers for substances within the European Union and can be found in the EC Inventory.
The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More information about the EC Inventory can be found here. If the substance has no EC number attributed, ECHA will attribute a list number. These numbers start with 6, 7, 8 or 9.
IUPAC name/number
An IUPAC name is based on the international standard chemical nomenclature set by the International Union of Pure and Applied Chemistry (IUPAC).
The IUPAC nomenclature is a systematic way of naming chemical substances, both organic and inorganic. In IUPAC nomenclature, prefixes, suffixes and infixes are used to describe the type and position of functional groups in the substance.
If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile.
See the official IUPAC website for more information on the International Union of Pure and Applied Chemistry.
CAS (Chemical Abstract Service) registry number
The CAS number is the substance numerical identifier assigned by the Chemical Abstract Service, a division of the American Chemical Society, to substances registered in the CAS registry database. A substance may have more than one CAS number associated. In this case, the preferred CAS number is displayed first. More about CAS and the CAS registry can be found here.
Index number
The Index number is the identification code given to substances in Part 3 of Annex VI to the CLP Regulation ((EC) No 1272/2008). A distinct classification and labelling corresponds to each Index number.
The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. ABC corresponds to the atomic number of the most characteristic element or the most characteristic organic group in the molecule. RST is the consecutive number of the substance in the series ABC. VW denotes the form in which the substance is produced or placed on the market. Y is the check-digit calculated in accordance with the 10-digit ISBN method.
Molecular formula
The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. If such information is available in ECHA’s database and is it not claimed confidential, the molecular formula and molecular structure will be displayed here.
SMILES
SMILES is the acronym for Simplified Molecular Input Line Entry Specification, a chemical notation system used to represent a molecular structure by a linear string of symbols.
With standard SMILES, the name of a molecule is synonymous with its structure: it indirectly shows a two dimensional picture of the molecular structure. Since a two dimensional chemical structure can be drawn in various ways, there are several correct SMILES notations for one molecule.
The basis of SMILES is the representation of a valence model of a molecule. SMILES notations are comprised of atoms (designated by elemental symbols), bonds, parentheses (used to show branching), and numbers (used for cyclic structures).
InChI
InChI is an abbreviated name for IUPAC International Chemical Identifier, a chemical identifier developed and supported by the InChI Trust.
InChIs consist of text strings comprising different layers and sublayers of information separated by slashes (/). Each InChI string starts with the InChI version number followed by the main layer. This main layer contains sublayers for the chemical formula, atom connections and hydrogen atoms. Depending on the structure of the molecule the main layer may be followed by additional layers e.g. for charge, stereo–chemical and/or isotopic information.
Molecular structure
Molecular structure displayed in this section is based on InChI annotation from IUCLID reference substances database and stored in the ECHA database. The structure is a computer generated visualisation of the molecular structure derived from the InChI character string.
Type of substance
Registrants can identify their substance as being a mono-constituent substance, multi-constituent substance, UVCB, polymer or specify another type. If more than one type of substance is registered, both types will be displayed.
Origin
Registrants can identify the origin of their substance as being:
- Element
- Inorganic
- Organic
- Organometallic
- Petroleum product
- Other
If more than one type of substance is registered, both types will be displayed.
Registered compositions (additives and impurities)
The total number of non-confidential registered compositions submitted in REACH dossiers are displayed here. If there are additives and impurities relevant for the substance classification, these are also indicated.
Within the context of REACH, impurities are unintended constituents present in a substance as manufactured. It may, for example, originate from the starting materials or be the result of secondary or incomplete reactions during the production process. While it is present in the final substance, it was not intentionally added. In most cases, impurities constitute less than 10% of the substance.
Additives are the constituents which have been intentionally added during the manufacturing process to stabilise the substance.
Substance listed
Provides information if the substance has been identified by one of the following previous EU chemicals regulatory frameworks:
- EINECS (European INventory of Existing Commercial chemical Substances) List
- ELINCS (European LIst of Notified Chemical Substances) List
- NLP (No-Longer Polymers) List
- EC / List name:
- IUPAC name: calcium dihydroxide
- Substance names and other identifiers
- EC / List no.:
- 215-137-3
- CAS no.:
- 1305-62-0
- Index number:
- Molecular formula:
- CaH2O2
- SMILES:
- [OH-].[OH-].[Ca++]
- InChI:
- InChI=1S/Ca.2H2O/h;2*1H2/q+2;;/p-2
- Type of substance:
- Mono constituent substance
- Origin:
- Inorganic
- Registered compositions:
- 78
- Of which contain:
- 42 impurities relevant for classification
- 0 additives relevant for classification
- Substance Listed:
- EINECS (European INventory of Existing Commercial chemical Substances) List
Hazard classification & labelling
The ‘Hazard classification and labelling’ section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under CLP (Classification Labelling and Packaging) Regulation. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH).
This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). The source of the information is mentioned in the introductory sentence of the hazard statement.
More information about classification and labelling can be found in the Regulations section of ECHA website.
Please note:
The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. It does not represent a new labelling, classification or hazard statement. Other relevant information includes the following:
- Substances may have impurities and additives that lead to different classifications. However, substance notifications in the Brief Profile are aggregated independently of the impurities and additives.
- Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or UN Global Harmonised System (GHS).
To see the full list of notified classifications and have more information on impurities and additives relevant to classification, you can consult the C&L Inventory.
Harmonised classification and labelling (CLH)
The Hazard classification and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Substance classifications under CLH are agreed at the Community level. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.
It is possible that the harmonisation is introduced through an amendment to the CLP Regulation. In that case, the ATP (Adaptation to Technical Progress) number is displayed. More information on CLH can be found here.
If the substance is classified under more than one CLH entry (e.g. disodium tetraborate EC no. 215–540–4, is covered by three harmonisations – 005–011–00–4; 005–011–01–1; 005–011–02–9), CLH information cannot be displayed in the Brief Profile as the differences between the CLH classifications require manual verification. If a substance is classified under multiple CLHs, a link to the C&L Inventory is provided to allow users to view CLH information manually, instead of having the information automatically generated in the Brief Profile.
Classification and labelling under REACH
Additional information on classification and labelling (C&L) – if available – is derived from REACH registration dossiers submitted by industry. This information has not been reviewed or verified by ECHA, and may change without prior notice. REACH registration dossiers have greater data requirements (support studies) than notifications under CLP. When submitted by the lead of a joint submission, the classifications may also reveal agreement between companies.
Notifications under the Classification, Labelling and Packaging (CLP) Regulation
If additional information derived from classification and labelling (C&L) notifications to ECHA under the CLP Regulation exists, this will be displayed below the information derived from harmonised classification and labelling and REACH registrations. These notifications can be provided by manufacturers, importers and downstream users. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information.
For readability purposes, only the pictograms, signal words and hazard statements referred to in more than 5% of the notifications under CLP are displayed.
Danger! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye damage, causes skin irritation and may cause respiratory irritation.
Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes severe skin burns and eye damage.
Breakdown of all 6627 C&L notifications submitted to ECHA
The chart displays the number of matching substance classifications (hazard class, categories and hazard statements) provided by manufacturers and importers under REACH and CLP notifications, as well as whether the substance is defined under harmonised classification and labelling (CLH).
The results of matching substance classifications are displayed in percentages of the total number of notifications. The bars indicate the number of matching classifications, i.e. the level of agreement, in substance classification between the REACH registrants (dark blue bar) and CLP notifiers (light blue bar), as well as between the notified classifications and the approved harmonised classification.
Harmonised classifications (√ - check mark)
- The (√- check mark)-icon indicates the classification is defined under harmonised classification and labelling (in accordance with the CLP Regulation) and made obligatory at Community level to ensure an adequate risk management throughout the European Community.
REACH & CLP classifications (bar)
- The dark blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in a REACH registration dossier. Classifications under REACH have to be supported by data (support studies).
- The light blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in CLP notifications.
Divergent classifications and impurities
The physical state and form of a substance can play a significant impact when the hazards of a substance are assessed. REACH and/or CLP notifiers may classify a substance differently based on different studies or the way they access the data.
For example, substance impurities can constitute a valid reason for a different classification of the substance. Different compositions or impurity profiles often lead to different classifications. If impurities and/or additives have been identified, an informative sentence is displayed below the graphic.
Different classifications can also be due to technical errors made during the notification process.
To have more information on impurities relevant to classification you can consult the C&L Inventory entry for the substance, or the disseminated registration dossier.
Harmonised Classification
REACH registration dossiers notifications
CLP notifications
At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.
Properties of concern
The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. The following properties have been highlighted as critical:
- C – This substance was identified as a carcinogenic (i.e. classified in Carcinogenicity categories 1A or 1B) in the EU harmonised classification and labelling and/or in a REACH registration dossier. More information about carcinogenicity here.
- M – This substance was identified as Mutagenic (i.e. classified in Mutagenicity categories 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about mutagenicity here.
- R – This substance was identified as toxic to reproduction (i.e. classified in reproductive toxicity categories 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about reproductive toxicity here.
- Ss – This substance was identified as a skin sensitiser (i.e. classified in skin sensitisation categories 1, 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about skin sensitiser here.
- Sr – This substance was identified as a respiratory sensitiser (i.e. classified in respiratory sensitisation categories 1, 1A or 1B) in the EU harmonised classification and labelling and/or by a REACH registration dossier. More information about respiratory sensitiser here.
- PBT – This substance was identified as persistent, bioaccumulative and toxic (PBT) by at least one REACH registrant (i.e. it is PBT/vPvB). More information about persistent, bioaccumulative and toxic substances here.
- POP – Recognised Persistent Organic Pollutant (POP): comes from an entry in the Annex I, II or III to the POPs Regulation and/or an entry in the Annex A, B or C to the Stockholm Convention. Under assessment as Persistent Organic Pollutant: is shown for substances that have been proposed for their inclusion in the Stockholm Convention and are under assessment, or for which a proposal is under preparation in the European Union. Note that proposals that have been set aside, either before their submission by the EU to the Convention, or by the POP Review Committee are still indicated as "Under assessment as POP".
The substance properties displayed in this section (with the exception of PBT properties) are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. In case the substance classification is not harmonised and the substance is not registered the properties are derived from classifications provided in CLP notifications. PBT properties are derived from REACH registered substances dossiers.
Critical property indentification: Where less than 90% of the notifiers provide the same classification to derive the critical property, the border of this critical property icon is displayed as dashed.
Impurities or additives: When a specific critical property is associated with compositions with impurities and/or additives, the respective critical property icon has a * associated.
Please note: The icons in this section are only meant as visual indicators to help communicate information about the abovementioned critical properties. Unlike the pictograms in the ‘Classification and Labelling’ section, these icons are not determined by any legislative procedure and have the sole purpose of being informative in the context of InfoCards and Brief Profiles.
Regulatory context
The ‘Regulatory context’ section provides an overview of the regulatory activities that are related to the substance. For general information about any of the different regulations which currently fall under ECHA’s mandate please see the links below.
Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
The REACH Regulation (1907/2006) entered into force on 1 June 2007. The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry.
The REACH regulatory processes identified for the Brief Profile are:
- Registration
- Pre-registration – indicated if the substance is included in the list of pre-registered substances. Pre-registration allows companies to continue manufacturing and importing their phase-in substances for several years until the registration deadline is reached.
- Registration – indicated if there is at least one dossier registered and disseminated for the substance, how many non-confidential registrations are active and/or inactive and the type of submissions (joint and/or individual).
- Evaluation
- Dossier evaluation – indicated if at least one registered dossier for the substance has been evaluated under REACH for compliance check or testing proposal evaluation and associated decision(s) published on the ECHA website.
- Substance evaluation – indicated if the substance is or was included in the Community rolling action plan (CoRAP). The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. After evaluation, proposals may be made for further regulatory action regarding the substance.
- Authorisation
- Candidate List – indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). The Candidate List includes substances that are subject to additional protocols and reporting obligations and which may eventually be included in the Authorisation list, further limiting their use.
- Authorisation list (Annex XIV) – indicates if the substance is included in the Authorisation List. These substances cannot be placed on the market or used after a given date, unless an authorisation is granted for their specific use, or the use is exempted from authorisation.
- Restriction
- Annex XVII (Restriction list) – indicates if the substance is included in the list of restrictions. The Restriction list describes the conditions for the manufacture, placing on the market or use of certain substances, either on their own or in mixtures or articles.
Persistent Organic Pollutants (POPs)
The POPs Regulation (EU) 2019/1021 entered into force on 15 July 2019, repealing the previous POPs Regulation (EC) No 850/2004. The regulation aims to protect human health and the environment by banning or severely restricting the production and use of persistent organic pollutants in the European Union.
The POPs regulatory processes identified for the Brief Profile are:
- List of substances subject to the POPs Regulation - Indicates if the substance is included in the POPs Regulation.
- List of substances proposed as POPs - Indicates if the substance has been proposed for its inclusion in the Stockholm Convention or if a proposal is under preparation in the European Union.
Classification, Labelling and Packaging (CLP)
The CLP Regulation (1272/2008) entered into force on 20 January 2009. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals.
The CLP regulatory processes identified for the Brief Profile are:
- Harmonised C&L– indicates if a European Union harmonised classifications and labelling has been assigned to the substance according to Annex VI to CLP and subsequent ATPs.
- Notification – indicates that notified C&L’s have been submitted to ECHA for a substance.
Biocidal Products Regulation (BPR)
The BPR (528/2012) entered into force on 1 September 2013. The BPR addresses the placing on the market and use of biocidal products, which are used to protect humans, animals, materials or articles against harmful organisms, like pests or bacteria, by regulating the active substances contained in a biocidal product.
The BPR regulatory processes identified for the Brief Profile are:
- Active substance approval – indicates if the substance is an approved biocidal active substance.
- Biocidal product authorisation – indicates if authorised biocidal products exist which use this substance as an active ingredient
Prior Informed Consent (PIC)
The PIC Regulation (649/2012) entered into force on 4 July 2014. PIC administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries.
The PIC regulatory processes identified for the Brief Profile are:
- Annex I – indicates if the substance is subject to PIC.
- Annex V – indicates if the substance is prohibited from export.
Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)
Registration
- Pre-registration:
- Substance pre-registered under REACH.
- Registration:
- This substance has 567 active registrations under REACH, 1 Joint Submission(s) and 3 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
- Dossier Evaluation:
- Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
- Substance Evaluation:
Authorisation
- Candidate List:
- Annex XIV (Authorisation List):
Restriction
- Annex XVII (Restriction List):
Persistent Organic Pollutants Regulation (POPs)
- List of substances subject to the POPs Regulation:
- List of substances proposed as POPs:
Classification Labelling & Packaging (CLP)
- Harmonised C&L:
- Seveso Annex I:
- Notified C&L:
- Classification & Labelling has been notified by industry to ECHA for this substance.
Biocidal Products Regulation (BPR)
- Active Substance:
- This substance is approved for use as a Biocidal Active Substance
- Biocidal Products:
Prior Informed Consent (PIC)
- Annex I:
- Annex V:
European Union Observatory for Nanomaterials (EUON)
- EUON:
About this substance
The ’About this substance’ section provides an overview of the volume in which this substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Data for calculating the ’total tonnage’ band is extracted from REACH registered dossiers for the last year reported on the tonnage manufactured or imported, unless the tonnage band has been claimed confidential. The ‘total tonnage’ band published does not necessarily reflect the registered tonnage band(s).
For more information on total tonnage band calculation please consult the Data submission manual.
Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. The information is aggregated from REACH registered dossiers provided by industry through a use descriptor system based on five separate descriptor lists which in combination with each other form a brief description of use and exposure for certain life cycle stage.
The use information is displayed per relevant life cycle stage of the substance.
- Manufacture stage includes processes by which the substance is manufactured from raw materials. Operations which are necessary for the handling of a substance on its own in the manufacturing for export or placing on the EU market are considered to be part of the manufacturing stage (e.g. filling into appropriate containers, storage or addition of stabiliser). If a substance is directly exported after manufacture, all activities with the substance will be reported under this stage.
- Formulation or re-packing stage corresponds to specific activities meant to produce a mixture to be placed on the market. This means that during formulation, the substance is transferred and mixed with other substances. It corresponds to activities taking place at industrial sites. This stage also includes chemical distributorsâ activities such as repacking (which involves transfer of the substance).
- End-use stage means the use of a substance as such or in a mixture (by professional workers (widespread uses), by consumers or at industrial sites), a last step before the end-of-life of the substance, namely before the substance is consumed in a process by reaction during use (including intermediate use), is emitted to waste streams or the environment or is included into an article.
- (Article) service life stage means the period of time a substance incorporated into an article remains in service or in use. Articles containing the substance can be used or processed by consumers, by workers at industrial sites and/or by professional workers. This also includes processing of semi-finished articles by workers with the aim of producing finished articles or repair and maintenance work like for example sanding of surfaces.
Use Descriptors
- The chemical product category (PC) describes the types of chemical products in which the substance is finally contained when it is supplied to end-users (by industrial, professional or consumer users). Examples include hydraulic fluids, perfumes and air care products. This category also describes uses as intermediate and under controlled conditions.
- The sector of use category (SU) describes in which sector of the economy the substance is used. This includes mixing or re-packing substances at the formulator’s level as well as industrial, professional and consumer end-uses (e.g. building and construction work or manufacture of food products).
- The process category (PROC) describes the application techniques or process types defined from the occupational perspective e.g. Industrial spraying, use in closed batch process (synthesis and formulation).
- The environmental release category (ERC) describes the broad conditions of use from the perspective of release to the environment (e.g. if the use occurs in industrial setting, if it is indoor use in long-life materials with a low release rate (e.g. flooring, furniture, toys, etc).
- The article category (AC) describes the type of article into which the substance has eventually been processed. This also includes mixtures in their dried or cured form (e.g. dried printing ink in newspapers; dried coatings on various surfaces).
Precautionary measures and safe use
This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. The recommendations are based on the precautionary statements provided in REACH registration dossiers.
If information on guidance on safe use is available in REACH registered dossiers, a link is displayed. Information in the guidance on safe use section consists of recommendations by a substance registrant(s) on the proper use of the substance in various situations. Examples include recommended measures on fire-fighting, transport, recycling and disposal.
More information on the use descriptor system can be found in ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment.Please note:
Only non-confidential use descriptors are displayed and for readability purpose only use descriptors occurring in more than 5% of the total occurrences are displayed.
For a detailed overview on identified uses and environmental releases, please consult the detailed information from the registration dossiers.
Use descriptors were adapted from ECHA guidance to improve readability and may not correspond textually to descriptor codes description as in ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment.
Precautionary measures and guidance on safe use concern the use and handling of the specific substance, not of the presence of the substance in other articles or mixtures.
This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 tonnes per annum.
This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
This substance is approved for use as a biocide in the EEA and/or Switzerland, for: disinfection, veterinary hygiene.
This substance is used in the following products: pH regulators and water treatment products, adsorbents, water treatment chemicals, fillers, putties, plasters, modelling clay, coating products, cosmetics and personal care products and fertilisers.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
This substance is used in the following activities or processes at workplace: hot work operations with metals (e.g. welding, soldering, gouging, brazing, flame cutting), production of mixtures or articles by tabletting, compression, extrusion or pelletisation, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding), the low energy manipulation of substances bound in materials or articles, open transfer and processing with minerals/metals at elevated temperature and potentially closed industrial processing with minerals/metals at elevated temperature (e.g. smelters, furnaces, refineries, coke ovens).
Release to the environment of this substance can occur from industrial use: formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines), electrical batteries and accumulators and vehicles. This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery), leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys) and rubber (e.g. tyres, shoes, toys).
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
ECHA has no public registered data on the types of manufacture using this substance.
This substance is used in the following activities or processes at workplace: transfer of chemicals.
Release to the environment of this substance can occur from industrial use: formulation of mixtures. Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
This substance is used in the following activities or processes at workplace: transfer of chemicals.
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
ECHA has no public registered data indicating whether or in which chemical products the substance might be used.
This substance is used in the following areas: mining. This substance is used for the manufacture of: chemicals.
This substance is used in the following activities or processes at workplace: transfer of chemicals.
Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites.
This substance is used in the following activities or processes at workplace: transfer of chemicals.
ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
Precautions for using this substance have been recommended by its registrants under REACH, as follows:
General statements
Keep out of reach of children.
Prevention statements
When handling this substance: avoid breathing the dust, fume, gas, mist, vapours or spray; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.
Response statements
In case of incident: If in eyes: follow instructions specified by manufacturer/supplier. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a poison center or doctor/physician. If on skin: wash with soap and water.
Disposal statements
The substance must be disposed in accordance with local/regional/national/international regulation.
Guidance on the safe use of the substance provided by manufacturers and importers of this substance.
Registrants/suppliers
This section provides information on suppliers, importers or manufacturers of a substance (active and inactive) that have to register their substance under REACH.
Registration status | |
---|---|
Status in REACH-IT | Displayed in Brief Profile |
Active | Always as Active |
Cease manufacture | Always as Inactive |
Revoked registrations | Active/Inactive (pending). Due to ongoing appeals, all registrations flagged as revoked are published as Active pending the appeal outcome. When the appeal outcome is known, the registration will appear as Inactive |
Annulled registrations | In the case of a merge between two companies having a registration for the same substance, the higher tonnage band registration is maintained as active, and the other registration is annulled. The annulled registration is still legally valid and considered as an active registration, because the registration number could be present on safety fata sheets and may already be communicated throughout the supply chain. |
Under specific conditions, a registrant can claim confidentiality of their identity. If there is a confidentiality claim, an indication is provided with the tag [Confidential].
- " VASMAK 2014 " LTD, "Spartak",№19, entrance-B 2800 Sandanski Bulgaria
- "Kolio" EOOD, "Aleko Konstantinov" 6 2700 Blagoevgrad Blagoevgrad Bulgaria
- "Policvet" OOD, Iosaf Bdinski 70 vh.B 3700 Vidin Bulgaria
- "VASILEVI 04" Ltd., 23 Sheinovo Str. 5980 Cherven Bryag district Pleven Bulgaria
- A. & D. Kallimanis & SIA O.E., Pytiousis 10 34100 Nea Lampsakos Chalkidas Greece
- A. Tokis k SIA O.E., Mpizani Ioanninon Tah. Thirida: 217 45500 Ioannina Nomos Ioanninon Greece
- A/S Ikast Betonvarefabrik, Lysholt Allé 4 7430 Ikast Denmark
- Acciaierie d'Italia S.p.A., Viale Certosa 239 20151 Milano Lombardia Italy
- Adriatica Legnami srl, SS 16 Km 855,5 72015 Fasano Brindisi Italy
- Afoi Binta O.E., 2xlm PEO Katerinis - Thessalonikis 60100 Katerini Greece
- Afoi D. Mantzana OE, 5o xlm E.O. Lamias - Karpenisiou 35100 Lamia Greece
- Afoi Dimitriou Sifouniou OE, Smalou Lerou 85400 Nisos Leros Greece
- AFOI EYAG. PRODROMITI O.E., 2nd klm Vonitsas - Lefkadas 30002 Vonitsa Greece
- Afoi Giannakopouloi O.E., Memi Kyparissias 24500 Memi Kyparissias Greece
- AFOI KATSIOPERI O.E., 2nd KL TYRNAVOS-ELASSONA 40100 TYRNAVOS Greece
- Afoi Laki O.E., Andr. Papandreou 60 57200 Liti Thessalonikis Greece
- Afoi Lignou & SIA EE, Karterados Tax. Thirida 110 84700 Karterados Thira Greece
- Afoi M. Mpotsiou & SIA OE, VI.PE. IOANNINON Rodotopi 45500 IOANNINA Greece
- AFOI N. VAVAROUTA O.E., RIOLOS 25200 ACHAIA KATO ACHAIA Greece
- AFOI NTELEKOU O.E., AKTI PSACHNON 34400 DIMOS DIRFION - MESSAPION EYBOIA Greece
- Afoi P. Krampoviti OE, Themidos 27 18233 Ag. I. Rentis Attiki Greece
- Afoi Paraskeva EE, Mariolata Gravias 33057 Nomos Fokidas Greece
- Afoi Pavlou Foti O.E., Ano Agioi Anargyroi 47100 Arta Greece
- Afton Chemical S.R.L. (Woluwe), Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium
- AGRODOMIKI LTD, KAMPOS GAVRIOY 84501 NISOS ANDROS NOMOS KYKLADON Greece
- Air Liquide Austria GmbH, Sendnergasse 30 A-2320 Schwechat Austria
- Air Liquide Danmark A/S, Industriparken 31 2750 Ballerup Denmark
- Air Liquide Deutschland GmbH, Luise-Rainer-Straße 5 D-40235 Düsseldorf Germany
- AIR LIQUIDE FRANCE INDUSTRIE, EL- AMC-EMC Chalon Archibald Scandocs Center / 0715 - CS 80010 81700 BLAN France
- AIR LIQUIDE HELLAS AEBA, thessi Stefani GR-193 00 ASPROPYRGOS ATTIKI Greece
- AIR LIQUIDE ITALIA SERVICE S.r.l., Via Calabria 31 20158 Milano MI Italy
- Air Liquide Romania SRL, 11, Dinu Vintila 021101 Bucharest Bucharest Romania
- AIR PRODUCTS S.A.S., 78 Rue Championnet 75881 Paris cedex 18 France
- Air Products Sp. z o.o., Komitetu Obrony Robotników 48 02-146 Warszawa Poland
- AL Air Liquide España S.A., Paseo de la Castellana 79 28046 Madrid Spain
- ALBEMARLE CATALYSTS COMPANY B.V., Nieuwendammerkade 1-3 PO Box 37650 1030 BE Amsterdam Netherlands
- Alexopoulos Andreas, G. Kontopoulou 73 25100 Aigio Greece
- Andaluza de Cales, S:A:, Ctra Morón Montellano Km3 ES 41530 Morón de La Frontera Sevilla Spain
- ANTOANETA HB Ltd., 4A Akazia str. 2030 Kostenets district Sofia Bulgaria
- ANTONINO ANCIONE S.p.A., C.DA TABUNA 97100 RAGUSA SICILY Italy
- Aptourahman Gioulsoum, Thesi Lefkomilos 69100 Folia Komotinis Nomos Rodopis Greece
- Arampatzi Antonia, Nea Kerdylia 62041 Amfipoli Nomos Serron Greece
- ARES 08 Ltd., 4 Nikola Vaptsarov str. 4150 Rakovski district Plovdiv Bulgaria
- ARGOCEMENT EPE, Tavrou 21 & Themidos 33 18233 Ag. I. Rentis Attiki Greece
- Arrow Regulatory (Ireland) Ltd OR1904, Suite 303 9 Pembroke Street Upper D02 KR83 Dublin 2 Ireland
- Aschaffenburger Versorgungs-GmbH, Werkstraße 2 63739 Aschaffenburg Bayern Germany
- Asvestopoiia Evrou A.E., 1o xlm Alexandroupolis - Avantos 68100 Alexandroupoli Nomos Evrou Greece
- Asvestopoiia Kritis A.E., Fones Apokoronou Dimos Krioneridas 73007 Chania Nomos Chanion Greece
- Athanasios Devetzoglou & SIA E.E., Trapezountos 30 18453 Nikaia Greece
- AVANTOR PERFORMANCE MATERIALS POLAND SPÓŁKA AKCYJNA, Sowińskiego 11 44-101 Gliwice Silesia Poland
- AVN Ltd., Industrialna 1 6000 Stara Zagora Bulgaria
- AWG Abfallwirtschaftsgesellschaft mbH Wuppertal, Korzert 15 42349 Wuppertal NRW Germany
- Baerlocher GmbH, Freisinger Str. 1 85716 Unterschleissheim Germany
- BALOGH-MÉSZ Ker. Bt., Rákóczi út 59/A 6090 Kunszentmiklós Hungary
- basi Schöberl GmbH & Co. KG, Im Steingerüst 57 76437 Rastatt Germany
- Baumit GmbH, Wopfing 156 2754 Waldegg Austria
- Bayer AG, Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany
- Bergbau Goslar GmbH, Bergtal 18 D-38640 Goslar Germany
- Bidzho95, Екзарх Йосиф 25 2870 Марикостиново Petrich Bulgaria
- BIKSTON-Georgiev EOOD, 12 Nikola Vaptsarov str. 4490 Septemvri district Pazardzhik Bulgaria
- BIZIOS & SIA O.B.E.E., BIOMIXANIKI PERIOXI KASTORIAS T.TH. 62 55200 ARGOS ORESTIKO Greece
- BKS-Elhovo Ltd., 5 Slavianska str. 8700 Elhovo district Yambol Bulgaria
- BLAGOUSTROISTVENI STROEJI EOOD, 18 Bratia Miladinovi str. 18 Bratia Miladinovi str. 8800 Sliven Bulgaria Bulgaria
- BLRT Grupp AS, Kopli 103 11712 Tallinn Estonia
- BOC Gases Ireland Ltd, John F Kennedy Drive Bluebell D12 PP63 Dublin Ireland
- Bodnár István EV, Szent Imre út 113. 2335 Taksony Hungary
- Borbás János, Templom u. 22. 5744 Kevermes Hungary
- Bornholm Mørtel og Transport ApS, Skolekrogen 6 3740 Svaneke Denmark
- Borregaard AS as Only Representative, P.O. Box 162 1701 Sarpsborg Norway
- Bouga Brs O.E., Klada 23100 Sparta Greece
- Brunschwig Chemie BV, hexaanweg 2 1041 AX Amsterdam Netherlands
- BUILDINGGROUP-SK EOOD, 45 Georgi Dimitrov str. 3750 Dimovo District Vidin Bulgaria
- Burgo Ardennes, rue de la papeterie, 1 6760 Virton Belgium
- C.S.B. GmbH, Dujardinstr. 5 47829 Krefeld Nordrhein-Westfalen Germany
- CAL DE CASTILLA, S. A., Carretera de Valencia, km. 31 28500 Arganda del Rey Madrid Spain
- Cal Industrial SL, Av. Pio XII 22 Oficina n°2 31008 Pamplona Spain
- CAL.ME. S.P.A., Z. I. Marcellinara SS280km 16,7 88040 MARCELLINARA (CZ) Calabria Italy
- CALCE BARATTONI SPA, VIA LAGO DI ALLEGHE 45 36015 SCHIO VICENZA Italy
- calci-chaux, 39 rue des jacquets- le puy vacher 03450 ebreuil France
- Calcidrata - Indústrias de Cal, S. A., Estrada 5 de Outubro, Pé da Pedreira 2025-161 Alcanede Portugal
- calcidrata s.p.a., valsugana, 6 09123 Cagliari Sardegna Italy
- Calcis Lienen GmbH & Co. KG Werk Brochterbeck, Am Kalkwerk 1 49545 Tecklenburg Germany
- Calcis Warstein GmbH & Co. KG, Rangetriftweg 108 59581 Warstein NRW Germany
- CALCISERNIA S.P.A., Via Giovanni Berta 199 86170 Isernia Molise Italy
- CALCIT J.S.C., Industrial zone "North" 4230 Asenovgrad Plovdiv Bulgaria
- Calcit-LTD, 3 Paisy Hilendarski Str. 2200 Slivnitsa Sofia Bulgaria
- calera de alzo s.l., egileor auzoa, 101 20268 altzo guipuzcoa Spain
- Caleras de San Cucao, S.A., Agüera-San Cucao (LLanera) 33425 España Spain
- Cales de la plana S.A., Pda Pedrera s/n 12592 Chilches Castellon Spain
- Cales de Llierca S.A., Afores, s/n 17853 Argelaguer Girona Spain
- CALES DE PACHS, S.A, Muntanya st. jaume s/n 08796 Pacs del Penedès Barcelona Spain
- CALES PASCUAL S.L., Cura Bau 15 46112 Masarrochos Valencia Spain
- Calgov, Cta Fuente Siantiago km2.5 41560 Estepa Spain
- Calmit GmbH, Linzer Straße 8 4820 Bad Ischl Upper Austria Austria
- Calmit Hungária Mészművek Kft., Rákóczi út 60. 2541 Lábatlan Hungary
- Calmit spol. s r. o., Gastanova 15 SK-81104 Bratislava Slovakia
- Cambridge Environmental Assessments part of RSK ADAS Europe (Ireland) Ltd (MP), Office Suite B, BlueBell Business Centre Old Naas Road D12XV7K Dublin Ireland
- CaO Hellas Makedoniki Asvestopoiia A.B.E.E, 6th Km Thessaloniki-Langada Rd 570 13 Thessaloniki Greece
- CaO Hellas Thessaliki Asvestopoiia A.B.E.E, 6th Km Thessaloniki-Langada Rd 57013 Thessaloniki Greece
- Carmeuse Chaux, 215 route d'Arras 62320 Bois Bernard France
- Carmeuse Czech Republic s.r.o, Mokra 359 664 04 Mokra Czech Republic
- Carmeuse Holding SRL, Str Carierei, 127A 500047 BRASOV Romania
- Carmeuse Hungaria Kft, HRSZ 064/1 7827 BEREMEND Hungary
- Carmeuse Nederland BV, 32-34 Nijverheidstraat 2802 AL Gouda Netherlands
- Carmeuse SA, rue des Deux Eglises 26 bte 2 1000 Brussels Belgium
- Carmeuse SA OR 1, rue du Château, 13A B-5300 Seilles Belgium
- Carmeuse Slovakia, Slavec, 179 049 11 Slavec Slovakia
- Carmeuse WEU O.R., Rue du Château 13a 5300 Seilles Belgium
- CARRIERES ET FOURS A CHAUX DUMONT-WAUTIER, Rue Charles Dubois, 28, 1342 Ottignies-Louvain-la-Neuve Belgium
- Carrières & Chaux Balthazard & Cotte, Rue du Pra Paris BP 6 38360 Sassenage France
- Carrières et fours a chaux de Dugny, BP 1 55100 Dugny sur Meuse France
- Carrières et Fours à Chaux Dumont-Wautier, Rue Charles Dubois, 28 1342 Ottignies-Louvain-la-Neuve Belgium
- CCD (Germany) GmbH, Berliner Allee 55 40212 Düsseldorf Germany
- CELCO S.A., Industriala 5 - 900147 Constanta Constanta Romania
- Celulosas de Asturias, S.A., Armental s/n 33710 Navia Asturias Spain
- Cementos Tudela Veguín S.A., Argüelles 25 33003 Oviedo Asturias Spain
- Ch. Traikos, Amfipoli Serron 62041 Amfipoli Serron Greece
- Charalampos Arvanitis k SIA O.E., Thesi Fousiazani 34100 Glyfa Chalkidas Greece
- CHAUX D'AUGMONTEL, Lieu-dit LA MOURETIE 81440 LAUTREC France
- Chaux de Boran, RD 603 60460 Précy sur Oise France
- Chaux de Bretagne, BP0124 53601 Evron France
- Chaux de la Tour, 1 chemin des Chaux de la Tour 13820 Ensuès La Redonne France
- CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
- CHEMIKA Marek Gajewski, Zebrzydowicka 117C 44-200 Rybnik Poland
- Cheminova A/S, Thyborønvej 78 DK-7673 Harboøre Denmark
- Chemische Fabrik Budenheim KG, Rheinstrasse 27 55257 Budenheim RLP Germany
- Chevron Oronite SA - OR - CVX Japan Ltd, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
- Chevron Oronite SA - OR - CVX Oronite Cy LLC, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
- Chevron Oronite SA M/I, Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France
- Chevron Phillips Chemicals International NV, Airport Plaza, Stockholm Building, Da Vincilaan 19 B-1831 DIEGEM Belgium
- Chimcomplex S.A. Borzesti, 3, Industriilor Street 601124 Onesti Bacau Romania
- Chirpanstroy Ltd., 2 Georgi Danchov str. 6200 Chirpan district Stara Zagora Bulgaria
- Christos M. Ilias k SIA O.E., Doliana 44004 Ioannina Greece
- Christos Ntafloukas & Yioi O.E., Leoforos Dimokratias 0 35100 Lamia Greece
- Christos Pantelaios k SIA O.E., Prodromos 84400 Paros Greece
- CHS Epi, a.s., Revoluční 1930/6 40032 Ústí nad Labem Czech Republic
- CIECH Soda Polska S.A., Fabryczna 4 88-101 Inowroclaw Województwo Kujawsko-Pomorskie Poland
- Clariant Produkte (Deutschland) GmbH, August-Laubenheimer-Straße 1 Global Product Stewardship 65929 Frankfurt am Main Germany
- Clogrennane Lime Ltd, Clogrennane R93 EV26 Carlow Carlow Ireland
- COATEX SAS, 35 rue AMPERE 69730 GENAY France
- Comercial e Industrial ARIES S.A., PARAJE MONSARRO S/N 50137 PUEBLA DE ALBORTÓN ZARAGOZA Spain
- COMPRESSIONE GAS TECNICI S. cons. A r.l., Via Milano 4 - frazione Pobbiano 20090 Rodano (MI) Italy
- Corsaro Sebastiano s.r.l., via Nino Martoglio, n. 22 95040 Motta Sant'Anastasia - Catania Sicily Italy
- CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Canada Co.\Cie, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
- Csere Építőanyag Kereskedelmi és Szolgáltató Kft., Irmapusztai út 1. 8638 Balatonlelle Hungary
- Csige Ferenc Egyéni Vállalkozó, Nefelejcs u. 3 2921 Komárom Hungary
- Dallas Christos, Kastraki 51100 Grevena Greece
- Dan-grit A/S, Industrivej 14 6840 Oksbøl Denmark
- dankalk K/S, Aggersundvej 50 9670 Løgstør Denmark
- Daoultsoglou Georg. Kyriaki, Terma Gallikou 57008 Ionia Thessaloniki Greece
- Datsiadis Filippos EE, 10o xlm Kastorias Amintaiou 52056 Mavrochori Kastoria Greece
- Decsa, C/ Diseminado s/n - pont major 17007 Gerona Spain
- Degrémont Services, 116, rue des Houtraits 92508 RUEIL-MALMAISON France
- DELIOPOULOI EPE, 1st km Alexandria-Katerini Rd 59300 Alexandria Greece
- DETIVA LTD, gk."Alen mak", bl.8,vh.B,et.6,ap.15 2700 Blagoevgrad Bulgaria
- DEÁK JÓZSEF Vállalkozó, Szabadság u. 10. 8697 Öreglak Hungary
- DHM SARANTOU YIOI SAMOXYL AVEE, Petrionas Kontakaiika 83200 Karlovasi Samou Greece
- DIMI METAL Ltd., 46 Petko Slaveykov str. 5980 Cherven bryag district Pleven Bulgaria
- Dimitrios Karmazis & Sia OE, 3 km National Road Kozanis - Larissas 50100 Kozani Greece
- Dion. Kon. Mantas, 2o xlm. EO Pyrgou - Patron 27100 Pyrgos Ileias Greece
- Domika Pasisis S.A., Palaiopanagia Nafpaktou 30300 Nafpaktos Greece
- Domika Ylika Kataskevastiki EPE, Lofiskoi Aulonariou 43009 Lofiskoi Aulonariou Euvoia Greece
- Domiki P. Pavlides S.A., 5o xlm Giannitson - Thes/nikis (Tax. Thirida: 9) 58100 Giannitsa Greece
- Drosos Ap. Stylianos, Euinochori 30014 Mesologgi Greece
- Dräger Safety AG & Co. KGaA, Revalstr. 1 23560 Lübeck Germany
- Dullinger Kalk GmbH, Peilsteinstrasse 21 5323 Ebenau Salzburg Austria
- EFTHIMIOU – SIFOUNIOU BROS & CO, Temenia 85400 Limenas Lakki Leros Dodekanisa Greece
- Entsorgungsgesellschaft Krefeld GmbH u. Co.KG, Parkstraße 234 47829 Krefeld Germany
- ET "Bedrok-Ivan Ivanov", 22A Raina Knyagina str. 8673 village Kukorevo,municipality Tundja district Yambol Bulgaria
- ET "BUKI-57 ANGEL MANDJUKOV", 30 Peyo Yavorov str. 2042 village Kostenets, district Sofia Bulgaria Bulgaria
- ET "Ljubomir Haygarov-LD", Petko Enev 100 8900 Nova Zagora Bulgaria
- ET ''Boris Pechev'', 3 Kliment Ohridski str. 5800 Pleven Pleven Bulgaria
- ET Andreev- Nikolay Andonov, 30 Tsar Samuil str. 30 Tsar Samuil str. 6450 Harmanli Bulgaria Bulgaria
- ET Botushev - Stefko Botushev, 33a, Vladislav Ochkov str. 8800 Sliven Sliven Bulgaria
- ET Iotka Ganova Madi 91, 36 Vasil Aprilov str. 36 Vasil Aprilov str. 5980 Cherven Briag Bulgaria Bulgaria
- ET Katerina-Geogri Evdenov, 62, Otec Paisii 3650 Valchedram district Montana Bulgaria
- ET KUSIGIN-ASEN ATANASOV, 18 Malchika str. 5731 Village Galata, district Lovech Bulgaria Bulgaria
- ET NIK-Nikolina Vasileva, 105 Repyblika str. 105 Repyblika str. 3540 Varshets Bulgaria Bulgaria
- ET SOTIR SOTIROV, j.k.G.Benkovski,bl.8,fl.3,ap.162 8600 Yambol Bulgaria Bulgaria
- ET Todor Petkov-TIP 24, Panayot Volov 70A 5980 Cherven bryag Pleven Bulgaria
- ET Yankovi Yanko Hristov, 9 Slavei str. 6151 village Gorno Sahrane Municipality Pavel Banya, District Stara Zagora Bulgaria
- Eurogas S.r.l., via Pradazzo, 22 26012 Castelleone Cremona Italy
- Eurogaz - Gdynia Sp. z o.o., Czechoslowacka 3 81-963 Gdynia pomorskie Poland
- EUROPEENNE DES CHAUX ET LIANTS (ECL), 2745 route du Bugey Hameau de Flosailles 38300 SAINT SAVIN France
- ExxonMobil Petroleum & Chemical BV, Polderdijkweg 2030 Antwerpen Belgium
- FARKAS MÁTYÁSNÉ TÜZELŐSZER ÉS ÉPÍTŐANYAG KERESKEDŐ MÉSZ OLTÓ, Nádor u. 13. 8230 Balatonfüred Hungary
- FASSA SRL, VIA LAZZARIS 3 31027 SPRESIANO TV Italy
- FAVORIT-3003 LTD, 33 "Treti mart" str. 8700 Elhovo district Yambol Bulgaria
- Faxe Kalk A/S, Hovedgaden 13 4654 Faxe Ladeplads Denmark
- Fels-Werke GmbH, Geheimrat-Ebert-Straße 12 38640 Goslar Germany
- Flouras Lampros, Leoforos Enoseos 8 82132 Chios Chios Greece
- FormiChem GmbH, Anna-von-Philipp-Strasse B33 86633 Neuburg a.d. Donau Germany
- Fornace Sberna srl, via strada colli nord,12 46049 volta mantovana mantova Italy
- FORNACI CALCE GRIGOLIN spa, via Bombardieri, 14 31010 Ponte della Priula TV Italy
- Fornaci da Calce Berini Edgardo & C. sas, Via del Municipio, 43 33010 Reana del Rojale Italy
- FORTISCHEM a.s., M.R.Stefanika 1 972 71 Novaky Slovakia
- FORUM 22-MARONOV EOOD, 11 "Rodopska" str. 11 "Rodopska" str. 4230 Assenovgrad Bulgaria Bulgaria
- Fotopoulos Georgios, 5th klm National Road Pirgos - Kiparissia 25058 Epitalio Ileia Greece
- FP-Pigments GmbH, Am Haupttor 06237 Leuna Germany
- FP-Pigments Oy, Ahventie 4 A 21-22 02170 Espoo Finland
- Fradical, Fábrica de transformação de cal, Lda, Rua Corpo de Deus nº126 4ºAndar 3000-121 Coimbra Portugal
- FRAGKOS AEVE, Varela Vatheos Samou 83100 Samos Greece
- Frejlev Cementstøberi A/S, Nibevej 331/151 Frejlev 9200 Aalborg SV Denmark
- G. & E. Altanis OE, Thesi Valtos 33200 Itea Fokida Greece
- G. Aggelinoudis - N. Menexes, 14o xlm. Thes/nikis - Chortiati 57010 Asvestoxori - Thessalonikis Greece
- Garantproektstroy OOD, 23 Jivovci str. 3500 Berkovitza district Montana Bulgaria
- GBK GmbH Global Regulatory Compliance, Königsberger Straße 29 55218 Ingelheim Germany
- GEA Group Aktiengesellschaft, Peter-Müller-Str. 12 40468 Düsseldorf Germany
- Georesurs EOOD, Stara Planina 20 2730 Simitly Blagoevgrad Bulgaria
- GG-CERT e.V. - zertifizierte Produkte - zertifizierte Prozesse -, Annastr. 67-71 50968 Koeln Germany
- Giatsios Ioannis, Terma Thoma Lada 51100 Grevena Greece
- Giotas Georgios & SIA OE, Anonimou 2 & Protagora Gonia 69100 Komotini Greece
- GIRK Kalun d.d., Stjepana Radica 5 22320 Drnis Dalmatia Croatia
- GKW-Gemeinschaftsklärwerk Bitterfeld-Wolfen GmbH, Salegaster Chaussee 2 OT Greppin 06804 Bitterfeld-Wolfen Germany
- Global Product Compliance (Europe) AB, IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden
- Grupo Empresarial ENCE, Paseo de la castellana, 35 1ª Planta 28046 MADRID MADRID Spain
- GSV Kereskedelmi Kft., Vámospércsi u. 37 4034 Debrecen Hungary
- Gál Dénes Egyéni vállalkozó, Országút u. 1000-1001 2471 Baracska Hungary
- Gál Sándor EV, Dolgozók u 5 4492 Dombrád Hungary
- HAJ-ANT BT, Kossuth L. u. 107. 7700 Mohács Hungary
- Halliburton Manufacturing and Services Ltd., Columbusstraat 19 7825 VP Emmen Netherlands
- Hallstar Italia Srl con socio unico , Piazza Meda, 3 20121 Milano Lombardia Italy
- Hans G. Hauri KG Mineralstoffwerke, Bergstraße 114 79268 Bötzingen Germany
- HARDWORKER GYÁRTÓ ÉS SZOLGÁLTATÓ KFT., Debreceni u. 39. 4126 Kismarja Hungary
- HASIT Šumavské vápenice a omítkárny, s.r.o., Velké Hydčice 34101 Velké Hydčice Czech Republic
- Hastenrather Kalkwerke Wwe. W. Meyer GmbH& Co. KG, Alberstr. 57a 52249 Eschweiler Germany
- Hastrup Mørtel- & Singelsværk ApS, Ådalsvej 6 4720 Præstø Denmark
- HCM 1890 Hejőcsabai Cement- és Mészipari Zrt., Fogarasi utca 6. 3508 Miskolc Hungary
- HeidelbergCement AG, Berliner Straße 6 69120 Heidelberg Germany
- HELLENIC MINING PUBLIC CO LTD, Kyriakos Matsis Avenue 1a, P.O.Box 21510 1510 Nicosia Cyprus
- Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
- Herborg mørtelværk, Møllevej 24 6920 Herborg - Videbæk Danmark Denmark
- Hermann Trollius GmbH, Am Haeselberg 1 92283 Lauterhofen Bayern Germany
- Holzkalkbrennerei Robert Koerndl, Riedenburger Str. 12 93336 Altmannstein Bayern Germany
- HORAFAS A. KAI SIA OE, Lygias Nafpaktou 30300 Nafpaktos Greece
- Horváth János egyéni vállalkozó, Rákóczi u. 175. 7543 Beleg Hungary
- Horváth Tüzép Építőipari és Kerskedelmi Kft., Ilki út 1. 4800 Vásárosnamény Hungary
- HTV Építőipari és Kereskedelmi Kft., Buda út 22. 9023 Győr Hungary
- Hundisburger Baustoffmanufaktur, Inh. Foerderverein Technisches Denkmal Ziegelei Hundisburg e.V., Jacob-Bührer-Str.2 OT Hundisburg 39343 Haldensleben Sachsen-Anhalt Germany
- I. Chatzinikolaou & Yioi AE, Merarxias Serron 19 69100 Komotini Greece
- I. SPARAKIS - A. STROYMPOYTAS O.E., Kato Alissos 25002 Kato Achaia Greece
- IAK d.o.o. , Kresnice 14 1281 Kresnice Slovenia
- IDARA TRADE EOOD, 45 Bulgaria Blvd. entr. A, fl.2,ap.7 6450 Harmanli district Haskovo Bulgaria
- Imerys Mineral AB, Tunadals Hamnen Box 711 85121 Sundsvall Sweden
- IMERYS PCC FRANCE, Route d'Arles Salin de Giraud 13129 Arles France France
- INDUSTRIA CALCE CASERTANA SRL, ZONA INDUSTRIALE ASI 84021 Buccino Salerno Italy
- INEOS Manufacturing Deutschland GmbH, Alte Strasse 201 50769 Koeln Germany
- Inkom PV OOD, Georg Papazov 9/3 8600 Yambol Bulgaria
- INTERBAU Ltd., terrain Koleva livada 1 5300 Gabrovo Bulgaria Bulgaria
- InterCal Slovenija, proizvodnja apna in apnenca d.o.o., Savska cesta 1 1410 Zagorje ob Savi Slovenia
- Intracoat B.V., Klef 6 5763 PG Milheeze Netherlands
- Ioannis Makrogiannis, Chora Samou 83103 Samos Greece
- Irish Oxygen Company Limited, Waterfall Road 021 Cork Ireland
- Ismail Metin, 1o xlm Komotinis Karidias 69100 Komotini Greece
- Italcalce, Via Salissano 1 04019 Terracina Italy
- IZOLBET Spółka z ograniczoną odpowiedzialnością, ul. Kowalska 9 09-500 Gostynin Poland
- J. Bergmann GmbH & Co., Azendorf 63 95359 Kasendorf Germany
- JANAKIEV 09 , Ul. HRISTO BOTEV, № 37 4600 VELINGRAD Bulgaria Bulgaria
- Johnson Matthey Chemicals GmbH (OR), Wardstraße 17 46446 Emmerich am Rhein Germany
- K-GY-64 Kft., Kossuth u. 21. 7541 Kutas Hungary
- K. - A. Chatziathanasiou, N. Lampsakos Chalkidas 34100 N. Lampsakos Chalkidas Greece
- K. Monastirlis - AN. Georgiadou OE, Nea Kallikrateia 63080 Nea Kallikrateia Xalkidiki Greece
- K. Raikos & SIA Asvestopoiia Renti O.E., Tavrou 31 17778 Tavros Nomos Attikis Greece
- K. Raikos A.E., Thesi Tzaverdella 19300 Aspropyrgos Nomos Attikis Greece
- Kabel Premium Pulp & Paper GmbH, Schwerter Strasse 263 58099 Hagen Germany
- Kalcinator KFT, Fogarasi str. 6 3501 Miskolc Miskolc Hungary
- Kalcitker-Transz Kft., Kazinczy Ferenc ter 7. fsz. 2 3700 Kazincbarcika Hungary
- Kalk A/S, Bredeløkkevej 12 4660 Store Heddinge Denmark
- Kalkwerke H.Oetelshofen GmbH & Co. KG, Hahnenfurth 5 42327 Wuppertal Nordrhein-Westfalen Germany
- Kalkwerke Otto Breckweg GmbH & Co.KG, Neuenkirchener Straße 400 48432 Rheine Germany
- Karagianni A.E., El. Venizelou 69 85300 Kos Greece
- Karászi Lászlóné, Kossuth út 222. 4523 Pátroha Hungary
- Katsonis Antonis, Afroksilia 30300 Nafpaktos Greece
- KER-EX '94 KFT., Attila u. 2. 6422 Tompa Hungary
- KIS - SABEV DENCHEV SIE , 116 ANGEL KANCHEV str. 116 ANGEL KANCHEV str. 5350 TRYAVNA Bulgaria Bulgaria
- klironomoi kalaitzi patras koinonia, 4th km mytilinis-kallonis panagioti vostani 10a 81100 mytilini mytilini Greece
- Knauf Marmorit GmbH, Ellighofen 6 79283 Bollschweil Germany
- Knauf SIA, Daugavasstrasse 4 2118 Riga Gemeinde Stopini, Bezirk Riga Latvia
- Knoell NL-OR-S07, Agro Business Park 75 6708 PV Wageningen Netherlands
- Kokliotis Vasileios, Asklipiou 8 18900 Salamina Greece
- KON/NOS EMMANOUILIDIS & SIA O.E., 2nd km KSANTHIS - KAVALAS 67100 KSANTHI Greece
- Koninklijke Coöperatie Cosun U.A., Van de Reijtstraat 15 PO Box 3411 4800 MG Breda Netherlands
- KONSTANTINOS KARANIKOLAS & SIA O.E., MANAS 75 30200 MESOLOGGI Greece
- Korodimos Christos & SIA OEBE, Delfon 100 32004 Arachova Greece
- Kouravanas Dimitrios & SIA OBEE, Imvrou & Aidiniou Nea Magnisia 35100 Lamia Greece
- Kourtidis Ioannis, 1o xlm Ptolemaidas - Kozanis 50200 Ptolemaida Greece
- Kovács László András Egyéni Vállakozó, Ady E. út 17. 2870 Kisbér Hungary
- Kreber Kereskedelmi KFT, Ezerjó u. 43. 1165 Budapest Hungary
- Krinos S.A. - Hydrated Lime, Pireos 84A 18346 Moshato Nomos Attikis Greece
- Kritharis S.A., 20th km N.E.O. Athens - Korinthos 19200 Eleysina Greece
- Krkonosske Vapenky Kuncice, akciova spolecnost, Kunčice nad Labem, č.p.150 543 71 Kunčice nad Labem Czech Republic
- Kubicsek János EV, Gábor Áron u. 16. 6328 Dunapataj Hungary
- Kurt & Carlo Kristensen A/S, Klejtrupvej 9B 9500 Hobro Denmark
- KUTASI TÜZÉP KFT., III. Ker. 32. 6235 Bócsa Hungary
- Kyknos S.A. Asvestopoiia Poltopoiia, Perioxi Gka 10th km EO Korinthos-Argos 20005 Athikia Nomos Korinthias Greece
- L'OREAL, 14 rue Royale 75008 Paris France
- La Nuova Fornaciaia srl, C.da Incarrozza SP12 95045 MISTERBIANCO CATANIA Italy
- LATERLITE S.p.A., Via Vittorio Veneto 30 43045 Rubbiano di Solignano PR Italy
- Lausitzer und Mitteldeutsche Bergbau-Verwaltungsgesellschaft mbH - Bereich Kali-Spat-Erz, Am Petersenschacht 9 99706 Sondershausen Germany
- LAZARINA 80 Ltd., village Chakalzi municipality Dzhebel 6850 Kardzhali Bulgaria Bulgaria
- LB Cemix, s.r.o., Tovární 36 37312 Borovany Czech Republic
- Leona La Ferla spa, contrada petraro 96010 Melilli Italy
- Leube Zement GmbH, Gartenauerplatz 9 5083 St. Leonhard Salzburg Austria
- Lezis Basileios, Lappa 27052 Kato Achaia Greece
- Lhoist Bukowa Sp. z o.o., ul. Osiedlowa 10 Bukowa 29-105 Krasocin Poland
- Lhoist France Ouest, 15 rue Henri Dagalier 38000 Grenoble France
- LHOIST INDUSTRIES (JEMELLE), Rue Charles Dubois, 28 1342 Ottignies-Louvain-la-Neuve Belgium
- Linde Gas A.S., U Technoplynu1324 198 00 Prague Czech Republic
- Linde Gas AB, Rättarvägen 3 16968 Solna Sweden
- Linde Gas GmbH, Waschenbergerstrasse 13 4651 Stadl-Paura Austria
- LINDE GAS HUNGARY CO.LTD., Carl von Linde 1. 9653 Répcelak Western Transdanubia Hungary
- Linde Gaz Polska Sp. z o.o., Al.. Jana Pawla II 41A 31-864 Krakow Poland
- Linde Gaz Romania SRL, Avram Imbroane 300136 Timisoara Timis Romania
- Linde GmbH Gases Division, Seitnerstrasse 70 DE-82049 Pullach Germany
- Linde Hellas Single Person Limited Liability Company, Thesi Trypio Lithari 19 600 Mandra Attica Greece
- LINDE PLIN d.o.o., Kalinovac 2/a HR-47000 Karlovac Croatia
- Linde Portugal Lda, Av. Infante D. Henrique Lote 21-24 Cabo Ruivo 1802-810 Lisboa Portugal
- LTE SRL, Via L.Lama 10 25033 Cologne - Brescia Lombardia Italy
- Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
- Lusical, Valverde 2025 Alcanede Portugal
- M. Lamprou - K. Ziogas - A. Pappas O.E., Thesi Loutsa Vounoplagia 45500 Ioannina Greece
- M.I. Stagakis SA, Atsipopoulou 74100 Rethimno Greece
- Magklaras Il. - Magklaras St. CO, Pedini (Thesi Parliaka) Tax. Thirida: 343 45500 Ioannina Greece
- MAKRIS NIKOS & SIA O.E., ARILLAS KABBADADON 49081 KERKYRA Greece
- MARINELLI A. CALCE INERTI SRL, Via Leonardo da Vinci, 9 06073 Perugia - Mantignana di Corciano Italy
- MECHO-TVT EOOD, 23 Saborna str. 23 Saborna str. 6450 Harmanli Bulgaria Bulgaria
- MEGATER LTD, 1 Industrialna str. 1 Industrialna str. 6000 Stara Zagora Bulgaria Bulgaria
- Menelaos Papathanasiou & SIA O.E., Zygos Kavalas 65500 Kavala Greece
- Merck KGaA, Frankfurter Strasse 250 64293 Darmstadt Germany
- Messer Austria GmbH, Industriestraße 5 2352 Gumpoldskirchen Austria
- Messer Energo Gaz S.R.L, Santierului nr. 1 RO-337532 Mintia - Deva Jud Hunedoara Romania
- Messer France S.A.S., 25 rue Auguste Blanche 92816 Puteaux Cedex France
- Messer Hungarogáz Kft, Váci út 117 1044 Budapest Hungary
- MI-PET Ltd., 27 Vasil Kanchov str. 3000 Vratsa Bulgaria Bulgaria
- MIBOKI Ltd, 1 Stremlenie str. 1 Stremlenie str. 7000 Ruse Bulgaria Bulgaria
- MICROLIME - Produtos de Cal e Derivados SA, Parque Empresarial da SNES 2840-104 Aldeia de Paio Pires Seixal Portugal
- Midtjydsk Mørtelfabrik Amba, Sandagervej 32 7400 Herning Jylland Denmark
- Milionis A.E., Ampelonas - Larisas 40400 Ampelonas - Larisas Greece
- minermix srl, C.da Matarano 3/a 72015 Fasano (BR) Italy
- Mitsubishi Gas Chemical Europe GmbH, Immermannstraße 13 40210 Düsseldorf Germany
- Moccia Industria spa, via benevento 167 82016 montesarchio Italy
- Momentive Performance Materials Specialties Srl, Zona Industriale- Località Rivolta Del Re Termoli 86039 Termoli CB Italy
- Mondi SCP, a.s., Ružomberok, Tatranská cesta 3 034 17 Ružomberok Slovakia
- Mondi Štětí, a.s., Litoměřická 272 41108 Štětí Czech Republic
- Monolit-21-Andonov i Zahov, Stanke Dimitrov 7 2800 Sandanski Bulgaria
- MONT-BAU-PTM Kft., Kossuth L. u. 56/A 6090 Kunszentmiklós Hungary
- MORANDI BORTOT SRL, via Piave, 70 31028 Vazzola Italy
- MOUEMIN MEHMET, ARCHI KONSTANTINOUPOLEOS 69200 X. IASMOS RODOPI Greece
- Mpegliti St. AFOI AVETE, Kiato, Thesi Arkouda 20200 Kiato Nomos Korinthias Greece
- Mpletsas Apostolos k SIA O.E., Parapotamos Igoumenitsas 46200 Parapotamos Igoumenitsas Nomos Thesprotias Greece
- Murer & Entreprenør Michael Martlev v/Mikael Martlev, Vollerupgade 32 4792 Askeby Denmark
- Märker Kalk GmbH, Oskar-Märker-Str. 24 86655 Harburg Germany
- MÉSZ-KÉCSKE Kft., Oláházi d. 8/a 6060 Tiszakécske Bács-Kiskun megye Hungary
- N. Siamis & CO Lime Factory Olympos, 5 km National Road Larisas - Thesalonikis 41336 Larisa Greece
- NIK -INDUSTRY EOOD, 11 Luben Karavelov str. 2440 Zemen district Pernik Bulgaria
- NIK-MIK-VIK Ltd., 5 Roza str. 5750 Yablanitsa district Lovech Bulgaria
- Nikitopoulos Euaggelos, 3o xlm Argous - N. Chiou 21200 Argos Greece
- Nikolaus Müller Kalkwerk-Natursteinwerke GmbH & Co. KG, Industriestraße 54579 Üxheim Ahütte Germany
- Nikos Diamantis & SIA OE, Panagiouda 81100 Mytilene Lesvos Greece
- NIPPON GASES ESPAÑA SL, C/Orense, 11 5º Planta 28020 Madrid Spain
- Nordenhamer Zinkhütte GmbH, Johannastr. 1 26954 Nordenham Germany
- Nordkalk AB, Kungsängsvägen 22 73129 Köping Sweden
- Nordkalk Oy Ab, Skräbbölevägen 18 21600 Parainen Finland
- NOUSIAS STAVROS & SIA OE, Nikis Avenue 47 58200 Edessa Greece
- Ntelalis Pantelis, Afisio 23100 Sparti Greece
- OGNYANOVO-K AD, 7, Pozitano Str. 1301 Sofia Sofia Bulgaria
- OIKODOMIKA KATSIKARIS AE, Merarhias Serron 55 1o xlm Komotinis – Ksanthis 69100 Komotini Greece
- Omya AB, Kalendegatan 18 211 35 Malmoe Sweden
- Omya GmbH Gummern, Gersheimstr 1-2 9722 Gummern Austria
- Omya Netherlands BV, Haven-Nr. M 312 Middenweg 47 4782 PM Moerdijk Netherlands
- Omya OY, Helsinki, Kasarmikatu 22 00130 Helsinki Finland
- OMYA S.A., Fãbrica - Apartado 86 2901-901 Setúbal Portugal
- Omya SAS, 6, rue Pierre Semard 51240 Omey France
- Only representative (No publishable name), null
- Oprenov-59 EOOD, ul. Veliko Tarnovo 2 2850 Petrich Bulgaria
- Orbán Profi Kft., Földvári u. 31. 6320 Solt Hungary
- Orsós István Egyéni Vállalkozó, Újtelep II u. 51. 8654 Ságvár Hungary
- Oxi-lower International sprl, Rue de bertransart 34 6280 Gerpinnes Belgium
- Oy Linde Gas Ab, Itsehallintokuja 6 02600 Espoo Finland
- Oy Woikoski Ab, PL 1 FI-52020 Woikoski Finland
- Panagiotis G. Spyridonos, 1o xlm Tithoreas-Leivadias 35015 Kato Tithorea Nomos Fthiotidas Greece
- Papaggelopoulos D. Emmanouil, Platanovrysi D. Farron 25008 Platanovrysi D. Farron Greece
- Papastergiou Stergios, 1st km Serron-Dramas 62100 Serres Greece
- Paraschou Bros. S.A., Palaioxori N. Kavalas 64001 Palaioxori Nomos Kavalas Greece
- PARVOSTROY-G EOOD, village Parvomay Municipality Petrich 2890 Blagoevgrad Bulgaria Bulgaria
- Patinioti Anastasia & Yios, Kremasti 85104 Rodos Greece
- PAUNOV 82 EOOD , 1 Georgi Rakovski str. 1 Georgi Rakovski str. 4400 Pazardjik Bulgaria Bulgaria
- Pavlovi EOOD, 26 Tzar Osvoboditel Blvd. 6450 Harmanli district Haskovo Bulgaria
- PCC Rokita SA, Sienkiewicza 4 56-120 Brzeg Dolny Poland
- PECHASHKI EOOD, Kniaz 15 Aleksandar Batenberg str. bl.26,entr.A,fl.1,ap.1 5980 Cherven bryag district Pleven Bulgaria
- Penetron Hellas S.A., 50 Thrakomakedonon Av. 13679 Acharnes Attiki Greece
- Penman Consulting bvba 02, Avenue des Arts 10 B-1210 Brussels Belgium
- Performance Specialty Products Asturias, S.L.U., Valle de Tamón-Nubledo 33469 Tamón - Carreño Asturias Spain
- Petko Petkov 0101 EOOD, 15 Gradinska str. 6062 village Starozagorski mineralni bani district Stara Zagora Bulgaria
- Petroulias Sotirios, Pyrgos Trifylias 24400 Gargalianoi N. Messinias Greece
- Piotrowice Sp. z o.o., Piotrowice 106 27-630 Zawichost Poland
- Pipilis Konstantinos, Korinthou 4 19200 Elefsina Nomos Attikis Greece
- Poinios Stavros, Polykarpi Aridaias 58400 Polykarpi Aridaias N. Pellas Greece
- Poli-Farbe Vegyipari Kft., III. ker. 2. 6235 Bócsa Hungary
- Precheza a.s. Přerov, Nábřeží Dr. E. Beneše 24 751 62 Přerov Czech Republic
- Prefabet - Warszawa S.A., Augustówka 22C 02-981 Warszawa Mazowieckie Poland
- Premier Periclase Ltd, Boyne Road none Drogheda Louth Ireland
- Prendi Francesko, 3o xlm E.O. Pyrgou-Kyparissias 27100 Pyrgos Hleias Greece
- Procter & Gamble Manufacturing GmbH, Sulzbacher Strasse 40 65824 Schwalbach am Taunus Germany
- Profibaustoffe Austria GmbH, Mistelbacher Strasse 70 - 80 2115 Ernstbrunn Austria
- PRÍMA TÜZÉP FEHÉR ISTVÁNNÉ, Damjanich u. 31. 5130 Jászapáti Hungary
- PYRINAS S.A, Sperhoggia 24100 Kalamata Greece
- Püspök Gyula Egyéni Vállalkozó, Fő út 13. 6060 Tiszakécske Hungary
- QUALICAL, UNIPESSOAL, LDA., Rua das Boiças Casal das Boiças, Apartado 19 2025-256 Alcanede Santarém Portugal
- Quarzolith Putz und Mörtelerzeugung Sattledt GmbH, Dorfstrasse 5 5101 Bergheim Austria
- QUIMICA BASICA, S.A., Poligono Industrial Can Estape 08755 Castellbisbal Cataluña Spain
- Raffinerie Tirlemontoise S.A., Aandorenstraat 1 3300 Tienen Belgium
- Rathosi Sotiroula tou Dionysiou, 20o xlm PEO Patron - Pyrgou 25200 K. Achaia Greece
- RE.CO.MA. S.R.L., Via Oslavia, 3 04100 Latina Italy
- REACH 2008 Ltd., j.k.Mladost-1,bl.32,entr.A, fl.5, ap.10 1784 Sofia Bulgaria Bulgaria
- REACH GLOBAL SERVICES S.A., Rond Point Schuman, 6 Box 5 B-1040 Brussels Belgium
- REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
- Regartis s.r.o., Rubeška 393/7 19000 Prague 9 Czech Republic
- RESINOPLAST S.A., Chemin de Saint-Leonard Cedex 2 51863 Reims France
- Rheinkalk GmbH, Am Kalkstein 1 42489 Wülfrath Germany
- RHI Magnesita GmbH, Kranichberggasse 6 1120 Vienna Austria
- Rishøj Mørtelværk, Askjærvej 3 7250 Hejnsvig Denmark
- Rodiaki Asvestopoiia Nikolaou Sp. Doukeri & SIA O.E., 5th klm Leof. Rodou Kalitheas 85100 Rodos Greece
- Roundtower Building Products Ltd, The Forge Innishannon T12 W72X Cork Cork Ireland
- Rozsályi Mész Kft., Fő út 1/b 2162 Őrbottyán Hungary
- Rusal Aughinish Alumina, Aughinish Island 0000 Askeaton County Limerick Ireland
- Rygol Baustoffwerk GmbH & Co. KG, Deuerlinger Str. 43 93351 Painten Bayern Germany
- S. Doukeri & SIA O.E., Terma Megalou Alexandrou 13341 Ano Liosia Nomos Attikis Greece
- S.E. de Carburos Metálicos, S.A., Av. de la Fama, 1 08940 Cornellà de Llobregat (Barcelona) Spain
- S.G.M.Naiden Mitkov Ltd., 3 Stadiona str. entr.B,fl.2,ap.19 3600 Lom district Montana Bulgaria
- SAINT-GOBAIN WEBER A/S, Randersvej 75 Hinge 8940 Randers Denmark
- Sapio Produzione Idrogeno Ossigeno S.r.l., via Silvio Pellico 48 20052 Monza Italy
- SARA 2006 EOOD, 58 Hristo Botev str. 58 Hristo Botev str. 3444 Village Gromshin, district Montana Bulgaria Bulgaria
- Sasol Germany GmbH, Anckelmannsplatz 1 D-20537 Hamburg Germany
- SC Prescon Group Development SRL, Carierei 151 500052 Brasov Romania
- SC Simcor Var SA, Sat Cristur, Soseaua Hunedoarei, Nr. 1-3, Birouri, cam.03 330003 Deva Western Region / Hunedoara county Romania
- SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
- Schaefer Kalk Finland Oy, Selluntie 1 c/o UPM-Kymmene/Paperitehdas FI-75700 Kuusankoski Finland
- Schaefer Kalk France S.A.R.L., Leman Paper Mills Rue des Vignes F-74500 Publier France
- SCHAEFER KALK GmbH & Co.KG, Louise-Seher-Str. 6 D-65582 Diez Rheinland-Pfalz Germany
- Schaefer Kalk Tschechien s.r.o., Olsany 18 CZ-78962 Olsany Czech Republic
- Schaefer Kalk Österreich GmbH, Ludwig-Lassl-Straße 15 A-6112 Wattens Austria
- Schretter & Cie GmbH & Co KG, Bahnhofstrasse 27 6682 Vils Tirol Austria
- Schweighardt István egyéni vállalkozó, Mária telep. 35. 8151 Szabadbattyán Hungary
- Sejlstrup Entreprenørforretning A/S, Risgårdsvej 64 Sejlstrup 9480 Løkken Denmark
- Serafeim E. Sfikas, 2o xlm Lamias - Frantzi 35100 Lamia Greece
- SFIRIDIS DIMITRIS SA, 1o xlm Karystou - Marmariou 34001 Karystos Eyvoia Greece
- SIA «BaltGips», Ķīļi-6 LV-2118 Salaspils Latvia
- SIAD Czech spol. s r.o., K Hájům 2606/2b 155 00 Praha 5 - Stodůlky Czech Republic
- Siegfried Krinke Vertriebs-GmbH, Achimer Landstraße 30 27321 Thedinghausen Deutschland Germany
- SIGMA-ALDRICH CHEMIE GMBH, Riedstrasse 2 89555 Steinheim Germany
- Sika Norge AS, Sanitetsveien 1 2013 Skjetten Norway
- Sipőcz Kft, 0126/129. 2142 Nagytarcsa Hungary
- Siropoulos Georgios, 1st km Eksaplatanou - Aridaias 58004 Eksaplatanos Greece
- Siska Lajos Józsefné Egyéni Vállalkozó, Újtelep u. 11. 9061 Vámosszabadi Hungary
- SKANDALIS S.A., PAROIKIA 84400 PAROS Greece
- Skovsted Mørtelværk, Oddershedevej 4 Skovsted 7700 Thisted Denmark
- SMA Mineral AB, Högbergsvägen 60 68240 Filipstad Sweden
- SMA Mineral Burgas Var Ltd, 120 Stefan Stambolov Blvd. 8000 Burgas Bulgaria
- SMA Mineral Oy, Selleenkatu 281 95450 Tornio Finland
- SOL SpA, Via Borgazzi 27 20900 Monza Italy
- Solenis Netherlands B.V., Pesetastraat 62 2991 XT Barendrecht Netherlands
- Solkanska industrija apna d.o.o., Cesta IX korpusa 106 5250 Solkan Slovenia
- Solvay Chemicals GmbH, HANS-BOECKLER-ALLEE 20 30173 HANNOVER Germany
- Solvay Chimica Italia S.p.A., VIA PIAVE 6 57016 Rosignano Marittimo (LI) Italy
- Solvay Sodi AD, Industrial Zone 9160 DEVNYA Bulgaria
- SPANIDOU SOULTANA, ELEFTHERIOU VENIZELOU 24 57008 NEA IONIA THESSALONIKI Greece
- Specialty Minerals, Freidrich-Haindl-Str 10 D86956 Schongau Germany
- Specialty Minerals France S.P.A.S, 2, Route d'Etagnac 87720 Saillat Sur Vienne Limousin France
- Specialty Minerals Nordic Oy Ab, Vahikkalantie 1 FIN-12400 Tervakoski Finland
- Specialty Minerals Poland sp.z.o.o, Ulica Lotnicza 1 82-550 Kwidzyn Poland
- Specialty Minerals Portugal, P.O Box 95 3080-801 Figueira de Foz Coimbra Portugal
- Specialty Minerals Slovakia spol. S.r.o, Tatranska cesta Vstup II 034 01 Ruzomberok Slovakia
- Speciálmész Kft., Károlyi István utca 27-29. 1041 Budapest Hungary
- Spyridon Liontos & SIA OE, BIPE Prevezas 48100 Preveza Greece
- Stadtwerke Mainz AG, Rheinallee 41 55118 Mainz Germany
- Stafford-Miller (Ireland) Limited, Clocherane Youghal Road _ Dungarvan Waterford Ireland
- Stamoulis Georgios, Marathokampos Samou 83102 Samos Greece
- Statiris Vasileios, 1o xlm P.E.O. Elassonas – Larisas 40200 Elassona Greece
- Stefanos Lymperis k SIA O.E., 5o xlm Chalkidas - Euvoia Mitika Lilantion 34100 Chalkida Euvoia Greece
- Stewardship Chemicals 35, Długosza 67 43-188 Orzesze Poland
- StonCor Europe, Rue du Travail, 9 1400 Nivelles Belgium
- Strandmøllen, Strandvejen 895 2930 Klampenborg Denmark
- Stroisnab 2003 EOOD , 7 Byalata skala str. 7 Byalata skala str. 4600 Velingrad Bulgaria Bulgaria
- STROITEL 2016 Ltd., 63 Pop Hariton str. 8895 Shivachevo district Sliven Bulgaria
- STROYCOM LTD, 15 st. st. Cyril and Methodius str. 15 st. st. Cyril and Methodius str. 8900 Nova Zagora Bulgaria Bulgaria
- SUPERSTROY ENGINEERING EOOD, 8A Bakston str. 8600 Yambol Bulgaria Bulgaria
- SURANYI-KUZSEL Tuzelo es Epitoanyag Kereskedes KKT., Haros u. 153 1222 Budapest Hungary
- Szedlár László Egyéni Vállalkozó, Debreceni u. 189. 4405 Nyíregyháza Hungary
- Szivek Ferencné Egyéni Vállalkozó, Napsugár u. 31. 2519 Piliscsév Hungary
- SÜDZUCKER AG, Marktbreiterstr. 74 97199 Ochsenfurt Germany
- TANEM - 77 - MT OOD, 75 Gumurdzinska str. 6800 Momchilgrad district Kardzhali Bulgaria
- TASSULLO MATERIALI S.p.A., VIA NAZIONALE,157 38010 TASSULLO TRENTO Italy
- TC NV OR1, Bergstraat 32 BE-3945 HAM Belgium
- Teplárna Trmice, a.s., Edisonova 453 400 04 Trmice Czech Republic
- Terzis Vasilios & SIA O.E., Parodos Tag/rhou Iliopoulou 2 58100 Giannitsa Greece
- Thermofisher Scientific Cork Ltd. , Currabinny P43 AY66 Carrigaline Co. Cork Ireland
- Thisted Mørtel- og grusværk, Kjeldstrupvej 59A Skovsted 7700 Thisted Denmark
- Thisted-Fjerritslev Cementvarefabrik A/S, Stevnsvej 17 7700 Thisted Denmark
- Tina 2 OOD, KOZLODUI 62 str. 6100 KAZANLAK district STARA ZAGORA Bulgaria
- TOP MIXT LTD, Str.Yuri Gagarin , bl.36, entr.G,fl.5,ap.86 2300 Pernik Bulgaria Bulgaria
- Toshevski EOOD, village Mikrevo,Strumyani Municipality 2826 village Mikrevo,Strumyani Municipality Blagoevgrad Bulgaria
- TOURAMANIS A -SPYROPOULOS A OE, KOURTZI-ALIFANTA PAGANI 81100 MYTILINI LESVOS Greece
- TRG Cyclamin GmbH, Hohendorfer Straße 20 39218 Schönebeck Germany
- TRZUSKAWICA S.A., Sitkówka 24 26-052 Nowiny Poland
- Tsixlaki S.A., Kyparisses, Myssiria 74100 Rethymno Kriti Greece
- U. S. Steel Košice, s.r.o., Vstupny areal U. S. Steel 04454 Košice Slovensko Slovakia
- Uljanik Tecnicki Plinovi d.o.o., Sv. Polikarpa 4 52100 Pula Croatia
- UNICALCE SPA, VIA TONIO DA BELLEDO, 30 23900 LECCO LECCO Italy
- V. Devetzoglou A.V.E.E., Thesi Tzaverdella Dimos Filis 13310 Athina Nomos Attikis Greece
- VACHA-LES LTD, 84 Targovska str. 84 Targovska str. 4210 Stamboliyski Bulgaria Bulgaria
- VAKABRNOCZ s.r.o., Jugoslavska 13 61300 Brno Czech Republic
- Vapenka Certovy schody a.s., Tman 200 CZ-26721 Tman Czech Republic
- VAR TRANS 81 EOOD, 24 Vestitelya str. 3000 Vratsa Bulgaria Bulgaria
- Vasileios & Aikaterini Kottaridi OE, 2nd km Kalamatas – Mesinnis Road Asprohoma 24100 Kalamata Greece
- Vasilikos Ioannis, Kardamada Vavili 82100 Chios Greece
- Vavilousakis Konstantinos, Parthenis Varvasi 82100 Chios Greece
- veerst moertelvaerk aps, Lykkegaardsvej 7 6600 Vejen Denmark
- Vejle Kalk og Mørtelværk A/S, Godthåbsvej 13 7100 Vejle Denmark
- Velestino Lime S.A., 14o xlm E.O. Volou - Larisas Thesi Katsairi 37500 Velestino Magnisia Greece
- Vemi Pro Ltd., Durvenica, bl. 2, entr. A, ap. 18 1756 Sofia Bulgaria
- Veolia Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
- Veolia WTS France, Immeuble L'Aquarène 1 place Montgolfier 94417 SAINT-MAURICE CEDEX France
- Verdalskalk AS, Kalkveien 40 7670 Inderøy Nord-Trøndelag Norway
- VETRA BETON, Niederlassung der Fertigbeton von Saldern GmbH & Co.KG, Hasseburger Straße 22 D-26603 Aurich Germany
- VILCA SPA, via Fornace 18/20 36021 Villaga VI Italy
- Violina Ltd, "St.Romil Vidinski" 91 3700 Vidin Bulgaria Bulgaria
- VISIJI Ltd., 4 Pazarska str. 6000 Stara Zagora Bulgaria Bulgaria
- Vodní sklo, a.s., Krakovská 1346/15 11001 Praha 1 Czech Republic
- Vognmand Kai Bartholomæussen, Sønderbyen 9 Lille Arden 9510 Arden Denmark
- VOLODIA VELIKOV OOD, 4, Mesta Str 7100 Ruse Bulgaria
- Vyncolit NV (OR SBJ), Wiedauwkaai 6 9000 Gent Belgium
- Vyncolit NV (OR SBNA), Wiedauwkaai 6 9000 Gent Belgium
- VÁPENKA VITOŠOV s.r.o., č.p. 54 78901 Hrabová Czech Republic
- w&p Kalk GmbH, Ferdinand-Jergitsch-Straße 15 9020 Klagenfurt Austria
- W. R. Grace S.A., 33 Route de Gallardon Boite Postale 39 28234 Epernon France
- Walhalla Kalk GmbH & Co KG, Donaustaufer Str. 207 93055 Regensburg Bayern Germany
- Wapiennik "Węże" Marian i Mirosław Wcisło, Węże 14 98-355 Działoszyn Poland
- Wewers Mørtel A/S, Centervænget 19 3400 Hillerød Denmark
- Wolfgang Endress GmbH & Co. KG; Kalk- und Schotterwerk, Bayreuther Straße 46 91322 Gräfenberg Bavaria Germany
- WSP Deutschland A.G. (OR12), Dingolfinger Straße 1-15 81673 Munchen Germany
- Wypał Wapna, Sobótka 27-530 Ożarów Świętokrzyskie Poland
- Xenarios Panagiotis, Marathi Tax. Thirida: 294 84600 Mykonos Greece
- Xorosan-95 OOD, Bulgaria 1A, str. 6560 Topolovgrad district Haskovo Bulgaria
- Yioi Chr. Alvanou O.E., Polichnitos 81300 Mytilini Greece
- YIOI STAM ATHANASIOU O.E., KRIEZA 34017 EYBOIA Greece
- YIOI TH. TSAROUHA & SIA O.E., Petroto Trikalon 0 42300 NEOCHORI Thessalia Greece
- Yioi Theod. Styliara O.E., Thesi Dyo Vouna 34100 Nea Artaki Eyvoia Greece
- Yordas GmbH, Äußere Nürnberger Str. 6 91301 Forchheim Germany
- Z. FOUSTERI A.FOUSTERIS O.E., Messaria Thiras PO Box 1431 84700 Messaria Thiras Nomos Kikladon Greece
- Zakład Wapienniczy "Hydrat" Marek Choła, ul. Krucza Góra 56 32-300 Olkusz Poland
- Zakład Wapienno Piaskowy MEGOLA M. Muda i wspólnicy Sp. J., Hedwiżyn 23-400 Biłgoraj Poland
- Zakłady Wapiennicze Lhoist S.A., ul. Wapiennicza 7 46-050 Tarnów Opolski Poland
- Zeiplast Chemical Industries Ltd, 23, Michali Zeipekki Str 4525 Moni Limassol Cyprus
- Zellstoff Pöls Aktiengesellschaft, Dr. Luigi-Angeli Straße 9 8761 Pöls Steiermark Austria
- Zement- und Kalkwerke Otterbein GmbH & Co. KG, Hauptstrasse 50 36137 Grossenlueder Hessen Germany
- Ziaka Maria, Louros 48061 Preveza Greece
- ZWA Eberswalde, Marienstraße 7 16225 Eberswalde Germany
- Zweckverband Landeswasserversorgung, Schützenstrasse 4 70182 Stuttgart Baden-Württemberg Germany
- Øzoral og Sydthy Mørtelverk, Oddesundvej 294 7760 Hurup Thy Nord Jylland Denmark
- БЕТИМ ЕООД, Mihail Takev 166 4550 Peshtera Pazardzhik Bulgaria
- ВЛАДИМИР ГЕГОВ - СТЕЛА, община Петрич 2874 с. Ново Кономлади Благоевград Bulgaria
- ДГ СТРОЙ ООД, Промишлена зона 2826 Микрево Bulgaria
- ЕВРОКВАРЦ - МВ ООД, 4 Tsar Samuil str., entr.G,ap.13 5800 Pleven Bulgaria Bulgaria
- Стройконсулт контрол ЕООД, ул. Младост 12 2800 Sandanski Bulgaria
- Строймат 2002 ЕООД, кв. Летище 50 6100 Казанлък Bulgaria
- ”Stambo 6 EОOD” , 32 doctor Hristo Tatarchev” str. 32 doctor Hristo Tatarchev” str. 2700 Blagoevgrad Bulgaria Bulgaria
- A. & A. Tsirigotis A.E., Thessalonikis 58 18233 Ag. Ioannis Rentis Nomos Attikis Greece
- AFOI SOULAKI O.E., Parodos Surrakou 48100 Preveza Greece
- Afoi Tsoutsi O.E, LOGGIDIA 48 100 PREVEZA Greece
- Air Products PLC, Hersham Place Technology Park Molesey Road KT12 4RZ Walton on Thames Surrey United Kingdom
- Andreas P. Tsiotas & SIA O.E., Katsika Ioanninon Thesi Fteri 45100 Katsika Ioanninon Greece
- Asvestolatomiki Ap. Sp. Doukeris & Yios EPE, Thesi Tzaverdella 19300 Ano Liosia Nomos Attikis Greece
- Balogh József EV, Dobó István u. 51. 7030 Paks Hungary
- BASF plc, Earl Road, P O Box 4 SK8 6QG Cheadle Hulme Cheshire United Kingdom
- BASF Schwarzheide GmbH, Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany
- Bezzeg Tibor Egyéni vállalkozó, 05/4 hrsz 8245 Vászoly Hungary
- Bodnár István egyéni vállalkozó, Zsellérerdő u. 31 2335 Taksony Hungary
- Borregaard AS as Only Representative 3, Hjalmar Wessels vei 6 1721 Sarpsborg Norway
- British Sugar plc, 1 Samson Place London Road PE7 8QJ Peterborough United Kingdom
- CAL.ME. S.P.A., Z. I. Marcellinara SS280km 16,7 88040 MARCELLINARA (CZ) Calabria Italy
- Calch Ty-Mawr Lime Ltd, Ty-Mawr Llangasty LD3 7PJ Brecon Powys United Kingdom
- Calestep s.l., Pozo de la albujea s/n 41560 Estepa Sevilla Spain
- Chalk Down Lime Ltd, The Lime Yard, Gate Farm Northiam Road TN32 5RP Staplecross East Sussex United Kingdom
- CIECH Soda Romania, 2, Uzinei Street 240050 Ramnicu Valcea Valcea Romania
- Cornish Lime Company Ltd, Brims Park Old Callywith Road PL31 2DZ Bodmin Cornwall United Kingdom
- D. SIGANOU & SIA E.E., Armyra N. Artaki 34600 Xalkida Greece
- Ecolime Limited, Southwood Farm Mowthorpe Terrington YO60 6PX York North Yorkshire United Kingdom
- Edilcalce Viola Olindo e Figli S.p.A., via Borgo S. Giovanni 11 06034 Foligno Italy
- Ekoagrostroy AD, 30 "A. Stamboliiski" str. 3400 Montana Bulgaria Bulgaria
- Electrabel S.A., Boulevard Simon Bolivar, 36 ENGIE Tower 1000 Bruxelles Belgium
- FORNACE CONTA S.R.L., FRAZIONE PRAMARZO 6 10080 BALDISSERO CANAVESE TORINO Italy
- FOTIOS DIMITRAKOPOULOS & SIA O.E., NEA EPARXIAKI ODOS BIPE THERIANO 25002 PATRA Greece
- GALLIOS MIX SA, 5,5 km Provincial Road Rethimnou Arkadiou 74100 Rethimno Greece
- Heritage Cob and lime, Coates Road Bideford Business Park EX39 4GD Bideford Devon United Kingdom
- I. SPARAKIS - A. STROYMPOYTAS O.E., Kato Alissos 25002 Kato Achaia Greece
- IAK APNO, proizvodnja apna, d.o.o., KRESNICE 14 1281 KRESNICE Slovenia
- IMERYS CARBONATES AUSTRIA GMBH, imerys PL253UR PAR CORNWALL United Kingdom
- Imerys Minerals Germany, Imerys Minerals GmbH Xantener Str. 237 47495 Rheinberg Rheinberg United Kingdom
- Impact Fluid Solutions (UK) Ltd, Ella Court Truro Business Park TR4 9PY Truro Cornwall United Kingdom
- J & J Sharpe Limited, Furzedon Merton EX20 3DS Okehampton Devon United Kingdom
- K. Monastirlis - AN. Georgiadou OE, Nea Kallikrateia 63080 Nea Kallikrateia Xalkidiki Greece
- K. Raikos & SIA Asvestopoiia Aspropyrgou O.E., Thesi Tzaverdella 19300 Aspropyrgos Nomos Attikis Greece
- K. Raikos & SIA Asvestopoiia Renti O.E., Tavrou 31 17778 Tavros Nomos Attikis Greece
- Kaklamanis Panagiotis, Mpatsi 84503 Andros Nomos Kikladon Greece
- kastaniotis bros - zahariadis s. abee, 1st km of Serres - Drama highway 62100 Serres Macedonia Greece
- KON/NOS EMMANOUILIDIS & SIA O.E., 2nd km KSANTHIS - KAVALAS 67100 KSANTHI Greece
- Kon/nos M. Raikos & SIA Asvestopoiia Peristeriou O.E., Antigonis 13 12133 Peristeri Nomos Attikis Greece
- Kon/nos Mich. Raikos & SIA Latomeia Neas Pentelis O.E., Chrys. Smyrnis 6 15121 Pefki Nomos Attikis Greece
- Kouravanas Dimitrios & SIA OBEE, Imvrou & Aidiniou Nea Magnisia 35100 Lamia Greece
- L OREAL UK LTD, 255, Hammersmith Road W6 8AZ LONDON United Kingdom
- LANTOURIS STAVROS, TSIMANDRA 81400 LIMNOS Greece
- Limeslake Limited, Walronds Park Isle Brewers TA3 6QP Taunton Somerset United Kingdom
- MATHIOPOULOS DIMITRIOS, ANO DIMINIO 20200 ANO DIMINIO KORINTOS Greece
- Messer Slovenija d.o.o., Jugova 20 2342 Ruše Slovenia
- Mike Wye and Associates Limited, Buckland Filleigh Sawmills Buckland Filleigh EX21 5RN Beaworthy Devon United Kingdom
- Minteq UK Limited, Broadgate Tower, Third floor 20 Primrose Street EC2A 2RS London United Kingdom
- NUOVA ITAL-LEGANTI S.R.L., via della Vittorina n. 60 06024 Gubbio (PG) Umbria Italy
- NYKØBING FLISE- OG MØRTELFABRIK A/S, c/o T.C.T. Holding ApS Stevnsvej 17, Sennels 7700 Thisted Denmark
- Papalexis Aggelos, Agios Nikolaos 63078 Sithonia Chalkidiki Greece
- Pastroumatzi Panagi, Nikolaou Plastira 65 54250 Charilaou/Thessaloniki Nomos Thessalonikis Greece
- Rose of Jericho (Lime) Ltd, Horchester Farm Holywell DT2 0LL Dorchester Dorset United Kingdom
- RÖCKL ISTVÁN Egyéni Vállalkozó, Erzsébet út 42. 6523 Csátalja Hungary
- S. Doukeri & SIA O.E., Terma Megalou Alexandrou 13341 Ano Liosia Nomos Attikis Greece
- S.C. PRESCON BV SA BRASOV, str. Poienelor nr.5 500419 Brasov Center Region / Brasov county Romania
- SEGURA, S.L., Mina Matagallar, s/n 41566 Pedrera Sevilla Spain
- SIAD Società Italiana Acetilene & Derivati S.p.A., via San Bernardino n. 92 24126 Bergamo Lombardia Italy
- Specialty Minerals GmbH, Dr. Willhelm-Roelen-Str. 129 47179 Duisburg North Rhine-Westphalia Germany
- Tata Chemicals Europe Limited, Natrium House Winnington Lane CW8 4GW Northwich Cheshire United Kingdom
- THEOFANIS PAGOURELIAS, TERMA TAXIARHON 38446 VOLOS GREECE Greece
- Tornby Mørtelværk, Hornevej 4 Tornby 9850 Hirtshals Denmark
- Tsavdaridis K. & SIA O.E., 10o xlm Kozanis - Thessalonikis 50100 Periohi Drepanou Greece
- UAB „APLINKOS VADYBA“, Vilkpėdės g. 22 03151 Vilnius Lithuania
- VAGA srl, SP199 - loc. Sostegno 27010 Costa de' Nobili Italy
- Vasiliki V. Markaki, 1o xlm Atalantis - Skalas 35200 Atalanti Greece
- VASILIOU STAVROS, BASILIKO 34100 XALKIDA Greece
- Vincze István Egyéni Vállalkozó, Kossuth L. u. 3. 6414 Pirtó Hungary
- Westfalen AG, Industrieweg 43 D-48155 Münster Germany
- Xenarios Panagiotis, Marathi Tax. Thirida: 294 84600 Mykonos Greece
Substance names and other identifiers
This section displays all the public names and other identifiers available in ECHA's databases for the substance.
Regulatory process names gives the names under which the substance appears in ECHA's regulatory processes and lists.
Translated names gives the names in different EU languages, where available to ECHA. Note that translated names are available at this time only for substances which have a harmonised C&L or which are approved Biocidal active substances.
CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available.
IUPAC names gives all the non-confidential names provided to ECHA in submissions under REACH, CLP, BPR and PIC, where indicated to be a IUPAC name. Note that this does not mean that they are properly structured names according to the IUPAC nomenclature. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. Therefore the quality of these names may be variable.
Trade names gives all public trade names submitted to ECHA in REACH registrations.
Other names gives any names of any other type, such as common names, synonyms and acronyms.
Other identifiers gives any other non-name identifiers available for ths substance. For example CLH index numbers, CN numbers, deleted CAS numbers, etc.
The data presented in these sections has been cleaned to remove names of one character or less, or names which consist solely of punctuation or numerical characters.
Scientific properties
This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Appearance/physical state / colour
This section summarises appearance, physical state and colour property values from all registered dossiers held in the ECHA database for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered from most to least commonly provided, with the percentage of provided values appended. The percentage is based on the count of values provided.
Physical state
For substance’s physical state at 20°C and 1 013 hPa, registrants can classify their substance as:
- Solid
- Liquid
- Gaseous
Form
For substance’s form, registrants can classify their substance as:
- Aerosol dispenser: not specified
- Aerosol dispenser: foam aerosol
- Aerosol dispenser: spray aerosol
- Gas
- Gas: vapour
- Gas under pressure: compressed gas
- Gas under pressure: dissolved gas
- Gas under pressure: liquefied gas
- Gas under pressure: refrigerated liquefied gas
- Liquid
- Liquid: viscous
- Liquid: volatile
- Liquid – liquid: emulsion
- Liquid – solid: mixture of
- Semi–solid (amorphous): gel
- Solid
- Solid: bulk
- Solid: compact
- Solid: crystalline
- Solid: fibres
- Solid: filaments
- Solid: flakes
- Solid: granular
- Solid: pellets
- Solid: particulate/powder
- Solid: nanomaterial, surface–treated
- Solid: nanomaterial, no surface treatment
- Solid: nanomaterial
- Solid – liquid: aqueous solution
- Solid – liquid: suspension
- Solid – solid: alloy
- Aerosol
- Compact
- Crystalline
- Dispersion
- Fibre
- Filaments
- Flakes
- Liquefied gas
- Nanomaterial
- Particulates
- Paste
- Pellets
- Powder
- Refrigerated liquid
- Suspension
- Viscous
- Other
- No data
Odour
For substance’s odour, registrants can classify their substance as:
- Ammonia-like
- Biting
- Characteristic of sulphur containing compounds
- Characteristic of aromatic compounds
- Faint
- Garlic-like
- Odourless
- Pungent
- Slight
- Sweetish
- Other
Type
For substance’s type, registrants can classify their substance as:
- Element
- Inorganic
- Natural substance
- Organic
- Organometallic
- Petroleum product
- Other
Summary
Summary data is collected from the endpoint summary(ies) provided by registrants of REACH dossiers.
Physical state at 20°C and 1013 hPa
For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as:
- Solid
- Liquid
- Gaseous
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications.
Study results
- 20 studies submitted
- 7 studies processed
- C Physical state at 20°C and 1013 hPa
- Solid (100%) [7]
- C Form
- Powder (71%), Crystalline (29%) [7]
- C Odour
- Odourless (86%), Other (14%) [7]
- C Substance type
- Inorganic (100%) [7]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 5 | |||
Supporting study | 9 | 4 | ||
Weight of evidence | 2 | |||
Other |
Data waiving | |
---|---|
no waivers |
C Summaries
- 2 summaries submitted
- 1 summary processed
- Physical state at 20°C and 1013 hPa
- Solid (100%)
Melting/freezing point
This section summarises the melting and freezing point values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Melting / freezing point provides substance information on the melting/freezing point in °C at a pressure measured in Pa.
Results without measurement conditions (pressure) are not processed for the Brief Profile. Additionally, if registrants select ‘other’ as a unit of measure for pressure, the measurement conditions (and therefore the study results) cannot be processed in the Brief Profile.
Summary
Melting/freezing point at 101 325 Pa provides information on the substance melting/freezing point in °C at a pressure of 101 325 Pa.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications.
Study results
- 14 studies submitted
- 3 studies processed
- R Melting / freezing point
- 450 - 580 °C @ 101.3 kPa [3]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 5 | 6 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Boiling point
This section summarises the boiling point values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header .
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C).
Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C.
Density provides substance information on the density in grams per (centi)metre at a temperature measured in °C.
Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C.
Tap density provides substance information on the bulk density per grams per millilitre at a temperature measured in °C.
Note: Registrants can also select ‘other’ as the type of density. If so, the data provided is not processed for the Brief Profile.
Summary
Relative density at 20 °C provides information on the substance relative density at 20 °C. If more than one value is found for this section, the range of min-max values will be displayed here.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data-waving justifications.
Study results
- 9 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 6 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 3 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Density
This section summarises the density values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C).
Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C.
Density provides substance information on the density in grams per (centi)metre at a temperature measured in °C.
Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C.
Tap density provides substance information on the bulk density per grams per millilitre at a temperature measured in °C.
Note: Registrants can also select ‘other’ as the type of density. If so, the data provided is not processed for the Brief Profile.
Summary
Relative density at 20 °C provides information on the substance relative density at 20 °C. If more than one value is found for this section, the range of min-max values will be displayed here.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 13 studies submitted
- 5 studies processed
- R Relative density
- 2.22 - 2.26 @ 20 - 22.5 °C [5]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 5 | |||
Supporting study | 4 | |||
Weight of evidence | 4 | |||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 1 summary submitted
- 1 summary processed
- Relative density at 20°C
- 2.22
Vapour pressure
This section summarises the vapour pressure values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C.
Note: Registrants can also select ‘other’ as the unit of measure for pressure. If so, the pressure data provided is not processed for the Brief Profile.
Summary
Vapour pressure provides substance information on the vapour pressure in Pa at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and data waving justifications.
Study results
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 3 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Partition coefficient
This section summarises the partition coefficient values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH.
Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH.
Summary
Log Pow (Log Kow) provides substance information on the partition coefficient type Log Pow (Log Kow) at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications
Study results
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 3 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Water solubility
This section summarises the water solubility values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. Values provided in ppb and Vol% are provided separately.
Summary
Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 12 studies submitted
- 3 studies processed
- R Water solubility (mass/vol.)
- 999 - 1 844.9 mg/L @ 20 °C and pH 12.4 [4]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 6 | 3 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 1 summary submitted
- 1 summary processed
- Water solubility
- 1.845 g/L @ 20 °C
Solubility in organic solvents / fat solubility
Study results
If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Solubility provides substance information on the substance’s solubility in organic solvents/fat in grams per litre at a temperature measured in °C. Registrants can provide data for one or more of the following picklist options:
- Standard fat
- Acetone
- Acetonitrile
- Benzene
- N-butanol
- Cyclohexane
- Diethyl ether
- Diethyl ketone
- Dimethylformamide
- DMSO, ethanol
- Ethyl acetate
- Isopropanol
- Methanol
- N-octanol
- Toluene
Note: Registrants can also select ‘other’ as the solvent. If so, the data provided is not processed for the Brief Profile.
Also, if the registrant selects the ‘mg/100 g solvent’; ‘g/kg solvent’; ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure, the data provided will not be processed for the Brief Profile.
Summary
Solubility in mg/100g standard fat at 20°C provides substance information on the substance solubility in standard fat in milligram per 100 gram at a temperature of 20°C.
Solubility in organic solvents at 20°C provides substance information on the substance solubility in organic solvents in gram per litre at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Surface tension
This section summarises the surface tension values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Surface tension provides substance information on the surface tension in (milli)Newton per metre in a concentration in (milli)gram per metre and at a temperature measured in °C.
Note: Results without a concentration value are not processed for the Brief Profile.
Also, if the registrant selects ‘ppb’; ‘vol%’ and ‘other’ as a unit of measure for the concentration value, the data provided will not be processed for the Brief Profile.
Summary
Surface tension at 20°C provides substance information on the surface tension in (milli)Newton per metre in a concentration in (milli)gram per metre, at a temperature of 20 °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 1 study processed
- R Surface tension
- 72 mN/m @ 1 g/L and 20 °C [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 2 |
R Summaries
- 1 summary submitted
- 1 summary processed
- Surface tension at 20 °C
- 72 mN/m @ 1 000 mg/L
Flash point
This section summarises the flash point values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one result is available per endpoint, the range of results (min-max, RANGE method) will be presented.
Flash point provides substance information on the substance’s flash point at a temperature measured in °C at a pressure measured in Pascal.
Summary
Flash point at 101 325 Pa provides substance information on the substance’s flash point at a temperature measured in °C at a pressure of 101 325 Pascal.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 3 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Auto flammability
This section summarises the auto flammability values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Autoflammability / Self-ignition provides substance information on the substance’s self-ignition temperature in °C at a pressure measured in Pascal.
Note: Registrants can also select ‘other’ as the unit of measure for pressure. If so, the pressure data provided is not processed for the Brief Profile.
Summary
Autoflammability / Self-ignition at 101 325 Pa provides substance information on the substance’s self-ignition temperature in °C at a pressure of 101 325 Pa.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 2 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Flammability
This section summarises the flammability values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Applicant’s summary and conclusion – Interpretation of results. Registrants can register their substance flammability as:
- Extremely flammable aerosols (Cat. 1)
- Flammable gases (Cat.1)
- Flammable solids (Cat.1)
- Pyrophoric liquids (Cat.1)
- Pyrophoric solids (Cat. 1)
- Self-heating substances and mixtures (Cat. 1)
- Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.1)
- Flammable aerosols (Cat.2)
- Flammable gases (Cat.2)
- Flammable solids (Cat.2)
- Self-heating substances and mixtures (Cat.2)
- Substances or mixtures which in contact with water release flammable gases which may ignite spontaneously (Cat.2)
- Non-flammable aerosols (Cat.3)
- Substances or mixtures which in contact with water releases flammable gases (Cat.3)
- Chemically unstable gases (Cat.A)
- Chemically unstable gases (Cat.B)
- GHS criteria not met
- Not classified based on GHS criteria
- Extremely flammable
- Extremely flammable liquefied gas
- Substances and mixtures which in contact with water emit flammable gases
- Contact with water liberates highly flammable gases
- Highly flammable
- Flammable
- Pyrophoric
- Spontaneously flammable in air (pyrophoric)
- Non–flammable
- Non flammable (based on GHS criteria)
- No information available
- Not classified
Note: Registrants can also select ‘other’ as the flammability value for their substance. If so, the data provided is not processed for the Brief Profile.
Summary
Registrants can register their substance’s flammability as:
- Extremely flammable
- Extremely flammable liquefied gas
- Contact with water liberates highly flammable gases
- Highly flammable
- Flammable
- Spontaneously flammable in air (pyrophoric)
- Non–flammable
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 13 studies submitted
- 1 study processed
- C Interpretation of results
- Non flammable (100%) [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 3 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 9 |
Exposure cons. | |
Other |
C Summaries
- 1 summary submitted
- 1 summary processed
- Flammability
- Not classified (100%)
Explosiveness
This section summarises the explosiveness values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Applicant’s summary and conclusion – Interpretation of results. Registrants can register their substance explosiveness as:
- Unstable explosive
- Mass explosion hazard (Div. 1.1)
- Projection hazard but not a mass explosion hazard (Div. 1.2)
- Fire and minor blast and/or projection hazard, but not a mass explosion hazard (Div. 1.3)
- No significant hazard (Div. 1.4)
- Very insensitive substances with mass explosion hazard (Div. 1.5)
- Extremely insensitive which do not have a mass explosion hazard (Div. 1.6)
- GHS criteria not met
- Explosive
- Non explosive
Summary
Explosiveness. Registrants can register their substance explosiveness as:
- Explosive
- Non explosive
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 2 |
C Summaries
- 1 summary submitted
- 1 summary processed
- Explosiveness
- Non-explosive (100%)
Oxidising
This section summarises the oxidising values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Applicant’s summary and conclusion – Interpretation of results. Registrants can register their substance’s oxidising properties as:
- no oxidising properties
- oxidising: maximum burning rate equal or higher than reference mixture
- oxidising: vigorous reaction in preliminary test
- oxidising;
- test not applicable because organic peroxide.
Note: Registrants can also select ‘other’ as the oxidising value for their substance. If so, the data provided is not processed for the Brief Profile.
Summary
Oxidising. Registrants can register their substance oxidising properties as:
- Oxidising
- Yes
- Non oxidising
- No
- No information available
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 3 |
C Summaries
- 1 summary submitted
- 1 summary processed
- Oxidising
- Non oxidising (100%)
Oxidation reduction potential
This section summarises the oxidation reduction potential values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Oxidation reduction potential in mV provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature measured in °C.
Summary
Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
pH
This section summarises the pH values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre.
Note: Results without a concentration value are not processed for the Brief Profile.
Summary
For this endpoint registrants do not provide summary data.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Dissociation constant
This section summarises the dissociating values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Dissociating Properties provides substance information by picklist values:
- Yes
- No
- Ambiguous
- Not determined
Dissociation Constant provides numerical substance information on the substance’s dissociation constant values at a temperature measured in °C.
Summary
pKa at 20°C provides numerical substance information on the dissociation constant in pKa at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 1 study processed
- C Dissociating properties
- Not determined (100%) [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | 1 |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
R Summaries
- 1 summary submitted
- 1 summary processed
- pKa at 20 °C
- 12.6
Viscosity
This section summarises the viscosity values from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min–max) and range of experimental conditions will be presented (RANGE method).
Registrants can report substance information on viscosity as:
- Dynamic viscosity (in mPa s)
- Kinematic viscosity (in mm²)/s)
- Flow time (in s) – ASTM Cup 1
- Flow time (in s) – ASTM Cup 2
- Flow time (in s) – ASTM Cup 3
- Flow time (in s) – ASTM Cup 4
- Flow time (in s) – 3 mm ISO cup
- Flow time (in s) – 4 mm ISO cup
- Flow time (in s) – 5 mm ISO cup
- Flow time (in s) – 6 mm ISO cup
- Flow time (in s) – other:
Summary
Static viscosity at 20°C provides substance information on the substance’s (static) viscosity per square millimetre per second at a temperature of 20°C.
Dynamic viscosity at 20°C provides substance information on the substance’s (dynamic) viscosity per millipascal second at a temperature of 20°C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | 2 |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Phototransformation in air
This section summarises the values related to phototransformation in air from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max, RANGE method) will be displayed.
Dissipation half-life provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year.
Degradation rate constant (OH Radicals) provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1.
Degradation rate constant (Ozone) provides substance information on the substance’s degradation rate constant with Ozone as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1.
Note: Registrants can also select ‘other’ as a reaction type for the degradation rate constant of the substance. If so, the data provided is not processed in the Brief Profile.
Summary
Half-life in air provides substance information on the substance’s dissipation half-life in air in seconds/minutes/hours/days/weeks/months/years.
Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Hydrolysis
This section summarises the values related to hydrolysis from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: Results without a measurement condition (temperature) are not processed for the Brief Profile.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 2 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Phototransformation in water
This section summarises the values related to phototransformation in water from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year.
Summary
Phototransformation in water provides information on the substance’s phototransformation in water in seconds/minutes/hours/days/weeks/months/years.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Phototransformation in soil
This section summarises the values related to phototransformation in soil from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Dissipation Half-life of parent compound provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year.
Summary
Phototransformation in soil provides substance information on the substance’s phototransformation in soil in seconds/minutes/hours/days/weeks/months/years.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Biodegradation in water - screening tests
This section summarises the values related to the screening tests for biodegradation in water from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
BOD5 provides substance information on the substance’s BOD5 values displayed in O2 (milli)gram per gram test material.
COD provides substance information on the substance’s COD values displayed in O2 (milli)gram per gram test material.
BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material.
BOD5/COD ratio provides substance information on the substance’s BOD5/COD ratio values displayed in O2 (milli)gram per gram test material.
BOD5/ThOD ratio provides substance information on the substance’s BOD5/ThOD ratio values displayed in O2 (milli)gram per gram test material.
BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material.
ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material.
Note: Registrants can also select ‘other’ as the unit of measure. If so, the data provided is not processed for the Brief Profile.
Applicant’s summary and conclusion – Interpretation of results provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options:
- Readily biodegradable
- Readily biodegradable but failing the 10-day window
- Inherently biodegradable
- Inherently biodegradable, fulfilling specific criteria;
- Inherently biodegradable, not fulfilling specific criteria
- Not inherently biodegradable
- Not readily biodegradable
- Under test conditions no biodegradation observed
Note: Registrants can also select ‘other’ as picklist option for describing the biodegradation values of the substance in water. If so, the data provided is not processed in the Brief Profile.
Summary
Biodegradation in water provides information on the substance’s biodegradation properties in water and can be registered by the registrants by one or more of the following picklist options:
- Readily biodegradable
- Readily biodegradable but failing the 10-day window
- Inherently biodegradable
- Inherently biodegradable, fulfilling specific criteria;
- Inherently biodegradable, not fulfilling specific criteria
- Under test conditions no biodegradation observed
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 3 |
Exposure cons. | |
Other | 1 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Biodegradation in water & sediment - simulation tests
This section summarises the values related to the simulation tests for biodegradation in water and sediments from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Half-life in water provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: If a temperature value is not provided by the registrant, the information on half-life in water will not be processed for the Brief Profiles.
Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: Results without a measurement condition (temperature) are not processed for the Brief Profile.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 0 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Biodegradation in soil
This section summarises the values related to biodegradation in soil from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Half-life in soil provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.
Note: Results without a measurement condition (temperature) are not processed for the Brief Profile.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | 1 |
Sci. unjustified | 3 |
Exposure cons. | |
Other |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Bioaccumulation: aquatic / sediment
This section summarises the values related to aquatic/sediment bioaccumulation in all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Bioaccumulation factor (aquatic species) provides substance information on the substance’s bioaccumulative properties not taking account the dimensions.
Bioaccumulation Factor (aquatic species) L/kg ww provides substance information on the substance’s bioaccumulative properties for aquatic species measured in litre per kilogram (wet weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 4 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Bioaccumulation: terrestrial
This section summarises the values related to terrestrial bioaccumulation in all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary data
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions.
Bioaccumulation Factor (terrestrial species) L/kg ww provides substance information on the substance’s terrestrial bioaccumulative properties measured in litre per kilogram (wet weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 2 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 1 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Adsorption/desorption
This section summarises the values related to adsorption/desorption from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Log Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Log Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon.
Note: If the measurement condition (percentage of organic carbon) is not provided by the registrant for adsorption coefficient Kd, the data provided is not processed for the Brief Profile.
Summary
Koc at 20°C provides substance information on the substance’s Koc adsorption at a temperature 20 °C.
Log Koc at 20°C provides substance information on the substance’s log Koc adsorption at a temperature 20 °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 6 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | 2 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | 2 |
Sci. unjustified | |
Exposure cons. | |
Other | 1 |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Henrys law constant (H)
This section summarises the values related to Henry’s law constant (H) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Henry’s law constant can be presented as different types, depending on the units chosen:
H dimensionless provides substance information on the substance’s Henry’s Law Constant (dimensionless) at a temperature measured in °C and a pressure measured in Pascal.
H dimensionless volumetric basis provides substance information on the substance’s Henry’s Law Constant in dimensionless volumetric basis at a temperature measured in °C and a pressure measured in Pascal.
H atm provides substance information on the substance’s Henry’s Law Constant in atm at temperature measured in °C and a pressure measured in Pascal.
H atm m3/mol provides substance information on the substance’s Henry’s Law Constant in atm m3/mol at a temperature measured in °C and a pressure measured in Pascal.
H Pa m3/mol provides substance information on the substance’s Henry’s Law Constant in Pa m3/mol at a temperature measured in °C and the atmospheric pressure measured in Pascal.
Note: Registrants can also select ‘other’ as the type of Henry’s law constant. If so, the data provided is not processed for the Brief Profile.
Summary
Henry’s Law Constant provides substance information on the substance’s Henry’s Law Constant measured in in Pa.m3.mol-1 at a temperature measured in °C.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Distribution modelling
This section summarises the values related to distribution modelling from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of values (provided in %).
Percentage distribution in the Media displays the values attributed by the registrants to the following options:
- air
- water
- soil
- sediment
- suspended sediment
- biota
- aerosol
Summary
For this endpoint registrants do not provide summaries that are processable for the Brief Profile.Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Predicted No-Effect Concentration (PNEC)
If more than one numerical result is available per endpoint, the range of results (min-max) will be presented (RANGE method).
Hazard to aquatic organisms provides information on the substance’s hazard assessment conclusion regarding aquatic organisms.
Manufacturers and importers can provide the following information in the registration dossier:
Freshwater/marine water/intermittent:
- PNEC aqua, displayed in milligram per litre.
- No data: aquatic toxicity unlikely
- No data available: testing technically not feasible
- No hazard identified
Sewage treatment plant (STP)
- PNEC STP, data displayed in milligram per litre.
- No data: aquatic toxicity unlikely
- No data available: testing technically not feasible
- No emission the STP expected
- No hazard identified
Sediment freshwater/marine water
- PNEC sediment, data displayed in milligram per kilo sediment (dry weight).
- No or insufficient data available at present
- No exposure of sediment expected
- No data available: testing technically not feasible
- No hazard identified
Hazard for Air provides information on the substance’s hazard assessment conclusion related to air.
Data is generally standardised and displayed in milligram per litre/cubic metre.
Manufacturers and importers can provide the following information in the registration dossier:
- PNEC air
- Hazard related to composition of atmosphere identified
- No hazard identified
Hazard for terrestrial organisms provides information on the substance’s hazard assessment conclusion related to terrestrial organisms/soil.
Data is generally standardised and displayed in milligram per kilo soil (dry weight).
Manufacturers and importers can provide the following information in the registration dossier:
- PNEC soil
- No or insufficient data available at present
- No exposure of soil expected
- No data available: testing technically not feasible
- No hazard identified
Hazard for predators provides information on the substance’s hazard assessment conclusion related to predators/secondary poisoning.
Data is generally standardised and displayed in in milligram per kilo of food.
Manufacturers and importers can provide the following information in the registration dossier:
- PNEC oral
- No potential for bioaccumulation
- No potential to cause toxic effects if accumulated (in higher organisms) via the food chain
- No or insufficient data available at present
- No data available: testing technically not feasible
R Summaries
- 1 summary submitted
- 1 summary processed
The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.
Hazard for Aquatic Organisms | |
---|---|
Freshwater | 490 µg/L (1) |
Intermittent releases (freshwater) | 490 µg/L (1) |
Marine water | 320 µg/L (1) |
Intermittent releases (marine water) | - |
Sewage treatment plant (STP) | 3 mg/L (1) |
Sediment (freshwater) | Insufficient data available (further information necessary) (1) |
Sediment (marine water) | Insufficient data available (further information necessary) (1) |
Hazard for Air | |
---|---|
Air | No hazard identified (1) |
Hazard for Terrestrial Organism | |
Soil | 1.08 g/kg soil dw (1) |
Hazard for Predators | |
Secondary poisoning | No potential for bioaccumulation (1) |
Short–term toxicity to fish
This section summarises the values related to short–term toxicity to fish from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). The five highest priority groupings of provided data are displayed in milligram per litre or molar per litre.
Prioritisation by dose descriptor:
- LC50
- LC0
- LC100
- LC10
- EC50
- EC0
- EC100
- EC10
- NOEC
- LOEC
- LL50
- LL0
- LL100
- LL10
- EL50
- EL0
- EL100
- EL10
- IC50
- IC10
- IC100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
LC50 for freshwater fish provides substance information on the substance’s lethal concentration for 50% of the freshwater fish in the test, displayed in milligram per litre.
LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 11 studies submitted
- 2 studies processed
- P/RResults
- LC50 (4 days) 50.6 - 457 mg/L [2]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other | 8 |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Long–term toxicity to fish
This section summarises the values related to long term toxicity to fish from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- IC10
- EC50
- LC50
- IC50
- EL10
- EL50
- LL10
- LL50
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC10 / LC10 or NOEC for freshwater fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 1 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Short–term toxicity to aquatic invertebrates
This section summarises the values related to short term toxicity to aquatic invertebrates from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- LC50
- EC0
- LC0
- EC100
- LC100
- LC10
- EC10
- NOEC
- LOEC
- LL50
- LL0
- LL100
- LL10
- EL50
- EL0
- EL100
- EL10
- IC10
- IC100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
LC50 for freshwater invertebrates provides substance information on the substance’s lethal concentration for 50% of the freshwater invertebrates in the test, displayed in milligram per litre.
LC50 for marine water invertebrates provides substance information on the substance’s lethal concentration for 50% of the marine water invertebrates in the test, displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 5 studies submitted
- 4 studies processed
- P/RResults
- EC50 (48 h) 49.1 mg/L [1]
- LC50 (4 days) 158 mg/L [1]
- LC50 (48 h) 1.83 g/L [2]
- EC100 (48 h) 75 mg/L [1]
- NOEC (48 h) 33.3 mg/L [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | 2 | ||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Long–term toxicity to aquatic invertebrates
This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- IC10
- EC50
- LC50
- IC50
- EL10
- EL50
- LL10
- LL50
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC10 / LC10 or NOEC for freshwater invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater invertebrates or the no observed effect concentration for freshwater invertebrates. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre.
EC10 / LC10 or NOEC for marine water invertebrates provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water invertebrates or the no observed effect concentration for marine water invertebrates. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 3 studies processed
- P/RResults
- NOEC (14 days) 32 mg/L [2]
- EC50 (21 days) 610 mg/L [2]
- LC50 (14 days) 53.1 mg/L [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | 2 | ||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to aquatic algae and cyanobacteria
This section summarises the values related to toxicity to aquatic algae and cyanobacteria from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- NOEC
- LOEC
- EC10
- IC10
- EC20
- EC5
- EC0
- EC100
- IC100
- EC90
- EL0
- EL5
- EL10
- EL20
- EL50
- EL90
- EL100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
LC50 for freshwater algae provides substance information on the substance’s lethal concentration for 50% of the freshwater algae in the test, displayed in generally milligram per litre.
LC50 for marine water algae provides substance information on the substance’s lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre.
EC10 / LC10 or NOEC for freshwater algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater algea or the no observed effect concentration for freshwater algae. Values are generally displayed in milligram per litre.
EC10 / LC10 or NOEC for marine water algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water algae or the no observed effect concentration for marine water algae. Values are generally displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 6 studies submitted
- 1 study processed
- P/RResults
- EC50 (72 h) 184.57 mg/L [1]
- NOEC (72 h) 48 mg/L [1]
- LOEC (72 h) 80 mg/L [1]
- EC10 (72 h) 79.22 mg/L [1]
- EC20 (72 h) 106.02 mg/L [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other | 2 | 2 |
Data waiving | |
---|---|
no waivers |
R Summaries
- 1 summary submitted
- 1 summary processed
- EC50 for freshwater algae
- 184.57 mg/L
- EC10 or NOEC for freshwater algae
- 48 mg/L
Toxicity to aquatic plants other than algae
This section summarises the values related to toxicity to aquatic plants (other than algae) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally standardised and the displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- NOEC
- LOEC
- EC10
- IC10
- EC20
- EC5
- EC0
- EC100
- IC100
- EC90
- EL0
- EL5
- EL10
- EL20
- EL50
- EL90
- EL100
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC/LC50 for freshwater plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the freshwater plants in the test, generally displayed in milligram per litre.
EC50/LC50 for marine water plants provides substance information on the substance’s effect concentration or lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre.
EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. Values are generally displayed in milligram per litre.
EC10 / LC10 or NOEC for marine water plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water plants or the no observed effect concentration for marine water plants. Values are generally displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Toxicity to microorganisms
This section summarises the values related to toxicity to microorganisms from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per litre or molar per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- EC50
- IC50
- NOEC
- LOEC
- EC10
- IC10
- EC0
- IC0
- EC100
- IC100
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre.
EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. Values are generally displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 2 studies submitted
- 1 study processed
- P/RResults
- EC50 (3 h) 300.4 mg/L [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
R Summaries
- 1 summary submitted
- 1 summary processed
- EC50 for microorganisms
- 300.4 mg/L
Sediment toxicity
This section summarises the values related to toxicity to sediment toxicity from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram sediment (dry weight) or in milligram per litre.
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- LD10
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LR10
- LR50
- LR0
- LR100
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram sediment (dry weight).
EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram sediment (dry weight).
EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. Values are generally displayed in milligrams per kilogram (dry weight).
EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Values are generally displayed in milligrams per kilogram (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 2 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 1 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Endocrine disrupter testing in aquatic vertebrates – in vivo
This section summarises the values related to endocrine disrupter testing in aquatic vertebrates from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per litre.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter).
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- IC10
- EC50
- LC50
- IC50
- EL10
- EL50
- LL10
- LL50
- NOELR
- LOELR
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC10 / LC10 or NOEC for freshwater fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. Values are displayed in milligram per litre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Toxicity to terrestrial macroorganisms except arthropods
This section summarises the values related to toxicity to soil macroorganisms (except arthropods) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare.
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- LD10
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LR10
- LR50
- LR0
- LR100
Prioritisation by units (dry weight):
- Mg/cm2
- g/ha
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
EC/LC50 for freshwater sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the freshwater sediment, generally displayed in milligrams per kilogram (dry weight).
EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram (dry weight).
EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. Values are generally displayed in milligrams per kilogram (dry weight).
EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. . Values are generally displayed in measured in (nano/ micro/milli)gram per kilogram (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 4 studies submitted
- 1 study processed
- P/RResults
- NOEC (28 days) 2 - 5 g/kg soil dw [2]
- EC50 (28 days) 4.18 g/kg soil dw [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 2 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
R Summaries
- 1 summary submitted
- 1 summary processed
- Long-term EC10 / LC10 / NOEC
- 2 g/kg soil dw
Toxicity to terrestrial arthropods
This section summarises the values related to toxicity to (terrestrial) arthropods from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by unit.
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- LD10
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LR10
- LR50
- LR0
- LR100
Prioritisation by unit:
- soil dw (g/ha and mg/cm²)
- soil ww; (g/ha and mg/cm²)
- µg per animal
- mL/ha; mg/kg bw
- mg/kg diet
- ppm
- mg/kg dung dw
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the soil dwelling arthropods in the test, generally displayed in milligram per kilo soil (dry weight).
Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. Values are generally displayed in milligram per kilo soil (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other | 1 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Toxicity to terrestrial plants
This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance.
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- LOEC
- EC10
- LC10
- EC50
- LC50
- EC0
- EC25
- EC100
- LC0
- LC25
- LC100
- ER0
- ER10
- ER25
- ER50
- ER100
Prioritisation by units:
- soil dw (g/ha, kg/ha and lbs/acre).
- soil ww (g/ha, kg/ha and lbs/acre).
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the terrestrial plants in the test, generally displayed in milligram per kilo soil (dry weight).
Long-term EC10 or LC10 or NOEC for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the terrestrial plants in the test, or the no observed effect concentration for terrestrial plants. Values are generally displayed in milligram per kilo soil (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 1 study processed
- P/RResults
- NOEC (21 days) 1.08 - 2.27 g/kg soil dw [6]
- LOEC (21 days) 2.27 - 4.76 g/kg soil dw [6]
- EC50 (21 days) 2.67 - 6.18 g/kg soil dw [7]
- LC50 (21 days) 10.83 g/kg soil dw [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
R Summaries
- 1 summary submitted
- 1 summary processed
- Long-term EC10 / LC10 / NOEC
- 1.08 g/kg soil dw
Toxicity to soil microorganisms
This section summarises the values related to toxicity to soil microorganisms from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- EC10
- EC25
- EC50
- EC100
- EC0
- ER0
- ER10
- ER25
- ER50
- ER100
Prioritisation by units:
- Soil dw (g/ha, kg/ha and lbs/acre).
- Soil ww (g/ha, kg/ha and lbs/acre).
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).
Short-term EC50 or LC50 for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of soil microorganisms in the test, generally displayed in milligram per kilo soil (dry weight).
Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. Values are generally displayed in milligram per kilo soil (dry weight).
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 1 study processed
- P/RResults
- NOEC (3.2 months) 4 g/kg soil dw [1]
- EC50 (3.2 months) 8.7 g/kg soil dw [1]
- EC50 (48 days) 8.1 g/kg soil dw [1]
- EC50 (28 days) 12 g/kg soil dw [1]
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 2 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Toxicity to birds
This section summarises the values related to toxicity to birds from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram, per bodyweight per day. Otherwise data is displayed reported as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units .
Prioritisation by dose descriptor type:
- NOEC
- LOEC
- LC50
- LD50
- LOEC
- LOEL
Prioritisation by unit:
- bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day)
- mg/kg bw
- mg/kg diet
- mg/L drinking water.
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for birds provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of birds in the test, generally displayed in milligram per kilo food.
Long-term EC10 or LC10 or NOEC for birds provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the birds in the test, or the no observed effect concentration for birds. Values are generally displayed in milligram per kilo food.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 3 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other | 1 |
Summaries
- 0 summaries submitted
- 0 summaries processed
No data available
Toxicity to mammals
This section summarises the values related to toxicity to mammals (other above-ground organisms) from all registered dossiers for the substance.
More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header.
Study results
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Otherwise data is displayed as provided by the registrant(s).
The availability of additional data beyond the five results displayed is indicated by (…).
Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). Thirdly the display of data is prioritised by units.
Prioritisation by dose descriptor:
- NOEC
- EC50
- LC50
- LD50
- EC100
- LC100
- LD100
- EC0
- LC0
- LD0
- LR50
- LR0
- LR100
- ER50
- ER0
- ER100
Prioritisation by units
- Soil dw (g/ha and mg/cm²)
- Soil ww; (g/ha and mg/cm²)
- µg per animal
- mL/ha; mg/kg bw
- mg/kg diet
- ppm.
- mg/kg dung dw
Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Short-term EC50 or LC50 for mammals provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of mammals in the test, generally displayed in milligram per kilo food.
Long-term EC10 or LC10 or NOEC for mammals provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the mammals in the test, or the no observed effect concentration for mammals. Values are generally displayed in milligram per kilo food.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Toxicological information
This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.
Derived No- or Minimal Effect Level (DN(M)EL)
This section provides information on the derived no- or minimal effect level (DN(M)EL), the level of exposure above which a human should not be exposed to a substance.
When more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.
When more than one result is available per endpoint the ‘worst case’ or most conservative of all the data values provided are displayed, applying a precautionary principal. The aim is to display the lowest values reported as causing the most adverse effects, and hence the broadest possible safety margins for the substance.
Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure.
Registrant can provide information on the long and acute/short term exposure for both systemic and local effects of inhalation exposure of workers and/or general population by selecting one of the following hazard assessment conclusions:
- DNEL (Derived No-Effect Level)
- DMEL (Derived Minimum Effect Level) - not included for short–term effects
- Other toxicological threshold
- High hazard (no threshold derived)
- Medium hazard (no threshold derived)
- Low hazard (no threshold derived)
- Insufficient data available (further information necessary)
- Hazard unknown (no further information necessary)
- No hazard identified
- Hazard unknown but no further hazard information necessary as no exposure expected
Prioritisation of display occurs based on the order above. If a threshold is derived, the type of hazard assessment conclusion is displayed and the registered threshold is reported in (nano/micro/milli)gram per cubic metre. If more than one DNEL/DMEL is available the most conservative (i.e. the lowest numerical data) is displayed.
Information on the most sensitive study can be provided by the registrants as:
- Acute toxicity
- Repeated dose toxicity
- Effect on fertility
- Developmental toxicity/teratogenicity
- Neurotoxicity
- Immunotoxicity
- Sensitisation (skin)
- Sensitisation (respiratory tract)
- Carcinogenicity
- Skin irritation/corrosion
- Irritation (respiratory tract)
- Genetic toxicity
Dermal exposure provides information on the substance’s hazard assessment conclusions regarding dermal exposure (for workers).
See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term:
- ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added
The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day.
Data for workers – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for workers).
Registrant can provide information on eye exposure by selecting one of the following hazard assessment conclusions:
- High hazard (no threshold derived)
- Medium hazard (no threshold derived)
- Low hazard (no threshold derived)
- Hazard unknown (no further information necessary)
- No hazard identified
- Hazard unknown but no further hazard information necessary as no exposure expected
Data for general population – eye exposure provides information on the substance’s hazard assessment conclusions regarding eye exposure (for the general population).
Registrant can provide information on eye exposure as mentioned above for ‘Data for workers – eye exposure.’
M/C Summaries
- 1 summary submitted
- 1 summary processed
The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.
Data for WORKERS
INHALATION Exposure | Threshold | Most sensitive study |
---|---|---|
Systemic Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | (DNEL) 1 mg/m³ | irritation (respiratory tract) |
Acute /short term: | (DNEL) 4 mg/m³ | irritation (respiratory tract) |
DERMAL Exposure | Threshold | Most sensitive study |
Systemic Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | (Low hazard (no threshold derived)) | - |
Acute /short term: | (Low hazard (no threshold derived)) | - |
EYE Exposure | ||
Medium hazard (no threshold derived) |
Data for the GENERAL POPULATION
INHALATION Exposure | Threshold | Most sensitive study |
---|---|---|
Systemic Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | (DNEL) 1 mg/m³ | irritation (respiratory tract) |
Acute /short term: | (DNEL) 4 mg/m³ | irritation (respiratory tract) |
DERMAL Exposure | Threshold | Most sensitive study |
Systemic Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
Local Effects | ||
Long-term: | (Low hazard (no threshold derived)) | - |
Acute /short term: | (Low hazard (no threshold derived)) | - |
ORAL Exposure | Threshold | Most sensitive study |
Systemic Effects | ||
Long-term: | No hazard identified | |
Acute /short term: | No hazard identified | |
EYE Exposure | ||
Medium hazard (no threshold derived) |
Toxicokinetics, metabolism, and distribution
This section displays the values (see below) related to toxicokinetics, metabolism, and distribution from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study result data.
Summary
Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below.
Registrants can register their substance’s bioaccumulation properties as:
- High bioaccumulation potential
- Low bioaccumulation potential
- No bioaccumulation potential
Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. If multiple values are available, the most conservative value (the highest percentage) is displayed.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: basic toxicokinetics
- 7 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: basic toxicokinetics
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 6 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 1 |
Study data: dermal absorption
- 2 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: dermal absorption
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | |
Exposure cons. | |
Other | 1 |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Bioaccumulation potential:
- No bioaccumulation potential
Acute toxicity
This section displays the values related to acute toxicity from all registered dossiers for the substance.
Study results - oral
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per kilo bodyweight. The availability of additional data beyond the five results displayed is indicated by (…).
Results
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by dose descriptor type:
- LD50
- LD50 cut-off
- Discriminating dose
- LD0
- LD100
- LDLo
- Approximate LD50
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Applicant’s summary and conclusion – Interpretation of results (oral). Registrants can choose from the following (picklist) conclusions:
- Category 1 based on GHS criteria
- Category 2 based on GHS criteria
- Category 3 based on GHS criteria
- Category 4 based on GHS criteria
- Category 5 based on GHS criteria
- Study cannot be used for classification
- GHS criteria not met
- Extremely toxic
- Very toxic
- Highly toxic
- Toxic
- Moderately toxic
- Slightly toxic
- Toxicity category I
- Toxicity category II
- Toxicity category III
- Toxicity category IV
- Toxicity category V
- Practically nontoxic
- Harmful
- Relatively harmless
- Not classified
- Other
Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above.
Note: Registrants can also select ‘other’ as the picklist conclusion. If so, the data provided is not processed for the Brief Profile.
Study results - dermal
Results
See information under ‘Study results oral’.
Applicant’s summary and conclusion – Interpretation of results (dermal). See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’.
Study results - Inhalation
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per kilo bodyweight. The availability of additional data beyond the five results displayed is indicated by (…).
Results
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Within each of these categories, data is prioritised further by duration (in hours), with longer prioritised over shorter.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by dose descriptor type:
- LC50
- LC50 cut-off
- Discriminating conc.
- LC0
- LC1
- LC100
- LCLo
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Applicant’s summary and conclusion – Interpretation of results (inhalation). See information under ‘Applicant’s summary and conclusion – interpretation of results (oral)’.
Study results - other routes
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per kilo bodyweight. The availability of additional data beyond the five results displayed is indicated by (…) icon.
Results
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritization by the dose descriptor type:
- EC50
- LC50
- LD50
- EC0
- LC0
- LD0
- EC100
- LC100
- LD100
- LCLo
- LDLo
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary
Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above, i.e. the minimum numerical value associated with the highest priority picklist item.
Oral route provides substance information on the substance’s acute toxicity via the oral route. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed
- No study available
If an adverse effect is observed, data can be provided as LD 50 or discriminating dose, displayed here in milligrams per kilogram bodyweight.
Dermal route provides substance information on the substance’s acute toxicity via the dermal route. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed
- No study available
If an adverse effect is observed, data can be provided as LD 50 or discriminating dose, displayed here in milligrams per kilogram bodyweight.
Inhalation route provides substance information on the substance’s acute toxicity via the inhalation route. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed
- No study available
If an adverse effect is observed, data can be provided as LD 50 or discriminating concentration, displayed here in milligram per cubic metre.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
oral
- 7 studies submitted
- 1 study processed
- P/RResults
- LD50 2 000 mg/kg bw (rat) [1]
- M/CInterpretations of results
- Not classified [1]
Type of Study provided
oral
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 2 | |||
Weight of evidence | ||||
Other | 4 |
Data waiving | |
---|---|
no waivers |
inhalation
- 3 studies submitted
- 1 study processed
- P/RResults
- LC50 (4 h) 6.04 mg/L air (rat) [1]
- M/CInterpretations of results
- Category 5 based on GHS criteria [1]
inhalation
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | 1 | ||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
dermal
- 2 studies submitted
- 1 study processed
- P/RResults
- LD50 2 500 mg/kg bw (rabbit) [1]
- M/CInterpretations of results
- Not classified [1]
dermal
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
other routes
- 0 studies submitted
- 0 studies processed
No data available
other routes
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Oral route:
- No adverse effect observed Discriminating dose 2 000 mg/kg bw
- Inhalation route:
- Adverse effect observed Discriminating conc. 6.04 mg/L air
- Dermal route:
- No adverse effect observed Discriminating dose 2 500 mg/kg bw
Irritation / corrosion
This section displays the values related to irritation and corrosion from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below.
Skin irritation/corrosion provides substance information on the substance’s irritation/corrosion effect on the skin. Registrants can choose from the following picklist endpoint conclusions/effect levels:
Endpoint conclusion – picklist
- Adverse effect observed (irritating)
- Adverse effect observed (corrosive)
- No adverse effect observed (not irritating)
- No study available
Eye irritation provides substance information on the substance’s irritation effect on the eye. Registrants can choose from the following picklist endpoint conclusions/effect levels:
- Adverse effect observed (irreversible damage)
- Adverse effect observed (irritating)
- No adverse effect observed (not irritating)
- No study available
Respiratory irritation provides substance information on the substance’s irritation effect on the respiratory system. Registrants can choose from the following picklist endpoint conclusions/effect levels:
- <
- Adverse effect observed (irritating)
- No adverse effect observed (not irritating)
- No study available
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: skin
- 9 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: skin
Studies with data | ||||
---|---|---|---|---|
Key study | 3 | |||
Supporting study | 2 | |||
Weight of evidence | ||||
Other | 2 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
Study data: eye
- 17 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: eye
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 4 | |||
Weight of evidence | ||||
Other | 10 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Skin
- Adverse effect observed (irritating)
- Eye
- Adverse effect observed (irritating)
- Respiratory
- Adverse effect observed (irritating)
Sensitisation
This section displays the values related to sensitisation from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below.
Skin sensitisation provides substance information on the substance’s sensitisation effect on the skin. Registrants can choose from the following picklist endpoint conclusions:
- Adverse effect observed
- No adverse effect observed (not irritating)
- No study available
Respiratory sensitisation provides substance information on the substance’s sensitisation effect on the respiratory system. Registrants can choose the same picklist endpoint conclusions as mentioned under ‘Skin sensitisation’.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: skin
- 4 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: skin
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | |||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 3 |
Exposure cons. | |
Other |
Study data: respiratory
- 0 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: respiratory
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Skin sensitisation
- No study available
- Respiratory sensitisation
- No study available
Repeated dose toxicity
This section displays the values related to repeated dose toxicity from all registered dossiers for the substance.
Study results oral
Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. Thirdly the display of data is prioritised by units.
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligrams per kilogram bodyweight per day.
The availability of additional data beyond the five results displayed is indicated by (…).
Prioritization by dose descriptor type:
- NOAEL
- LOAEL
- NOEL
- LOEL
- BMD05
- BMDL05
- BMDL10
- BMC05
- BMCL05
- BMCL10
- no NOAEL identified
Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. level’ as the dose descriptor. If so, the data provided is not processed for the Brief Profile.
Prioritisation by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by units:
- mg/kg bw/day (nominal/actual dose received)
- mg/kg diet
- mg/L drinking water
- mg/kg bw (total dose)
- ppm
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Study results inhalation
Processable data for study results is prioritised by dose descriptor type (see list below) and subsequently further prioritised by the test species. Thirdly the display of data is prioritised by units.
Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per litre air.
The availability of additional data beyond the five results displayed is indicated by (…).
Prioritization by dose descriptor type:
- NOAEL
- LOAEL
- NOEL
- LOEL
- NOAEC
- NOEC
- LOAEC
- LOEC
- BMD05
- BMDL05
- BMDL10
- BMC05
- BMCL05
- BMCL10
- no NOAEL identified
- no NOAEC identified
Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. level’ as the dose descriptor. If so, the data provided is not processed for the Brief Profile.
Prioritization by test species:
- See ‘Study results oral: Prioritization by test species’
Prioritisation by unit:
- mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical))
- ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received)
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Study results dermal
See ‘Study results Oral’, except:
Prioritisation by unit:
- mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day)
- mg/kg bw (total dose)
- mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical))
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary oral – systemic effects
Processable data for the summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary dermal - systemic effects
See ‘Summary oral systemic effects’
Summary dermal - local effects
See ‘Summary oral systemic effects’, except:
Unit of measure: mg/cm2
Summary inhalation - systemic effects
See ‘Summary oral Route’, except:
Unit of measure: mg/m3
Prioritisation by dose descriptor type:
- NOAEC
- LOAEC
- BMCL05
- BMC05
- BMCL10
- T25
Summary inhalation - local effects
‘See Summary inhalation systemic effects’
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: oral
- 12 studies submitted
- 0 studies processed
No automatically processable data submitted
Type of Study provided
Study data: oral
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 5 | 3 | ||
Weight of evidence | ||||
Other | 2 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
Study data: inhalation
- 6 studies submitted
- 0 studies processed
No automatically processable data submitted
Study data: inhalation
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 2 | |||
Weight of evidence | ||||
Other | 2 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
Study data: dermal
- 2 studies submitted
- 0 studies processed
No automatically processable data submitted
Study data: dermal
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 2 |
Exposure cons. | |
Other |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Inhalation route - systemic effects:
- No adverse effect observed NOAEC 107 mg/m³ (subacute, rat)
- Inhalation route - local effects:
- No adverse effect observed NOAEC 107 mg/m³ (subacute, rat)
Genetic toxicity
This section displays the values related to genetic toxicity from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary
Processable data for study results is prioritised by endpoint conclusion: the most conservative value is displayed.
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: in vitro
- 14 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: in vitro
Studies with data | ||||
---|---|---|---|---|
Key study | 6 | |||
Supporting study | 4 | |||
Weight of evidence | ||||
Other | 4 |
Data waiving | |
---|---|
no waivers |
Study data: in vivo
- 0 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: in vivo
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Summaries
- 1 summary submitted
- 0 summaries processed
No automatically processable data submitted
Carcinogenicity
This section displays the values related to carcinogenicity from all registered dossiers for the substance.
Study results
Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm.
Summary oral route
Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Note: Registrants can also select ‘other’ as the test species. If so, the data provided is not processed for the Brief Profile.
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary dermal route
See ‘Summary oral Route’
Summary inhalation route
See ‘Summary oral Route’, except:
Measurement units: mg/m3
Prioritisation by dose descriptor type:
- NOAEC
- LOAEC
- BMCL05
- BMC05
- BMCL10
- T25
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
- 14 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Studies with data | ||||
---|---|---|---|---|
Key study | 1 | |||
Supporting study | ||||
Weight of evidence | ||||
Other | 12 |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Oral route:
- No adverse effect observed NOAEL 517 mg/kg bw/day (chronic, rat)
Toxicity to reproduction
This section displays the values related to reproductive toxicity from all registered dossiers for the substance.
Study results
Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm.
Summary effect on fertility oral route
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Note: Registrants can also select ‘other’ as the test species. If so, the data provided is not processed for the Brief Profile.
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary effect on fertility dermal route
See ‘Summary effect on fertility oral route’
Summary effect on fertility inhalation route
See ‘Summary effect on fertility oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Summary developmental toxicity oral route
See ‘Summary effect on fertility oral route’
Summary developmental toxicity dermal route
See ‘Summary effect on fertility oral route’
Summary developmental toxicity inhalation route
See ‘Summary effect on fertility oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Study results
Study data: reproduction
- 3 studies submitted
- 0 studies processed
Study data not processed for brief profile
Type of Study provided
Study data: reproduction
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | 1 | 1 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
Not feasible | |
Sci. unjustified | 1 |
Exposure cons. | |
Other |
Study data: developmental
- 7 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: developmental
Studies with data | ||||
---|---|---|---|---|
Key study | 2 | |||
Supporting study | 1 | 4 | ||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
Study data: other studies
- 0 studies submitted
- 0 studies processed
Study data not processed for brief profile
Study data: other studies
Studies with data | ||||
---|---|---|---|---|
Key study | ||||
Supporting study | ||||
Weight of evidence | ||||
Other |
Data waiving | |
---|---|
no waivers |
M/C Summaries
- 1 summary submitted
- 1 summary processed
- Effect on developmental toxicity
- Oral route:
- No adverse effect observed NOAEL 582 mg/kg bw/day (subacute, mouse)
Neurotoxicity
This section displays the values related to neurotoxicity from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary oral route
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data is generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Summary dermal route
See ‘Summary oral route’
Summary inhalation route
See ‘Summary oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Immunotoxicity
This section displays the values related to immunotoxicity from all registered dossiers for the substance.
Study results
For this endpoint registrants do not provide study results that are processable for the Brief Profile.
Summary oral route
Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Displayed is the most conservative of the prioritised value(s). If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion.
Data generally displayed in milligrams per kilogram bodyweight per day.
Prioritization by test species:
- Rat
- Mouse
- Dog
- Cat
- Cattle
- Gerbil
- Guinea pig
- Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian)
- Hen
- Miniature swine
- Monkey
- Pig
- Primate
- Rabbit
- Sheep
Prioritisation by descriptor type:
- NOAEL
- LOAEL
- T25
- BMDL05
- BMD05
- BMDL10
Prioritisation by test type:
- Chronic
- Subchronic
- Subacute
Prioritisation by endpoint conclusion:
- Adverse effect observed
- No adverse effect observed
- No study available / no study available (further information necessary)
Note: Registrants can also select ‘other’ as the test species, dose descriptor type and/or the unit of measure. If so, the data provided is not processed for the Brief Profile.
Summary dermal route
See ‘Summary oral route’
Summary inhalation route
See ‘Summary oral route’, except:
Dose descriptor prioritization:
- NOAEC
- LOAEC
- BMCL01
- BMC05
- BMCL10
Measurement units: mg/m3
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
Endocrine disrupter mammalian screening - in vivo
This section displays the values related to endocrine disrupter mammalian screening from all registered dossiers for the substance.
Study results
If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. The % is based on count of values provided.
Type of study provided
This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications.
Data not provided by the registrant
- Physical and chemical properties
- Appearance/physical state / colour
- Melting/freezing point
- Boiling point
- Density
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising
- Oxidation reduction potential
- pH
- Dissociation constant
- Viscosity
- Environmental fate and pathways
- Phototransformation in air
- Hydrolysis
- Phototransformation in water
- Phototransformation in soil
- Biodegradation in water - screening tests
- Biodegradation in water & sediment - simulation tests
- Biodegradation in soil
- Bioaccumulation: aquatic / sediment
- Bioaccumulation: terrestrial
- Adsorption/desorption
- Henrys law constant (H)
- Distribution modelling
- Ecotoxicological information
- Predicted No-Effect Concentration (PNEC)
- Short–term toxicity to fish
- Long–term toxicity to fish
- Short–term toxicity to aquatic invertebrates
- Long–term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Sediment toxicity
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to terrestrial macroorganisms except arthropods
- Toxicity to terrestrial arthropods
- Toxicity to terrestrial plants
- Toxicity to soil microorganisms
- Toxicity to birds
- Toxicity to mammals
- Toxicological information
- Derived No- or Minimal Effect Level (DN(M)EL)
- Toxicokinetics, metabolism, and distribution
- Acute toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Neurotoxicity
- Immunotoxicity
- Endocrine disrupter mammalian screening - in vivo
The brief profile is based on non-confidential data contained in ECHA’s databases at the time of generation. Please be aware that as additional data is submitted to ECHA, the brief profile will also be updated to reflect the new situation. All data remain the property of its respective owners.
Note that the brief profile is an automatically generated summary and that not all available data may be displayed. The content is subject to change without prior notice. The information has not been reviewed or verified by ECHA or any other authority. The Agency thus cannot guarantee the correctness of the information displayed. The identification of applicable legislative frameworks is done automatically and without manual verification. Therefore this does not constitute official and legally binding information. To confirm if a substance is covered by a specific legislative framework the official publication should be consulted.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner. The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. This brief profile is covered by the ECHA Legal Notice.
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